Aptamer superstructure-based electrochemical biosensor for sensitive detection of ATP in rat brain with in vivo microdialysis

The Analyst ◽  
2019 ◽  
Vol 144 (5) ◽  
pp. 1711-1717 ◽  
Author(s):  
Yanan Jiang ◽  
Wenjie Ma ◽  
Wenliang Ji ◽  
Huan Wei ◽  
Lanqun Mao

An electrochemical biosensor with an aptamer superstructure as the recognition element is demonstrated for highly sensitive detection of ATP in the cerebral system.

2021 ◽  
Vol 57 (75) ◽  
pp. 9554-9557
Author(s):  
Fanpeng Kong ◽  
Ying Li ◽  
Xiao Li ◽  
Xiaoxiu Wang ◽  
Guanyu Fu ◽  
...  

Screening results indicated that DCO-5 exhibited the highest sensitivity to viscosity and was insensitive to polarity or pH, and enables the successful detection of viscosity changes in vivo.


RSC Advances ◽  
2018 ◽  
Vol 8 (57) ◽  
pp. 32454-32460 ◽  
Author(s):  
Hongying Wang ◽  
Zhe Chi ◽  
Ying Cong ◽  
Zhuangzhuang Wang ◽  
Fei Jiang ◽  
...  

The fluorescence assay for detecting Pseudomonas aeruginosa was achieved by the aptamer-CDs/GD system which exhibited obvious fluorescence recovery when encountered the cells of P. aeruginosa.


2017 ◽  
Vol 9 (13) ◽  
pp. 2082-2088 ◽  
Author(s):  
Dan Cheng ◽  
Xi Li ◽  
Yan Qiu ◽  
Qi Chen ◽  
Jian Zhou ◽  
...  

A modified matrix of an iron terephthalate metal–organic framework (MIL-53(Fe)), as a simple and efficient electroactive material for use as an electrochemical biosensor, was investigated.


The Analyst ◽  
2020 ◽  
Vol 145 (12) ◽  
pp. 4204-4211 ◽  
Author(s):  
Wenrui Ma ◽  
Lulu Liu ◽  
Yi Xu ◽  
Li Wang ◽  
Li Chen ◽  
...  

A microfluidic biosensor was designed for rapid and highly sensitive detection of endotoxin, which could be detected within 0.5 h and with a detection limit of 0.5 ng mL−1.


2015 ◽  
Vol 51 (57) ◽  
pp. 11467-11469 ◽  
Author(s):  
Koichi Abe ◽  
Yoshiyuki Murakami ◽  
Atsuro Tatsumi ◽  
Koichi Sumida ◽  
Aki Kezuka ◽  
...  

Aptamers are labeled by luciferase via a zinc finger (ZF) by introduction into a ZF recognition sequence to the aptamer. It enables us to construct a highly sensitive detection system.


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