scholarly journals Diverse cellular actions of tert-butylhydroquinone, a food additive, on rat thymocytes

2017 ◽  
Vol 6 (6) ◽  
pp. 922-929 ◽  
Author(s):  
Norio Kamemura ◽  
Keisuke Oyama ◽  
Kaori Kanemaru ◽  
Kumio Yokoigawa ◽  
Yasuo Oyama

Tertiary butylhydroquinone (TBHQ) is a food additive that possesses antioxidant activity.

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Kyoko Kofuji ◽  
Ayumi Aoki ◽  
Kazufumi Tsubaki ◽  
Masanori Konishi ◽  
Takashi Isobe ◽  
...  

β-Glucans extracted from barley, which mainly contains β-(1,3-1,4)-D-glucan, are used extensively as supplements and food additives due to their wide biologic activities, including a reduction in blood lipid level. In this study, the antioxidant activity of β-glucan was examined to assess potential new benefits associated with β-glucan, because oxidative stress is considered one of the primary causal factors for various diseases and aging. β-Glucan extracted from barley was found to possess significant antioxidant activity. The amount of antioxidant activity was influenced by different physiologic properties (e.g., structure and molecular size) of β-glucan, which varied depending on the source and extraction method used. The antioxidant activity of β-glucan was significantly higher than that of various polymers that are used as food additives. These results indicate that β-glucan has promise as a polymeric excipient for supplement and food additive with antioxidant and other benefits, which may contribute to enhancing health and beauty.


2018 ◽  
Vol 260 ◽  
pp. 183-192 ◽  
Author(s):  
Hongyu Pu ◽  
Qiaomei Sun ◽  
Peixiao Tang ◽  
Ludan Zhao ◽  
Qi Li ◽  
...  

Antioxidants ◽  
2019 ◽  
Vol 8 (3) ◽  
pp. 76 ◽  
Author(s):  
Seung-Hyun Choi ◽  
Gill-Woong Jang ◽  
Sun-Il Choi ◽  
Tae-Dong Jung ◽  
Bong-Yeon Cho ◽  
...  

Antioxidants are used to prevent the oxidation of foods. When used for food additive purposes, the dosage should be regulated and the functionality evaluated to ensure stability. In this study, we performed a method validation for the quantitative analysis of rosemary extract residues and evaluated the antioxidant activity of rosemary extract in food matrices. The validated method was able to determine rosemary extract under the optimized high-performance liquid chromatography-photodiode array (HPLC-PDA) conditions. Furthermore, the antioxidant activity was evaluated by peroxide value, acid value, and in terms of the residual antioxidant levels in lard oil. For HPLC-PDA analysis, the limit of detection and quantification of rosemary extracts was ranged from 0.22 to 1.73 μg/mL, 0.66 to 5.23 μg/mL and the recoveries of the rosemary extracts ranged from 70.6 to 114.0%, with relative standard deviations of between 0.2% and 3.8%. In terms of antioxidant activity, carnosic acid performed better than carnosol. Furthermore, by evaluation of the residual antioxidant level using HPLC, we found that carnosic acid is more stable in lard oil than carnosol. These results indicate that rosemary extract can be used as an antioxidant and that the analytical method is suitable for the determination of rosemary extract in various food samples.


2017 ◽  
Vol 215 ◽  
pp. 101-107 ◽  
Author(s):  
Kyung-Min Park ◽  
Min Joo Lee ◽  
Su-Kyung Jo ◽  
Seung Jun Choi ◽  
JaeHwan Lee ◽  
...  

2018 ◽  
Vol 10 (3) ◽  
pp. 112 ◽  
Author(s):  
Yosophine Sulistyani ◽  
Steven Andrianto ◽  
Nani Indraswati ◽  
Aning Ayucitra

