Electrochemical detection of Alzheimer's disease related substances in biofluids by silica nanochannel membrane modified glassy carbon electrodes

The Analyst ◽  
2018 ◽  
Vol 143 (19) ◽  
pp. 4756-4763 ◽  
Author(s):  
Lin Zhou ◽  
Hao Ding ◽  
Fei Yan ◽  
Weiliang Guo ◽  
Bin Su
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Old Age ◽  
Electrochemical Detection ◽  
Glassy Carbon ◽  
Memory Loss ◽  
Carbon Electrodes ◽  
Glassy Carbon Electrodes ◽  
Brain Functions ◽  
Related Substances

Alzheimer's disease (AD) affects middle- and old-age populations, and causes loss of brain weight, degradation of brain functions and memory loss.

scholarly journals Large interlayer spacing Nb4C3Tx (MXene) promotes the ultrasensitive electrochemical detection of Pb2+ on glassy carbon electrodes

RSC Advances ◽  
2020 ◽  
Vol 10 (41) ◽  
pp. 24697-24704 ◽  
Author(s):  
P. Abdul Rasheed ◽  
Ravi P. Pandey ◽  
Tricia Gomez ◽  
Michael Naguib ◽  
Khaled A. Mahmoud
Keyword(s):  
Electrochemical Detection ◽  
Glassy Carbon ◽  
Interlayer Spacing ◽  
Carbon Electrodes ◽  
Glassy Carbon Electrodes

Large interlayer spacing Nb4C3Tx (MXene) promotes the ultrasensitive electrochemical detection of Pb2+ on glassy carbon electrodes

Selective dopamine detection using aptamer-functionalized glassy carbon electrodes

2015 ◽  
Vol 93 (5) ◽  
pp. 572-577 ◽  
Author(s):  
Ryan Walsh ◽  
Uyen Ho ◽  
Xiao Li Wang ◽  
Maria C. DeRosa
Keyword(s):  
Ascorbic Acid ◽  
Electrochemical Detection ◽  
Glassy Carbon ◽  
Dna Aptamer ◽  
Carbon Electrodes ◽  
Glassy Carbon Electrodes ◽  
Organic Monolayer ◽  
Dopamine Detection ◽  
Redox Active ◽  
Viable Approach

The electrochemical detection of dopamine using glassy carbon electrodes suffers from a lack of selectivity toward the neurotransmitter, as interferences such as other catechol-containing neurochemicals and ascorbic acid can be oxidized at overlapping potentials. Several approaches have been employed to improve the selectivity of these electrodes towards dopamine including electrochemical pretreatment and organic monolayer depositions. Here, we characterize glassy carbon electrodes that were initially passivated through a trifluoromethylphenyl and nitrophenyl monolayer deposition and then functionalized with a specific DNA dopamine aptamer. Passivation with the mixed monolayer cuts off all signals from the redox-active neurochemicals. After functionalization with the DNA aptamer, the dopamine signal is restored and the electrodes are more responsive to dopamine than to any other related catechol-containing compounds or other common neurochemicals such as ascorbic acid. Our findings indicate that aptamer functionalization of glassy carbon electrodes may provide a viable approach for tuning the selectivity of electrochemical detection.

Electrochemical Detection of Lead Ions with Ordered Mesoporous Silica–Modified Glassy Carbon Electrodes

2020 ◽  
Vol 231 (5) ◽  
Author(s):  
Nicoleta Cotolan ◽  
Liana Maria Mureşan ◽  
Andrea Salis ◽  
Lucian Barbu-Tudoran ◽  
Graziella Liana Turdean
Keyword(s):  
Mesoporous Silica ◽  
Electrochemical Detection ◽  
Glassy Carbon ◽  
Lead Ions ◽  
Carbon Electrodes ◽  
Ordered Mesoporous Silica ◽  
Glassy Carbon Electrodes ◽  
Ordered Mesoporous
Sign in / Sign up

Export Citation Format

Share Document