A reversible ratiometric two-photon lysosome-targeted probe for real-time monitoring of pH changes in living cells

2017 ◽  
Vol 5 (24) ◽  
pp. 4768-4773 ◽  
Author(s):  
Weifang Luo ◽  
Huie Jiang ◽  
Xiaoliang Tang ◽  
Weisheng Liu
Keyword(s):  
Real Time ◽  
Living Cells ◽  
Real Time Monitoring ◽  
Ph Changes ◽  
Two Photon

A reversible ratiometric two-photon lysosome-targeted probe that can monitor real-time pH changes in living cells.

Real-time monitoring of intracellular nitric oxide using a long-wavelength-emitting probe via one-photon or two-photon excitation

2019 ◽  
Vol 7 (11) ◽  
pp. 3246-3252 ◽  
Author(s):  
Changquan Tang ◽  
Mingxue Wang ◽  
Xiaoying Shang ◽  
Xueyuan Chen ◽  
Deguang Huang ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Real Time ◽  
Living Cells ◽  
Real Time Monitoring ◽  
Long Wavelength ◽  
Two Photon ◽  
Turn On ◽  
Photon Excitation ◽  
Endogenous Nitric Oxide ◽  
Two Photon Excitation

A long-wavelength-emitting fluorescent turn-on probe is developed for monitoring exogenous or endogenous nitric oxide in living cells.

A bright two-photon fluorescent probe for real-time monitoring autophagy in living cells

2020 ◽  
Vol 31 (2) ◽  
pp. 447-450 ◽  
Author(s):  
Chuankun Jiang ◽  
Longchun Li ◽  
Jiacheng Jiang ◽  
Lilin Hou ◽  
Gemin Fang ◽  
...  
Keyword(s):  
Real Time ◽  
Fluorescent Probe ◽  
Living Cells ◽  
Real Time Monitoring ◽  
Two Photon

A multicolor DNA tetrahedron nanoprobe for analyzing human telomerase in living cells

2021 ◽  
Author(s):  
Ruiyuan Zhang ◽  
Ruixue Zhang ◽  
Wei Jiang ◽  
Xiaowen Xu
Keyword(s):  
Real Time ◽  
Length Distribution ◽  
Telomerase Activity ◽  
Living Cells ◽  
Real Time Monitoring ◽  
Dna Tetrahedron ◽  
Human Telomerase

A sequentially lighting-up multicolor DNA tetrahedron nanoprobe is constructed for imaging telomerase activity, real-time monitoring telomerase action and determining product length distribution in living cells.

A novel microfluidic microelectrode chip for a significantly enhanced monitoring of NPY-receptor activation in live mode

Lab on a Chip ◽  
2017 ◽  
Vol 17 (24) ◽  
pp. 4294-4302 ◽  
Author(s):  
Franziska D. Zitzmann ◽  
Heinz-Georg Jahnke ◽  
Felix Nitschke ◽  
Annette G. Beck-Sickinger ◽  
Bernd Abel ◽  
...  
Keyword(s):  
Real Time ◽  
Microfluidic Chip ◽  
Microelectrode Array ◽  
Fem Simulation ◽  
Receptor Activation ◽  
Living Cells ◽  
Real Time Monitoring ◽  
Non Invasive ◽  
Npy Receptor ◽  
Simulation Based

We present a FEM simulation based step-by-step development of a microelectrode array integrated into a microfluidic chip for the non-invasive real-time monitoring of living cells.

scholarly journals Designing, construction and characterization of genetically encoded FRET-based nanosensor for real time monitoring of lysine flux in living cells

2016 ◽  
Vol 14 (1) ◽  
Author(s):  
Seema Ameen ◽  
Mohammad Ahmad ◽  
Mohd. Mohsin ◽  
M. Irfan Qureshi ◽  
Mohamed M. Ibrahim ◽  
...  
Keyword(s):  
Real Time ◽  
Living Cells ◽  
Real Time Monitoring

A water-soluble benzoxazole-based probe: Real-time monitoring PPi via situ reaction by two-photon cells imaging

Talanta ◽  
2019 ◽  
Vol 195 ◽  
pp. 158-164 ◽  
Author(s):  
Dan Liu ◽  
Sheng Liu ◽  
Xinyu Zhang ◽  
Qiong Zhang ◽  
Jianhua Yu ◽  
...  
Keyword(s):  
Real Time ◽  
Water Soluble ◽  
Real Time Monitoring ◽  
Two Photon

scholarly journals NIR-Responsive Lysosomotropic Phototrigger: ʽAIE + ESIPTʼ Active Naphthalene Based Single Component Photoresponsive Nanocarrier with Two-Photon Uncaging and Real-Time Monitoring Ability

2021 ◽  
Author(s):  
Biswajit Roy ◽  
Rakesh Mengji ◽  
Samrat Roy ◽  
Bipul Pal ◽  
Avijit Jana ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Real Time ◽  
Near Infrared ◽  
Single Component ◽  
Photon Absorption ◽  
Real Time Monitoring ◽  
Two Photon ◽  
Nir Light

In recent times, organelle-targeted drug delivery systems gained tremendous attention due to the site specific delivery of active drug molecules resulting in enhanced bioefficacy. In this context, the phototriggered drug delivery system (DDS) for releasing an active molecule is superior as it provides spatial and temporal control over the release. So far, near infrared (NIR) light responsive organelle targeted DDS has not yet been developed. Hence, we introduced a two-photon NIR-light responsive lysosome targeted ʽAIE + ESIPTʼ active single component DDS based on naphthalene chromophore. The Two-photon absorption cross-section of our DDS is 142 GM at 850 nm. The DDS was converted into pure organic nanoparticles for biological applications. Our nano-DDS is capable of selective targeting, AIE-luminogenic imaging, and drug release within the lysosome. In vitro studies using cancerous cell lines showed that our single component photoresponsive nanocarrier exhibited enhanced cytotoxicity and real-time monitoring ability of the drug release.

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