A rainbow ratiometric fluorescent sensor array on bacterial nanocellulose for visual discrimination of biothiols

The Analyst ◽  
2018 ◽  
Vol 143 (14) ◽  
pp. 3415-3424 ◽  
Author(s):  
Samira Abbasi-Moayed ◽  
Hamed Golmohammadi ◽  
Arafeh Bigdeli ◽  
M. Reza Hormozi-Nezhad
Keyword(s):  
Early Diagnosis ◽  
Visual Discrimination ◽  
Crucial Role ◽  
Sensor Array ◽  
Fluorescent Sensor ◽  
Biological Processes ◽  
Bacterial Nanocellulose

The crucial role of biothiols in many biological processes, which turns them into important biomarkers for the early diagnosis of various diseases, the development of an affordable, sensitive and portable probe for the detection and discrimination of these compounds is of great importance.

A nanopaper-based artificial tongue: a ratiometric fluorescent sensor array on bacterial nanocellulose for chemical discrimination applications

Nanoscale ◽  
2018 ◽  
Vol 10 (5) ◽  
pp. 2492-2502 ◽  
Author(s):  
Samira Abbasi-Moayed ◽  
Hamed Golmohammadi ◽  
M. Reza Hormozi-Nezhad
Keyword(s):  
Sensor Array ◽  
Visual Analysis ◽  
Fluorescent Sensor ◽  
Photoluminescence Properties ◽  
Bacterial Nanocellulose ◽  
Carbon Dot ◽  
Chemical Discrimination

We have used the interesting photoluminescence properties of carbon dot-RhodamineB (CD-RhB) nanohybrids to develop a simple and efficient nanopaper-based ratiometric fluorescent sensor array (NRFSA) for visual analysis.

Screening in Ovarian Neoplasm

2019 ◽  
Vol 70 (10) ◽  
pp. 3687-3688
Author(s):  
Alexandra Ligia Dinca ◽  
Valeriu Gabi Dinca ◽  
Silviu Marian Constantinoiu ◽  
Rodica Daniela Birla
Keyword(s):  
Mortality Rate ◽  
Early Diagnosis ◽  
Clinical Examination ◽  
High Mortality ◽  
Crucial Role ◽  
Screening Test ◽  
Ovarian Neoplasm ◽  
Screening Tests

Ovarian neoplasm is extremely aggressive and has a high mortality rate among affected women; therefore, the crucial role of screening tests is easy to understand. Prevention and early diagnosis should be essential priorities in the management of this malignancy. Since a complete and correct clinical examination can select the cases that require specialized investigations, we can consider it a first screening test.

Screening in Ovarian Neoplasm

2019 ◽  
Vol 70 (10) ◽  
pp. 3687-3688
Keyword(s):  
Mortality Rate ◽  
Early Diagnosis ◽  
Clinical Examination ◽  
High Mortality ◽  
Crucial Role ◽  
Screening Test ◽  
Ovarian Neoplasm ◽  
Screening Tests

Ovarian neoplasm is extremely aggressive and has a high mortality rate among affected women; therefore, the crucial role of screening tests is easy to understand. Prevention and early diagnosis should be essential priorities in the management of this malignancy. Since a complete and correct clinical examination can select the cases that require specialized investigations, we can consider it a first screening test. Keywords: ovarian neoplasm, the role of screening; prevention and early diagnosis, screening test

Cerebrospinal Fluid and Blood CX3CL1 as a Potential Biomarker in Early Diagnosis and Prognosis of Dementia

2020 ◽  
Vol 17 (8) ◽  
pp. 709-721
Author(s):  
Agnieszka Kulczyńska-Przybik ◽  
Agnieszka Słowik ◽  
Piotr Mroczko ◽  
Bartłomiej Borawski ◽  
Magdalena Groblewska ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Cognitive Impairment ◽  
Early Diagnosis ◽  
Crucial Role ◽  
Causative Factor ◽  
Older Individuals ◽  
Blood Concentrations ◽  
Diagnosis And Prognosis ◽  
Potential Biomarker

Background: A growing body of evidence highlights the crucial role of neuroinflammation and chemokine involvement in cognitive impairment pathophysiology. Fractalkine (CX3CL1) appears to be a relevant causative factor in the development of dementia, particularly at the early stages of the disease. However, limited data are available on the levels of CX3CL1 in the cerebrospinal fluid (CSF) and blood. Additionally, to date, its utility as a biomarker for MCI or AD has not been studied. Objective: The aim of the present study was to evaluate the clinical utility of CX3CL1 in the early diagnosis of cognitive impairment. We also compared the diagnostic usefulness of CX3CL1 with other biomarkers associated with neuroinflammation. Methods: A total of 60 patients with cognitive impairment, including 42 patients with AD and 18 subjects with MCI, as well as 20 cognitively healthy controls were enrolled in the study. CSF and blood concentrations of CX3CL1, CCL-2, and YKL-40 were measured by ELISA. Results: Significantly higher CSF and blood concentrations of CX3CL1 were observed in MCI and AD patients compared to older individuals without cognitive impairment. The increase in the levels of CX3CL1 and YKL-40 in non-demented subjects was associated with MCI. The area under the ROC curve for CX3CL1 in MCI subjects was larger in comparison to classical AD markers. Conclusion: Presented results indicate a crucial role of CX3CL1 in the pathology of cognitive impairment and the potential usefulness of this protein in the early diagnosis of MCI and AD.

Label-free non-invasive fluorescent pattern discrimination of thiols and chiral recognition of cysteine enantiomers in biofluids using a bioinspired copolymer–Cu2+ hybrid sensor array regulated by pH

2018 ◽  
Vol 6 (42) ◽  
pp. 6877-6883 ◽  
Author(s):  
Zi-Yang Lin ◽  
Xin-Yue Han ◽  
Zi-Han Chen ◽  
Guoyue Shi ◽  
Min Zhang
Keyword(s):  
Crucial Role ◽  
Chiral Recognition ◽  
Sensor Array ◽  
Pattern Discrimination ◽  
Biological Processes ◽  
Label Free ◽  
Non Invasive ◽  
Fluorescent Pattern ◽  
Difficult Issue

Thiols play a crucial role in various biological processes, and the discrimination of thiols in biofluids is a significant but difficult issue.

Epitaxial YBa2Cu3O7-8 films : Crucial role of growth-induced linear defects in microwave properties

2001 ◽  
Vol 11 (PR11) ◽  
pp. Pr11-47-Pr11-52
Author(s):  
V. M. Pan ◽  
V. S. Flis ◽  
V. A. Komashko ◽  
O. G. Plys ◽  
C. G. Tretiatchenko ◽  
...  
Keyword(s):  
Crucial Role ◽  
Microwave Properties ◽  
Linear Defects

ON THE ROLE OF ENDOSCOPIC RESEARCH IN EARLY DIAGNOSIS OF ENT PATHOLOGY AND VOICE DISORDERS

2019 ◽  
Vol 98 (5) ◽  
pp. 175-178
Author(s):  
E.Yu. Radtsig ◽  
◽  
E.N. Kotova ◽  
M.R. Bogomilskiy ◽  
I.E. Bulynko ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Voice Disorders
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