A novel isophorone-based red-emitting fluorescent probe for selective detection of sulfide anions in water for in vivo imaging

2017 ◽  
Vol 5 (15) ◽  
pp. 2798-2803 ◽  
Author(s):  
Fangjun Huo ◽  
Yaqiong Zhang ◽  
Peng Ning ◽  
Xiangming Meng ◽  
Caixia Yin

A new red-emitting fluorescent probe for detection of sulfide anions in living cells (MCF-7 cells) and zebrafish was developed.

2015 ◽  
Vol 51 (15) ◽  
pp. 3143-3146 ◽  
Author(s):  
Hio-Ieng Un ◽  
Shuai Wu ◽  
Chang-Bo Huang ◽  
Zheng Xu ◽  
Lin Xu

A naphthalimide-based fluorescent probe for selectively detecting His in aqueous solution, living cells, andC. eleganshas been developed.


The Analyst ◽  
2018 ◽  
Vol 143 (2) ◽  
pp. 429-439 ◽  
Author(s):  
Xinyu Song ◽  
Xiaoyue Han ◽  
Fabiao Yu ◽  
Jinjin Zhang ◽  
Lingxin Chen ◽  
...  

A reversible fluorescent probe for the selective imaging of formaldehyde in living cells, tissues and in vivo.


Molecules ◽  
2019 ◽  
Vol 24 (18) ◽  
pp. 3328 ◽  
Author(s):  
Song Chen ◽  
Peng Hou ◽  
Jingwen Sun ◽  
Haijun Wang ◽  
Lei Liu

A new cyan fluorescent probe, MIPY-DNBS, using an imidazo[1,5-α]pyridine derivative as the fluorophore and 2,4-dinitrobenzensufonate as the recognition site for the selective detection of thiols (Cys, GSH, and Hcy), was designed and synthesized. Probe MIPY-DNBS exhibited a 172 nm Stokes shift, a fast response time (400 s), low cytotoxicity, low detection limits (12.7 nM for Cys), and excellent selectively in the detection of thiols. In addition, MIPY-DNBS was successfully applied to imaging thiols in living MCF-7 cells and zebrafish.


2014 ◽  
Vol 605 ◽  
pp. 19-22
Author(s):  
Hae Jo Kim

Two novel fluorescent chemodosimeters will be presented for the selective detection of cysteine over homocysteine and glutathione in aqueous solvent. First, a rhodamine-based fluorescent probe (1) will be reported. Masked with a para-hydroxybenzyl alcohol (HBA) unit, probe 1 initially showed a weak fluorescence but displayed a strong fluorescence through a series of reactions of Michael addition and intramolecular cyclization of cysteine, followed by deprotection of HBA. The caged probe (1) exhibited a selective and sensitive response toward cysteine over homocysteine and glutathione in HEPES buffer. Secondly, a fluorescein-based fluorescent probe will be discussed. A bromoacetyl functionalized fluorescein chemodosimeter (2) was utilized as a fluorescent probe for cysteine. The probe showed a selective and sensitive response to cysteine over homocysteine and glutathione in aqueous buffer through a rapid cyclization reaction. When cysteine was added, a fast fluorescence turn-on change of 2 was observed and applied to the in-vivo imaging of cysteine.


The Analyst ◽  
2015 ◽  
Vol 140 (13) ◽  
pp. 4576-4583 ◽  
Author(s):  
Ping Liu ◽  
Xiaotong Jing ◽  
Fabiao Yu ◽  
Changjun Lv ◽  
Lingxin Chen

We present a near-infrared fluorescent probe for the detection of nitroxyl (HNO) in living cells and in mice.


2016 ◽  
Vol 52 (51) ◽  
pp. 7982-7985 ◽  
Author(s):  
Lijuan Liang ◽  
Chang Liu ◽  
Xiaojie Jiao ◽  
Liancheng Zhao ◽  
Xianshun Zeng

A probe based on the phenothiazine–acridine orange conjugate (Ptz–AO) has been designed and synthesized for the sensitive and selective detection of HOCl.


2017 ◽  
Vol 53 (26) ◽  
pp. 3701-3704 ◽  
Author(s):  
Shahi Imam Reja ◽  
Muskan Gupta ◽  
Neha Gupta ◽  
Vandana Bhalla ◽  
Puja Ohri ◽  
...  

A lysosome targetable naphthalimide based fluorescent probe has been designed and synthesized for selective imaging of H2O2 in different cells, tissues and in vivo models.


Sign in / Sign up

Export Citation Format

Share Document