scholarly journals A novel restriction endonuclease GlaI for rapid and highly sensitive detection of DNA methylation coupled with isothermal exponential amplification reaction

2018 ◽  
Vol 9 (5) ◽  
pp. 1344-1351 ◽  
Author(s):  
Yueying Sun ◽  
Yuanyuan Sun ◽  
Weimin Tian ◽  
Chenghui Liu ◽  
Kejian Gao ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Restriction Endonuclease ◽  
Sensitivity And Specificity ◽  
Sensitive Detection ◽  
Site Specific ◽  
Highly Sensitive ◽  
Ultrahigh Sensitivity ◽  
Dna Methylations ◽  
Highly Sensitive Detection ◽  
Amplification Reaction

An elegant GlaI–EXPAR strategy is proposed which allows accurate detection of site-specific DNA methylations with ultrahigh sensitivity and specificity.

Nanoparticle-enabled highly sensitive detection of DNA methylation in single tube

2010 ◽  
Author(s):  
Tza-Huei “Jeff” Wang ◽  
Yi Zhang ◽  
Vasudev Bailey ◽  
Kristen L. Pelosky ◽  
Malcolm Brock ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Sensitive Detection ◽  
Single Tube ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

One-step detection of microRNA with high sensitivity and specificity via target-triggered loop-mediated isothermal amplification (TT-LAMP)

2017 ◽  
Vol 53 (80) ◽  
pp. 11040-11043 ◽  
Author(s):  
Yuanyuan Sun ◽  
Hui Tian ◽  
Chenghui Liu ◽  
Yueying Sun ◽  
Zhengping Li
Keyword(s):  
Sensitivity And Specificity ◽  
High Sensitivity ◽  
Isothermal Amplification ◽  
Sensitive Detection ◽  
Step Detection ◽  
Loop Mediated Isothermal Amplification ◽  
Highly Sensitive ◽  
One Step ◽  
Highly Sensitive Detection

A target-triggered loop-mediated isothermal amplification (TT-LAMP) mechanism is developed for simple one-step but highly sensitive detection of microRNAs.

Highly sensitive detection of DNA methylation levels by using a quantum dot-based FRET method

Nanoscale ◽  
2015 ◽  
Vol 7 (41) ◽  
pp. 17547-17555 ◽  
Author(s):  
Yunfei Ma ◽  
Honglian Zhang ◽  
Fangming Liu ◽  
Zhenhua Wu ◽  
Shaohua Lu ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Quantum Dot ◽  
Sensitive Detection ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

A quantum dot-based FRET method was established for a highly sensitive detection of DNA methylation levels.

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