Nano-functionalized long-period fiber grating probe for disease-specific protein detection

2018 ◽  
Vol 6 (3) ◽  
pp. 386-392 ◽  
Author(s):  
Deependra Tyagi ◽  
Satyendra Kumar Mishra ◽  
Bing Zou ◽  
Congcong Lin ◽  
Ting Hao ◽  
...  
Keyword(s):  
Real Time ◽  
Protein Detection ◽  
Specific Protein ◽  
Fiber Grating ◽  
Label Free ◽  
Long Period Fiber Grating ◽  
Long Period ◽  
Specific Proteins ◽  
Period Fiber Grating ◽  
Disease Specific

Label-free nano-functionalized LPFG based real-time, reusable sensor for sensitive detection of disease-specific proteins.

Real-Time and Sensitive Immunosensor for Label-Free Detection of Specific Antigen with a Comb of Microchannel Long-Period Fiber Grating

2020 ◽  
Vol 92 (24) ◽  
pp. 15989-15996
Author(s):  
Hsin-Yi Wen ◽  
Sheng-Feng Wang ◽  
Chien-Hsing Li ◽  
Yao-Tsung Yeh ◽  
Chia-Chin Chiang
Keyword(s):  
Real Time ◽  
Specific Antigen ◽  
Fiber Grating ◽  
Label Free ◽  
Long Period Fiber Grating ◽  
Long Period ◽  
Label Free Detection ◽  
Period Fiber Grating

Dual‐peak long period fiber grating coated with graphene oxide for label‐free and specific assays of H5N1 virus

2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Binbin Luo ◽  
Zhijiang Liu ◽  
Xin Wang ◽  
Shenghui Shi ◽  
Nianbing Zhong ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
H5n1 Virus ◽  
Fiber Grating ◽  
Label Free ◽  
Long Period Fiber Grating ◽  
Long Period ◽  
Period Fiber Grating

Label-free cocaine aptasensor based on a long-period fiber grating

2019 ◽  
Vol 44 (10) ◽  
pp. 2482 ◽  
Author(s):  
Anna Celebanska ◽  
Yasser Chiniforooshan ◽  
Monika Janik ◽  
Predrag Mikulic ◽  
Balasubramanian Sellamuthu ◽  
...  
Keyword(s):  
Fiber Grating ◽  
Label Free ◽  
Long Period Fiber Grating ◽  
Long Period ◽  
Period Fiber Grating

scholarly journals Label-free oligonucleotide biosensor based on dual-peak long period fiber grating

2016 ◽  
Author(s):  
Xianfeng Chen ◽  
Chen Liu ◽  
Marcos R. Cardoso ◽  
Cleber R. Mendonça ◽  
David A. Nagel ◽  
...  
Keyword(s):  
Fiber Grating ◽  
Label Free ◽  
Long Period Fiber Grating ◽  
Long Period ◽  
Period Fiber Grating

scholarly journals Realization of Enhanced Evanescent Field Long Period Fiber Grating near Turn around Point for Label-Free Immunosensing

Proceedings ◽  
2020 ◽  
Vol 60 (1) ◽  
pp. 9
Author(s):  
Tanoy Kumar Dey ◽  
Sara Tombelli ◽  
Palas Biswas ◽  
Ambra Giannetti ◽  
Nandini Basumallick ◽  
...  
Keyword(s):  
Immunoglobulin G ◽  
Flow Cell ◽  
Evanescent Field ◽  
Fiber Grating ◽  
Label Free ◽  
Maximum Enhancement ◽  
Long Period Fiber Grating ◽  
Long Period ◽  
Cladding Mode ◽  
Period Fiber Grating

A long-period fiber grating (LPFG) with maximum enhancement of evanescent field has been designed and fabricated, along with theoretical modeling, by working near the turn-around point (TAP) of the lowest order symmetric cladding mode (LP0.2 cladding mode). The LPFG was fabricated using a point-by-point inscription technique and it was characterized in terms of surrounding refractive index (SRI) within the range of 1.333 to 1.3335 using a thermostated flow-cell. This closed cell, made of poly(methyl methacrylate) (PMMA), was designed for better handling of the sensor, because during the fabrication process, the diameter of the LPFG was reduced up to ~20 µm by chemical etching, for the maximum enhancement of the evanescent field. The sensitivity of dual peak resonance of the LP0.2 cladding mode near TAP was measured and resulted to be ~8751 nm/SRIU with a resolution of the order of 10−5 RIU. The sensor was further used for the label-free immunosensing application by the implementation of Immunoglobulin G (IgG)/anti-Immunoglobulin G (anti-IgG) bioassay in human serum on the grating region inside the thermostated closed flow cell.

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