Site-specific sonocatalytic tumor suppression by chemically engineered single-crystalline mesoporous titanium dioxide sonosensitizers

2017 ◽  
Vol 5 (24) ◽  
pp. 4579-4586 ◽  
Author(s):  
Xi Wang ◽  
Wenping Wang ◽  
Luodan Yu ◽  
Yang Tang ◽  
Jiaying Cao ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Mesoporous Silica ◽  
Tumor Suppression ◽  
Site Specific ◽  
Single Crystalline ◽  
Dynamic Therapy ◽  
Mesoporous Titanium Dioxide

Mesoporous silica nanocrystals have been developed as sonosensitizers for efficient dynamic therapy of tumors.

scholarly journals Anodic Titanium Dioxide Nanotubes for Magnetically Guided Therapeutic Delivery

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Morteza Hasanzadeh Kafshgari ◽  
Delf Kah ◽  
Anca Mazare ◽  
Nhat Truong Nguyen ◽  
Monica Distaso ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Hela Cells ◽  
Release Kinetics ◽  
Drug Loading ◽  
Oxide Nanoparticles ◽  
Site Specific ◽  
Therapeutic Drugs ◽  
Wide Range

Abstract Hollow titanium dioxide (TiO2) nanotubes offer substantially higher drug loading capacity and slower drug release kinetics compared to solid drug nanocarriers of comparable size. In this report, we load TiO2 nanotubes with iron oxide nanoparticles to facilitate site-specific magnetic guidance and drug delivery. We generate magnetic TiO2 nanotubes (TiO2NTs) by incorporating a ferrofluid containing Ø ≈ 10 nm iron oxide nanoparticles in planar sheets of weakly connected TiO2 nanotubes. After thermal annealing, the magnetic tubular arrays are loaded with therapeutic drugs and then sonicated to separate the nanotubes. We demonstrate that magnetic TiO2NTs are non-toxic for HeLa cells at therapeutic concentrations (≤200 µg/mL). Adhesion and endocytosis of magnetic nanotubes to a layer of HeLa cells are increased in the presence of a magnetic gradient field. As a proof-of-concept, we load the nanotubes with the topoisomerase inhibitor camptothecin and achieve a 90% killing efficiency. We also load the nanotubes with oligonucleotides for cell transfection and achieve 100% cellular uptake efficiency. Our results demonstrate the potential of magnetic TiO2NTs for a wide range of biomedical applications, including site-specific delivery of therapeutic drugs.

Potassium and iodide codoped mesoporous titanium dioxide for enhancing photocatalytic degradation of phenolic compounds

2021 ◽  
Vol 767 ◽  
pp. 138367
Author(s):  
Hengjun Gai ◽  
Haozhong Wang ◽  
Lei Liu ◽  
Bingxiao Feng ◽  
Meng Xiao ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Phenolic Compounds ◽  
Photocatalytic Degradation ◽  
Mesoporous Titanium Dioxide

Synthesis and photoelectrochemical studies of N, Zr co-doped mesoporous titanium dioxide

2015 ◽  
Vol 736 ◽  
pp. 93-100 ◽  
Author(s):  
Haijin Liu ◽  
Sapanbir S. Thind ◽  
Guosheng Wu ◽  
Jiali Wen ◽  
Aicheng Chen
Keyword(s):  
Titanium Dioxide ◽  
Mesoporous Titanium Dioxide ◽  
Photoelectrochemical Studies ◽  
Co Doped

Low-Symmetry Mesoporous Titanium Dioxide (lsm-TiO2) Electrocatalyst for Efficient and Durable Oxygen Evolution in Aqueous Alkali

2018 ◽  
Vol 165 (7) ◽  
pp. H300-H309 ◽  
Author(s):  
Mabrook S. Amer ◽  
Mohamed A. Ghanem ◽  
Abdullah M. Al-Mayouf ◽  
Prabhakarn Arunachalam
Keyword(s):  
Titanium Dioxide ◽  
Oxygen Evolution ◽  
Aqueous Alkali ◽  
Mesoporous Titanium Dioxide ◽  
Low Symmetry

A drastic improvement in photocatalytic H2 production by TiO2 nanosheets grown directly on Ta2O5 substrates

Nanoscale ◽  
2021 ◽  
Author(s):  
Benedict Osuagwu ◽  
Waseen Raza ◽  
Alexander Tesler ◽  
Patrik Schmuki
Keyword(s):  
Titanium Dioxide ◽  
Water Splitting ◽  
H2 Production ◽  
Single Crystalline ◽  
Photocatalytic Water Splitting ◽  
Semiconducting Material ◽  
Tio2 Nanosheets ◽  
Photocatalytic Applications

Titanium dioxide (TiO2) is the most frequently studied semiconducting material for photocatalytic water splitting. One of the favored forms of TiO2 for photocatalytic applications is layers of erected single-crystalline anatase...

Adsorption of Sr(II) cations onto phosphated mesoporous titanium dioxide: Mechanism, isotherm and kinetics studies

2019 ◽  
Vol 7 (6) ◽  
pp. 103430 ◽  
Author(s):  
Ivan Mironyuk ◽  
Tetiana Tatarchuk ◽  
Hanna Vasylyeva ◽  
Mu. Naushad ◽  
Igor Mykytyn
Keyword(s):  
Titanium Dioxide ◽  
Kinetics Studies ◽  
Mesoporous Titanium Dioxide

Mesoporous titanium dioxide: sonochemical synthesis and application in dye-sensitized solar cells

2001 ◽  
Vol 11 (2) ◽  
pp. 521-526 ◽  
Author(s):  
Yang-Qin Wang ◽  
Si-Guang Chen ◽  
Xiang-Hai Tang ◽  
Oleg Palchik ◽  
Arie Zaban ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Solar Cells ◽  
Dye Sensitized Solar Cells ◽  
Sonochemical Synthesis ◽  
Dye Sensitized ◽  
Mesoporous Titanium Dioxide ◽  
Sensitized Solar Cells
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