Facile preparation of pH/reduction dual-responsive prodrug nanohydrogels for tumor-specific intracellular triggered release with enhanced anticancer efficiency

2017 ◽  
Vol 5 (15) ◽  
pp. 2840-2848 ◽  
Author(s):  
Tingting Zhou ◽  
Xu Jia ◽  
Xubo Zhao ◽  
Jiagen Li ◽  
Peng Liu
Keyword(s):  
Triggered Release ◽  
Dual Responsive ◽  
Ph Reduction ◽  
Facile Preparation

Facile approach was developed for biocompatible and biodegradable pH/reduction dual-responsive nano-prodrug for tumor specific intracellular triggered release.

Oxidation and ATP dual-responsive block copolymer containing tertiary sulfoniums: self-assembly, protein complexation and triggered release

2021 ◽  
Author(s):  
Yanfen Jiang ◽  
Shuqi Dong ◽  
Guoyang Qin ◽  
Li Liu ◽  
Hanying Zhao
Keyword(s):  
Block Copolymer ◽  
Self Assembly ◽  
Phenylboronic Acid ◽  
Cationic Polymer ◽  
Release Profile ◽  
Triggered Release ◽  
Dual Responsive ◽  
Protein Complexation

Alkylation of thioether-containing block copolymer simultaneously incorporated sulfoniums and phenylboronic acid moieties. The co-assembly of this cationic polymer and protein generated micelles with an H2O2-and ATP-responsive release profile.

scholarly journals Rational design of drug delivery systems for potential programmable drug release and improved therapeutic effect

2019 ◽  
Vol 3 (6) ◽  
pp. 1159-1167 ◽  
Author(s):  
Yuxun Ding ◽  
Jinjian Liu ◽  
Xue Li ◽  
Linlin Xu ◽  
Chang Li ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Release ◽  
Therapeutic Effect ◽  
Drug Delivery Systems ◽  
Rational Design ◽  
Delivery Systems ◽  
Dual Responsive ◽  
Ph Reduction

pH-Reduction dual responsive nanocarriers (DRNs) achieve programmable release of CA4 and CDDP in cancer therapy.

Design of dual stimuli responsive polymer modified magnetic nanoparticles for targeted anti-cancer drug delivery and enhanced MR imaging

2016 ◽  
Vol 40 (1) ◽  
pp. 545-557 ◽  
Author(s):  
Dipsikha Bhattacharya ◽  
Birendra Behera ◽  
Sumanta Kumar Sahu ◽  
Rajakumar Ananthakrishnan ◽  
Tapas Kumar Maiti ◽  
...  
Keyword(s):  
Cancer Drug ◽  
Acidic Ph ◽  
Stimuli Responsive ◽  
Triggered Release ◽  
Dual Responsive ◽  
Anti Cancer ◽  
Responsive Polymer ◽  
Modified Magnetic Nanoparticles ◽  
Cancer Drug Delivery ◽  
Stimuli Responsive Polymer

Stimuli triggered release of DOX from dual responsive theranostic nanocarriers mimicking lysosomal conditions i.e. physiological temperature (37 °C) and acidic pH (5.5).

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