scholarly journals Direct sampling mass spectrometry for clinical analysis

The Analyst ◽  
2019 ◽  
Vol 144 (4) ◽  
pp. 1034-1051 ◽  
Author(s):  
Fan Pu ◽  
Spencer Chiang ◽  
Wenpeng Zhang ◽  
Zheng Ouyang

Direct sampling mass spectrometry enables high-performance clinical analysis, such as imaging, drug monitoring and point-of-care testing.

Biosensors ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 32 ◽  
Author(s):  
Beatriz Pérez-Fernández ◽  
Agustín Costa-García ◽  
Alfredo de la Escosura- Muñiz

Pesticides are among the most important contaminants in food, leading to important global health problems. While conventional techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS) have traditionally been utilized for the detection of such food contaminants, they are relatively expensive, time-consuming and labor intensive, limiting their use for point-of-care (POC) applications. Electrochemical (bio)sensors are emerging devices meeting such expectations, since they represent reliable, simple, cheap, portable, selective and easy to use analytical tools that can be used outside the laboratories by non-specialized personnel. Screen-printed electrodes (SPEs) stand out from the variety of transducers used in electrochemical (bio)sensing because of their small size, high integration, low cost and ability to measure in few microliters of sample. In this context, in this review article, we summarize and discuss about the use of SPEs as analytical tools in the development of (bio)sensors for pesticides of interest for food control. Finally, aspects related to the analytical performance of the developed (bio)sensors together with prospects for future improvements are discussed.


The Analyst ◽  
2012 ◽  
Vol 137 (10) ◽  
pp. 2344 ◽  
Author(s):  
Ryan D. Espy ◽  
Nicholas E. Manicke ◽  
Zheng Ouyang ◽  
R. Graham Cooks

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