Phenolic compound extraction from peanut shell for natural anti-oxidant Peanut shell contains phenolic compounds which may be used as natural antioxidants. The content of polyphenols in peanut shells is around 3.34-7.13%. Antioxidants may inhibit the process of food damage caused by oxidation since they can counteract the free radicals. The purpose of this research was to study the effect of extraction temperature and extraction time on the yield, total phenolic content (TPC), and antioxidant activity of extracts. Antioxidant activity of extracts were compared to those of synthetic antioxidant TBHQ (tertiary butylhydroquinone). The results showed that the higher the temperature and the longer time of extraction results in the higher yield of extract, phenolic content, and also yield of phenolic. The yield increased to a certain level and then decreased. The highest yield of phenolic (0.6534 g GAE/100 g peanut shell) was obtained at extraction temperature of 70 oC for 105 minutes. The antioxidant activity of extract also comparable to those of synthetic antioxidant TBHQ which was 97.98%. Keywords: peanut shell, antioxidants, phenolic compounds AbstrakKulit kacang mengandung senyawa fenolik yang bersifat antioksidan. Kandungan polifenol dalam kulit kacang sekitar 3,34-7,13%, oleh sebab itu kulit kacang tanah dapat diolah lebih lanjut sebagai sumber antioksidan alami. Antioksidan dapat menghambat proses kerusakan bahan pangan yang disebabkan oleh proses oksidasi dan mampu menangkal radikal bebas. Tujuan dari penelitian ini adalah untuk mempelajari pengaruh suhu dan waktu ekstraksi terhadap perolehan, kadar senyawa fenolik dan aktivitas antioksidan dalam proses ekstraksi senyawa fenolik dari kulit kacang tanah. Suhu dan waktu ekstraksi yang optimum ditentukan dari perolehan senyawa fenolik yang terbesar. Dalam penelitian ini, aktivitas antioksidan dari ekstrak dibandingkan terhadap aktivitas antioksidan sintetis TBHQ (tertiary butylhydroquinone). Berdasarkan hasil penelitian didapatkan bahwa semakin tinggi suhu dan semakin lama waktu ekstraksi maka dihasilkan perolehan ekstrak, kadar senyawa fenolik, dan perolehan fenolik yang semakin tinggi. Perolehan akan meningkat sampai batas tertentu kemudian mengalami penurunan. Ekstrak kulit kacang dengan perolehan fenolik terbesar (0,6534 g GAE/100 g kulit kacang) diperoleh pada proses ekstraksi dengan kondisi suhu ekstraksi 70 oC dan waktu ekstraksi 105 menit. Aktivitas antioksidan dari ekstrak tersebut hampir menyamai aktivitas antioksidan sintetis TBHQ yaitu sebesar 97,98%.Kata kunci: kulit kacang tanah, antioksidan, senyawa fenolik


2014 ◽  
Vol 65 (2) ◽  
pp. e016 ◽  
Author(s):  
X. C. Weng ◽  
Z. W. Jiang ◽  
Y. Huang ◽  
J. P. Hou ◽  
X. Y. Liao

LWT ◽  
2022 ◽  
Vol 154 ◽  
pp. 112574
Author(s):  
Qian Li ◽  
Jing Li ◽  
Mengran Duan ◽  
Lu Liu ◽  
Yinxin Fu ◽  
...  

2017 ◽  
Vol 87 (3-4) ◽  
pp. 191-200 ◽  
Author(s):  
Nidhal Soualeh ◽  
Aliçia Stiévenard ◽  
Elie Baudelaire ◽  
Rachid Soulimani ◽  
Jaouad Bouayed

Abstract. In this study, cytoprotective and antioxidant activities of Rosa canina (RC) and Salix alba (SA), medicinal plants, were studied on mouse primary splenocytes by comparing Controlled Differential Sieving process (CDSp), which is a novel green solvent-free process, versus a conventional technique, employing hydroethanolic extraction (HEE). Thus, preventive antioxidant activity of three plant powders of homogeneous particle sizes, 50–100 µm, 100–180 µm and 180–315 µm, dissolved directly in the cellular buffer, were compared to those of hydroethanolic (HE) extract, at 2 concentrations (250 and 500 µg/mL) in H2O2-treated spleen cells. Overall, compared to HE extract, the superfine powders, i. e., fractions < 180 µm, at the lowest concentration, resulted in greater reactive oxygen species (ROS) elimination, increased glutathione peroxidase (GPx) activity and lower malondialdehyde (MDA) production. Better antioxidant and preventive effects in pre-treated cells were found with the superfine powders for SA (i. e., 50–100 µm and 100–180 µm, both p < 0.001), and with the intermediate powder for RC (i. e., 100–180 µm, p < 0.05) versus HE extract. The activity levels of catalase (CAT) and superoxide dismutase (SOD) in pretreated splenocytes exposed to H2O2, albeit reduced, were near to those in unexposed cells, suggesting that pretreatment with the fine powders has relatively restored the normal levels of antioxidant-related enzymes. These findings supported that CDSp improved the biological activities of plants, avoiding the use of organic solvents and thus it could be a good alternative to conventional extraction techniques.


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