Highly labeled methylene blue-ds DNA silica nanoparticles for signal enhancement of immunoassays: application to the sensitive detection of bacteria in human platelet concentrates

The Analyst ◽  
2018 ◽  
Vol 143 (10) ◽  
pp. 2293-2303 ◽  
Author(s):  
Romaric Bonnet ◽  
Carole Farre ◽  
Lionel Valera ◽  
Ludivine Vossier ◽  
Fanny Léon ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Silica Nanoparticles ◽  
Human Platelet ◽  
Signal Enhancement ◽  
Sensitive Detection ◽  
Bacteria Detection ◽  
Electrochemical Immunoassay ◽  
Platelet Concentrates

A nanoparticle-based electrochemical immunoassay for bacteria detection in platelet concentrates.

Sensitive electrochemical immunoassay with signal enhancement based on nanogold-encapsulated poly(amidoamine) dendrimer-stimulated hydrogen evolution reaction

The Analyst ◽  
2015 ◽  
Vol 140 (23) ◽  
pp. 7948-7954 ◽  
Author(s):  
Ai-Li Sun
Keyword(s):  
Hydrogen Evolution ◽  
Hydrogen Evolution Reaction ◽  
Carbohydrate Antigen ◽  
Electrochemical Immunosensor ◽  
Signal Enhancement ◽  
Sensitive Detection ◽  
Electrochemical Immunoassay ◽  
Related Protein

A new electrochemical immunosensor with signal enhancement was designed for sensitive detection of disease-related protein (human carbohydrate antigen 19-9, CA 19-9 used in this case).

Adsorption of anti-Cra by human platelet concentrates

Transfusion ◽  
1991 ◽  
Vol 31 (3) ◽  
pp. 286-286 ◽  
Author(s):  
WJ Judd ◽  
EA Steiner ◽  
V Miske
Keyword(s):  
Human Platelet ◽  
Platelet Concentrates

A photoelectrochemical biosensor based on methylene blue sensitized Bi5O7I for sensitive detection of PSA

2021 ◽  
Author(s):  
Xuelian Xiang ◽  
Yanlin Wang ◽  
Yanhui Zhang ◽  
Ruo Yuan ◽  
Shangping Wei
Keyword(s):  
Methylene Blue ◽  
Sensitive Detection ◽  
Photoelectrochemical Biosensor ◽  
Signal Probe

Herein, bismuth oxyiodide (Bi5O7I) was used as a signal probe to construct an effective sensitization structure with methylene blue (MB), combined with protein conversion strategy, and a photoelectrochemical (PEC) biosensor was constructed...

scholarly journals Treatment of T. cruzi infected human platelet concentrates with aminomethyltrimethyl psoralen (AMT) and ultravioleta (UV-A) light: preliminary results

1996 ◽  
Vol 29 (1) ◽  
pp. 47-49 ◽  
Author(s):  
Hélio Moraes-Souza ◽  
José Orlando Bordin ◽  
Leslie Bardossy ◽  
Morris A. Blajchman
Keyword(s):  
Ascorbic Acid ◽  
Chagas Disease ◽  
Untreated Control ◽  
Blood Donors ◽  
Human Platelet ◽  
Gentian Violet ◽  
Platelet Concentrates ◽  
Preliminary Results ◽  
Combined Use

The present measures adopted to prevent transfusion-associated Chagas' disease include screening of blood donors. and/or the inactivation of T. cruzi in collected blood using gentian violet (GV) as a trypanocidal agent. In this study, we investigated the efficacy of the combined use of AMT and UV-A in inactirating T. cruzi in infected human platelet cuncentrates. Human platelet concentrates were infected with T. cruzi (2x10/ml) of the Y strain transfered to PL 269 (Fenwal Laboratories) containers and treated with GV (250řg,/ml). and ascorbic acid (1 mg/ml); GV. ascorbic acid and UV-A; GV and UV-A; AMT (40/tG/ml) and ascorbic acid; AMT, ascorbic acid and UV-A; AMT and UV-A; UV-A alone; and untreated (control). All UV-A treated platelet concentrates were exposed to UV-A doses of 24, 92, 184, 276, 368 and 644 kj/m². and the microscopical research of active T. cruzi was performed, using the microhematocrit technique, 1, 6 and 24 hours after each treatment. A high number of active forms of T. cruzi was observed in all condictions, except when GV was used as the trypanocidal agent, providing evidence of the failure of AMT and UV-A in inactivating T cruzi in infected human platelet concentrates.

A rabbit model for monitoring in vivo viability of human platelet concentrates using flow cytometry

Transfusion ◽  
2002 ◽  
Vol 42 (6) ◽  
pp. 711-718 ◽  
Author(s):  
Valery Leytin ◽  
David J. Allen ◽  
Meera Mody ◽  
Margaret L. Rand ◽  
Barbara Hannach ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Human Platelet ◽  
Rabbit Model ◽  
Platelet Concentrates
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