SIRT1 attenuated oxidative stress induced by methyl tert-butyl ether in HT22 cells
Keyword(s):
Methyl tertiary-butyl ether (MTBE), an unleaded gasoline additive, can lead to oxidative stress and then injury to the nervous system after long-term exposure. SIRT1, a NAD+-dependent histone deacetylase, can play a neuroprotective role in brain injury induced by MTBE.