Enzyme-instructed self-assembly leads to the activation of optical properties for selective fluorescence detection and photodynamic ablation of cancer cells

2018 ◽  
Vol 6 (17) ◽  
pp. 2566-2573 ◽  
Author(s):  
Shenglu Ji ◽  
Heqi Gao ◽  
Wancen Mu ◽  
Xiang Ni ◽  
Xiaoyong Yi ◽  
...  

An aggregation-induced emission luminogen (AIEgen)-based probe with both fluorescence and photoactivity activatable characteristics is developed for cancer theranostics.

2021 ◽  
Author(s):  
Shenglan Wang ◽  
Chong-Hua Zhang ◽  
Peisheng Zhang ◽  
Shu Chen ◽  
Zhi-ling Song ◽  
...  

Aggregation induced emission (AIE) dots have gained broad attention in fluorescence bioimaging and biosensor in virtue of their distinctive optical properties of splendid biocompatibility, high brightness and good photostability. However,...


2017 ◽  
Vol 136 ◽  
pp. 898-908 ◽  
Author(s):  
Jaroslaw Piskorz ◽  
Sebastian Lijewski ◽  
Mateusz Gierszewski ◽  
Karolina Gorniak ◽  
Lukasz Sobotta ◽  
...  

2019 ◽  
Vol 20 (8) ◽  
pp. 1891 ◽  
Author(s):  
Jianxing Wang ◽  
Xiangfang Lin ◽  
Tong Shu ◽  
Lei Su ◽  
Feng Liang ◽  
...  

Aggregation-induced emission (AIE) is an intriguing strategy to enhance the luminescence of metal nanoclusters (NCs). However, the morphologies of aggregated NCs are often irregular and inhomogeneous, leading to instability and poor color purity of the aggregations, which greatly limit their further potential in optical applications. Inspired by self-assembly techniques, manipulating metal NCs into well-defined architectures has achieved success. The self-assembled metal NCs often exhibit enhancing emission stability and intensity compared to the individually or randomly aggregated ones. Meanwhile, the emission color of metal NCs becomes tunable. In this review, we summarize the synthetic strategies involved in self-assembly of metal NCs for the first time. For each synthetic strategy, we describe the self-assembly mechanisms involved and the dependence of optical properties on the self-assembly. Finally, we outline the current challenges to and perspectives on the development of this area.


2015 ◽  
Vol 51 (92) ◽  
pp. 16494-16497 ◽  
Author(s):  
Wenjiao Zhou ◽  
Daxiu Li ◽  
Yaqin Chai ◽  
Ruo Yuan ◽  
Yun Xiang

MicroRNA triggered catalytic self-assembly of DNA nanostructures enables highly sensitive fluorescence detection of microRNA from human breast cancer cells.


2003 ◽  
Vol 771 ◽  
Author(s):  
Pavel I. Lazarev ◽  
Michael V. Paukshto ◽  
Elena N. Sidorenko

AbstractWe report a new method of Thin Crystal Film deposition. In the present paper we describe the method of crystallization, structure, and optical properties of Bisbenzimidazo[2,1-a:1',2',b']anthra[2,1,9-def:6,5,10-d'e'f']-diisoquinoline-6,9-dion (mixture with cis-isomer) (abbreviated DBI PTCA) sulfonation product. The Thin Crystal Film has a thickness of 200-1000 nm, with anisotropic optical properties such as refraction and absorption indices. X-ray diffraction data evidences a lyotropic liquid crystalline state in liquid phase and crystalline state in solid film. Anisotropic optical properties of the film make it useful in optical devices, e.g. liquid crystal displays.


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