scholarly journals Evaluation of the toxic potential of arecoline toward the third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ) Bg9

2018 ◽  
Vol 7 (3) ◽  
pp. 432-443 ◽  
Author(s):  
Barkha Shakya ◽  
Yasir Hasan Siddique
Keyword(s):  
Drosophila Melanogaster ◽  
Areca Nut ◽  
Carcinogenic Agent ◽  
The Third ◽  
Toxic Potential ◽  
Transgenic Drosophila ◽  
Third Instar Larvae

Arecoline is the key component of areca nut and has been suggested as a carcinogenic agent.

scholarly journals Evaluation of the Toxic Potential of Graphene Copper Nanocomposite (GCNC) in the Third Instar Larvae of Transgenic Drosophila melanogaster (hsp70-lacZ)Bg9

PLoS ONE ◽  
2013 ◽  
Vol 8 (12) ◽  
pp. e80944 ◽  
Author(s):  
Yasir Hasan Siddique ◽  
Ambreen Fatima ◽  
Smita Jyoti ◽  
Falaq Naz ◽  
Rahul ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
The Third ◽  
Toxic Potential ◽  
Transgenic Drosophila ◽  
Third Instar Larvae

Evaluation of the toxic potential of calcium carbide in the third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ)Bg9

Chemosphere ◽  
2015 ◽  
Vol 139 ◽  
pp. 469-478 ◽  
Author(s):  
Mohd. Danish ◽  
Ambreen Fatima ◽  
Saba Khanam ◽  
Smita Jyoti ◽  
Rahul ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Calcium Carbide ◽  
The Third ◽  
Toxic Potential ◽  
Transgenic Drosophila ◽  
Third Instar Larvae

scholarly journals Protective role of curcumin against the toxic effects of cyclophosphamide in the third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ)Bg9

2012 ◽  
Vol 2 (1) ◽  
pp. 2 ◽  
Author(s):  
Yasir Hasan Siddique
Keyword(s):  
Drosophila Melanogaster ◽  
Tissue Damage ◽  
Protective Role ◽  
Toxic Effects ◽  
Hsp70 Expression ◽  
The Third ◽  
Dose Dependent ◽  
Transgenic Drosophila ◽  
Third Instar Larvae

In the present study the effects of curcumin was studied against the toxic effects induced by 0.025 and 0.050 ml/ml of cyclophosphamide (CP) in the third instar larvae of transgenic <em>Drosophila melanogaster (hsp70-lacZ)Bg9</em> using hsp70 expression and dye exclusion test as a parameter. The exposure of the third instar larvae to 0.025ml/ml of CP along with 1, 5 and 10 mg/ml of curcumin results in the dose dependent significant decrease in the <em>hsp70</em> expression and tissue damage for 12, 24 and 48hr of duration. Similar results were obtained with the exposure of third instar larvae to 0.050 ml/ml of CP along with 1, 5 and 10 mg/ml of curcumin. The selected doses of curcumin i.e. 1, 5 and 10 mg/ml were not toxic but reduced significantly the expression of <em>hsp70</em> and tissue damage induced by CP. The results of the present study suggest that the curcumin has a protective role against the toxic effects of CP in the third instar larvae of transgenic <em>Drosophila melanogaster (hsp70-lacZ)Bg9</em>.

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