Bright luminescent optically engineered core/alloyed shell quantum dots: an ultrasensitive signal transducer for dengue virus RNA via localized surface plasmon resonance-induced hairpin hybridization

2017 ◽  
Vol 5 (16) ◽  
pp. 3047-3058 ◽  
Author(s):  
Oluwasesan Adegoke ◽  
Enoch Y. Park

A plasmon-mediated fluorescence molecular beacon biosensor probe has been developed for dengue virus with high sensitivity and specificity.

2020 ◽  
Vol 2 (2) ◽  
pp. 699-709 ◽  
Author(s):  
Ankan Dutta Chowdhury ◽  
Kenshin Takemura ◽  
Indra Memdi Khorish ◽  
Fahmida Nasrin ◽  
Mya Myat Ngwe Tun ◽  
...  

A fluorometric sensing system using LSPR phenomenon between fluorescent quantum dots and its adjacent AuNP to detect four closely related but serologically distinct dengue viruses (DENVs).


Nanomaterials ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 35
Author(s):  
Nur Afifah Ahmad Nazri ◽  
Nur Hidayah Azeman ◽  
Mohd Hafiz Abu Bakar ◽  
Nadhratun Naiim Mobarak ◽  
Yunhan Luo ◽  
...  

This paper demonstrates carbon quantum dots (CQDs) with triangular silver nanoparticles (AgNPs) as the sensing materials of localized surface plasmon resonance (LSPR) sensors for chlorophyll detection. The CQDs and AgNPs were prepared by a one-step hydrothermal process and a direct chemical reduction process, respectively. FTIR analysis shows that a CQD consists of NH2, OH, and COOH functional groups. The appearance of C=O and NH2 at 399.5 eV and 529.6 eV in XPS analysis indicates that functional groups are available for adsorption sites for chlorophyll interaction. A AgNP–CQD composite was coated on the glass slide surface using (3-aminopropyl) triethoxysilane (APTES) as a coupling agent and acted as the active sensing layer for chlorophyll detection. In LSPR sensing, the linear response detection for AgNP–CQD demonstrates R2 = 0.9581 and a sensitivity of 0.80 nm ppm−1, with a detection limit of 4.71 ppm ranging from 0.2 to 10.0 ppm. Meanwhile, a AgNP shows a linear response of R2 = 0.1541 and a sensitivity of 0.25 nm ppm−1, with the detection limit of 52.76 ppm upon exposure to chlorophyll. Based on these results, the AgNP–CQD composite shows a better linearity response and a higher sensitivity than bare AgNPs when exposed to chlorophyll, highlighting the potential of AgNP–CQD as a sensing material in this study.


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