Near infrared photothermal-responsive poly(vinyl alcohol)/black phosphorus composite hydrogels with excellent on-demand drug release capacity

2018 ◽  
Vol 6 (11) ◽  
pp. 1622-1632 ◽  
Author(s):  
Guanghui Yang ◽  
Xuejuan Wan ◽  
Zhipeng Gu ◽  
Xierong Zeng ◽  
Jiaoning Tang
Keyword(s):  
Mechanical Properties ◽  
Drug Release ◽  
Vinyl Alcohol ◽  
Near Infrared ◽  
Black Phosphorus ◽  
Poly Vinyl Alcohol ◽  
Composite Hydrogels ◽  
On Demand ◽  
Release Capacity ◽  
Good Biocompatibility

Novel PVA/pBP hydrogels with highly effective NIR-responsive drug release performance, robust mechanical properties and good biocompatibility were prepared.

scholarly journals Novel Hydrogels of Chitosan and Poly (vinyl alcohol) Reinforced with Inorganic Particles of Bioactive Glass

Polymers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 691
Author(s):  
O. Sánchez-Aguinagalde ◽  
Ainhoa Lejardi ◽  
Emilio Meaurio ◽  
Rebeca Hernández ◽  
Carmen Mijangos ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Drug Release ◽  
Bioactive Glass ◽  
Vinyl Alcohol ◽  
Release Kinetics ◽  
The Body ◽  
Poly Vinyl Alcohol ◽  
X Ray Diffraction ◽  
Inorganic Particles ◽  
Release Studies

Chitosan (CS) and poly (vinyl alcohol) (PVA) hydrogels, a polymeric system that shows a broad potential in biomedical applications, were developed. Despite the advantages they present, their mechanical properties are insufficient to support the loads that appear on the body. Thus, it was proposed to reinforce these gels with inorganic glass particles (BG) in order to improve mechanical properties and bioactivity and to see how this reinforcement affects levofloxacin drug release kinetics. Scanning electron microscopy (SEM), X-ray diffraction (XRD), swelling tests, rheology and drug release studies characterized the resulting hydrogels. The experimental results verified the bioactivity of these gels, showed an improvement of the mechanical properties and proved that the added bioactive glass does affect the release kinetics.

scholarly journals Fabrication of photothermally active poly(vinyl alcohol) films with gold nanostars for antibacterial applications

2018 ◽  
Vol 9 ◽  
pp. 2040-2048 ◽  
Author(s):  
Mykola Borzenkov ◽  
Maria Moros ◽  
Claudia Tortiglione ◽  
Serena Bertoldi ◽  
Nicola Contessi ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Vinyl Alcohol ◽  
Near Infrared ◽  
Polymeric Materials ◽  
Photothermal Effect ◽  
Poly Vinyl Alcohol ◽  
Broad Application ◽  
Gold Nanostars ◽  
Wide Range ◽  
Spherical Gold Nanoparticles

The unique photothermal properties of non-spherical gold nanoparticles under near-infrared (NIR) irradiation find broad application in nanotechnology and nanomedicine. The combination of their plasmonic features with widely used biocompatible poly(vinyl alcohol) (PVA) films can lead to novel hybrid polymeric materials with tunable photothermal properties and a wide range of applications. In this study, thin PVA films containing highly photothermally efficient gold nanostars (GNSs) were fabricated and their properties were studied. The resulting films displayed good mechanical properties and a pronounced photothermal effect under NIR irradiation. The local photothermal effect triggered by NIR irradiation of the PVA-GNS films is highly efficient at killing bacteria, therefore providing an opportunity to develop new types of protective antibacterial films and coatings.

Electrospun electroactive nanofibers of gelatin‐oligoaniline/Poly (vinyl alcohol) templates for architecting of cardiac tissue with on‐demand drug release

2019 ◽  
Vol 30 (6) ◽  
pp. 1473-1483 ◽  
Author(s):  
Shahrokh Shojaie ◽  
Mostafa Rostamian ◽  
Ali Samadi ◽  
Mohammad Amin Sabbagh Alvani ◽  
Hossein Ali Khonakdar ◽  
...  
Keyword(s):  
Drug Release ◽  
Vinyl Alcohol ◽  
Cardiac Tissue ◽  
Poly Vinyl Alcohol ◽  
On Demand

scholarly journals Fabrication of Hybrid Nanofibers from Biopolymers and Poly (Vinyl Alcohol)/Poly (ε-Caprolactone) for Wound Dressing Applications

Polymers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 2104
Author(s):  
Sibusiso Alven ◽  
Blessing Atim Aderibigbe
Keyword(s):  
Mechanical Properties ◽  
Wound Healing ◽  
Vinyl Alcohol ◽  
Wound Dressing ◽  
Chronic Wounds ◽  
Cellular Adhesion ◽  
Wound Dressings ◽  
Poly Vinyl Alcohol ◽  
High Porosity ◽  
Hybrid Nanofibers

The management of chronic wounds is challenging. The factors that impede wound healing include malnutrition, diseases (such as diabetes, cancer), and bacterial infection. Most of the presently utilized wound dressing materials suffer from severe limitations, including poor antibacterial and mechanical properties. Wound dressings formulated from the combination of biopolymers and synthetic polymers (i.e., poly (vinyl alcohol) or poly (ε-caprolactone) display interesting properties, including good biocompatibility, improved biodegradation, good mechanical properties and antimicrobial effects, promote tissue regeneration, etc. Formulation of these wound dressings via electrospinning technique is cost-effective, useful for uniform and continuous nanofibers with controllable pore structure, high porosity, excellent swelling capacity, good gaseous exchange, excellent cellular adhesion, and show a good capability to provide moisture and warmth environment for the accelerated wound healing process. Based on the above-mentioned outstanding properties of nanofibers and the unique properties of hybrid wound dressings prepared from poly (vinyl alcohol) and poly (ε-caprolactone), this review reports the in vitro and in vivo outcomes of the reported hybrid nanofibers.

Preparation of Polyurethane-Poly (Vinyl Alcohol) / Chitosan Blend Nanofiber Nonwovens by Coelectrospinning

2012 ◽  
Vol 602-604 ◽  
pp. 157-160
Author(s):  
Wei Min Kang ◽  
Jing Yan ◽  
Bo Wen Cheng
Keyword(s):  
Mechanical Properties ◽  
Vinyl Alcohol ◽  
Diameter Distribution ◽  
Poly Vinyl Alcohol ◽  
Technical Parameters ◽  
The Ideal

Polyurethane-poly (vinyl alcohol)/chitosan (PU-PVA/CS) blend nanofiber nonwovens were successfully prepared by coelectrospinning in this paper. The morphology, diameter and structure of the electrospun nanomaterials were examined by SEM and FITR, and their mechanical properties were tested. The diameter distribution of the nanofibers was measured by Image-Pro Plus. The results show that the ideal nanofibers with the diameter in 50-350 nm can be obtained with the proper technical parameters of PU and PVA/CS nanofibers as follows: the spinning voltage at 30 kV and 40 kV, the extruding speed at 6 mL/h and 0.5 ml/h, the collecting distance at 150 mm and 200 mm, respectively.

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