Magneto-controlled flow-injection device for electrochemical immunoassay of alpha-fetoprotein on magnetic beads using redox-active ferrocene derivative polymer nanospheres

The Analyst ◽  
2019 ◽  
Vol 144 (4) ◽  
pp. 1433-1441 ◽  
Author(s):  
Bin Li ◽  
Wenyuan Pu ◽  
Houxi Xu ◽  
Lilin Ge ◽  
Hang Fai Kwok ◽  
...  
Keyword(s):  
Magnetic Beads ◽  
Alpha Fetoprotein ◽  
Electrochemical Immunoassay ◽  
Injection Device ◽  
Ferrocene Derivative ◽  
Redox Active ◽  
Flow Through ◽  
Polymer Nanospheres ◽  
Controlled Flow ◽  
Electrochemical Immunosensing

A new electrochemical immunosensing protocol by coupling with a magneto-controlled flow-through microfluidic device was developed for the sensitive detection of alpha-fetoprotein (AFP) on magnetic beads (MB) using ferrocene derivative polymer nanospheres (FDNP) as the electroactive mediators.

Prussian blue-doped PAMAM dendrimer nanospheres for electrochemical immunoassay of human plasma cardiac troponin I without enzymatic amplification

2021 ◽  
Author(s):  
Fangfang Ma ◽  
Gaoshun Ge ◽  
Yizhen Fang ◽  
Erru Ni ◽  
Yuanyuan Su ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Cardiac Troponin ◽  
Troponin I ◽  
Biological Fluids ◽  
Pamam Dendrimer ◽  
Cardiac Troponin I ◽  
Electrochemical Immunoassay ◽  
Accurate Identification ◽  
Enzymatic Amplification ◽  
Electrochemical Immunosensing

Rapid and accurate identification of cardiac troponin I (cTnl) in biological fluids is very essential for judging acute myocardial infarction (AMI). Herein, we constructed an enzyme-free electrochemical immunosensing system for...

Novel Electrochemical Immunoassay for Carcinoembryonic Antigen Using Ferrocenyl Polymer Nanospheres

2016 ◽  
Vol 49 (18) ◽  
pp. 2931-2942 ◽  
Author(s):  
Yanling Zhao ◽  
Ruiping Zhang ◽  
Hui Zhang ◽  
Xianmei Xie
Keyword(s):  
Carcinoembryonic Antigen ◽  
Electrochemical Immunoassay ◽  
Polymer Nanospheres

Enzyme-catalyzed silver deposition on irregular-shaped gold nanoparticles for electrochemical immunoassay of alpha-fetoprotein

2012 ◽  
Vol 755 ◽  
pp. 62-68 ◽  
Author(s):  
Wenqiang Lai ◽  
Dianping Tang ◽  
Xiaohua Que ◽  
Junyang Zhuang ◽  
Libing Fu ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Alpha Fetoprotein ◽  
Electrochemical Immunoassay ◽  
Silver Deposition

A simple portable low-pressure healant-injection device for repairing damaged composite laminates

2017 ◽  
Vol 45 (4) ◽  
pp. 360-375 ◽  
Author(s):  
WL Lai ◽  
AYH Cheah ◽  
RCO Ruiz ◽  
NGW Lo ◽  
KQJ Kuah ◽  
...  
Keyword(s):  
Carbon Fibre ◽  
Composite Laminates ◽  
Low Pressure ◽  
Reinforced Composites ◽  
Injection Device ◽  
Destructive Testing ◽  
Micro Cracks ◽  
Flow Through ◽  
Injection Unit ◽  
Fibre Reinforced Composites

This article presents the outcomes of an undergraduate design-for-industry team-driven project to develop a portable low-pressure healant-injection device. The developed healant-injection device is intended to use for teaching purpose. The students practice some of the techniques of repairing damaged composite laminates, as part of an engineering composite-related course, which mainly covers the fundamentals and applications of composite laminates. The healant-injection device works by introducing resin into damaged site that can assist the healant to flow through the network of micro-cracks in a low-pressure environment. The device comprises three components: a chamber featuring a (rectangular box) cover made from acrylic that is intended to cover a damaged surface in a low-pressure environment, an injection unit and a vacuum pump unit. Only the vacuum chamber was designed from scratch by the team; the other components were sourced commercially. The repair of composite laminates can be performed using a low viscosity resin, which is made to flow through a hole on the roof of the chamber, assisted by the injection unit (fluid dispenser), from which the resin flows into the damaged (micro-cracks) site; the very low pressure environment (25–29 inHg) in the chamber facilitates the removal of air pockets in the cracks. The composite laminates featured in this project are carbon fibre reinforced composite laminates, which are of great interest to the aerospace industry. Testing and evaluation were carried out by the team to assess the performance of the healant-injection device using impacted carbon fibre reinforced composites. To assist the team to study the effectiveness of the repair, (a) an ultrasonic C-scan equipment for non-destructive testing was used to assess the extent of the healant flow into the crack regions within the damaged carbon fibre reinforced composites and (b) a compression after impact test was carried out to assess the recovery of the compressive strength of the repaired carbon fibre reinforced composites compare to the pristine and damaged samples in different number of carbon-fibre plies (10, 16, 24 and 32).

Highly sensitive electrochemical immunoassay for human IgG using double-encoded magnetic redox-active nanoparticles

2010 ◽  
Vol 171 (3-4) ◽  
pp. 457-464 ◽  
Author(s):  
Dianping Tang ◽  
Juan Tang ◽  
Biling Su ◽  
Huafeng Chen ◽  
Jianxin Huang ◽  
...  
Keyword(s):  
Electrochemical Immunoassay ◽  
Human Igg ◽  
Redox Active ◽  
Highly Sensitive ◽  
Active Nanoparticles

Novel gold-decorated polyaniline derivatives as redox-active species for simultaneous detection of three biomarkers of lung cancer

2015 ◽  
Vol 3 (14) ◽  
pp. 2867-2872 ◽  
Author(s):  
Liyuan Wang ◽  
Na Liu ◽  
Zhanfang Ma
Keyword(s):  
Lung Cancer ◽  
Simultaneous Detection ◽  
Active Species ◽  
Tumor Biomarkers ◽  
Electrochemical Immunoassay ◽  
Redox Active

Novel redox-active species including gold-poly(o-aminophenol) and gold-poly(p-phenylenediamine) were synthesized and applied for the electrochemical immunoassay of three tumor biomarkers.

Sign in / Sign up

Export Citation Format

Share Document