scholarly journals Nickel-catalyzed transamidation of aliphatic amide derivatives

2017 ◽  
Vol 8 (9) ◽  
pp. 6433-6438 ◽  
Author(s):  
Jacob E. Dander ◽  
Emma L. Baker ◽  
Neil K. Garg
Keyword(s):  
Precious Metal ◽  
Metal Catalysis ◽  
Amide Derivatives ◽  
Precious Metal Catalysis ◽  
Aliphatic Amide

We report a two-step approach to achieve the transamidation of secondary aliphatic amides using non-precious metal catalysis.

scholarly journals Editorial: Special Issue Catalysis by Precious Metals, Past and Future

Catalysts ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 247
Author(s):  
Svetlana Ivanova ◽  
Marcela Martínez Tejada
Keyword(s):  
Precious Metal ◽  
Precious Metals ◽  
Special Issue ◽  
Metal Catalysis ◽  
Editorial Special Issue ◽  
Precious Metal Catalysis

Precious metal catalysis is often synonymous with diversity and versatility [...]

scholarly journals Activation of C–O and C–N Bonds Using Non-Precious-Metal Catalysis

ACS Catalysis ◽  
2020 ◽  
Vol 10 (20) ◽  
pp. 12109-12126 ◽  
Author(s):  
Timothy B. Boit ◽  
Ana S. Bulger ◽  
Jacob E. Dander ◽  
Neil K. Garg
Keyword(s):  
Precious Metal ◽  
Metal Catalysis ◽  
Precious Metal Catalysis

Recent advances in non-precious metal catalysis for oxygen-reduction reaction in polymer electrolyte fuelcells

2011 ◽  
Vol 4 (1) ◽  
pp. 114-130 ◽  
Author(s):  
Frédéric Jaouen ◽  
Eric Proietti ◽  
Michel Lefèvre ◽  
Régis Chenitz ◽  
Jean-Pol Dodelet ◽  
...  
Keyword(s):  
Oxygen Reduction Reaction ◽  
Oxygen Reduction ◽  
Polymer Electrolyte ◽  
Precious Metal ◽  
Reduction Reaction ◽  
Metal Catalysis ◽  
Recent Advances ◽  
Precious Metal Catalysis

Pentannulation of Heterocycles by Virtue of Precious Metal Catalysis

2015 ◽  
Vol 11 (5) ◽  
pp. 642-659 ◽  
Author(s):  
Martina Petrović ◽  
Ernesto G. Occhiato
Keyword(s):  
Precious Metal ◽  
Metal Catalysis ◽  
Precious Metal Catalysis

scholarly journals Spotlight on Non-Precious Metal Catalysis

2015 ◽  
Vol 19 (10) ◽  
pp. 1325-1326 ◽  
Author(s):  
Joshua R. Dunetz ◽  
Daniel Fandrick ◽  
Hans-Jürgen Federsel
Keyword(s):  
Precious Metal ◽  
Metal Catalysis ◽  
Precious Metal Catalysis

scholarly journals Design and Synthesis of Sustain-Acting Melatonin Prodrugs

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Phạm Văn Thoại ◽  
Nguyen Hai Nam
Keyword(s):  
Sustained Release ◽  
Human Plasma ◽  
Half Life ◽  
Plasma Model ◽  
Release Rates ◽  
Design And Synthesis ◽  
Amide Derivatives ◽  
Aliphatic Amide

Twelve melatonin amide prodrugs aiming at prolonging the action of melatoninin vivoby improving its half-life were designed and synthesized. Using an 80% human plasma model, it was found that the aliphatic amide derivatives were relatively stable and melatonin release from these compounds was not sufficient with melatonin release percentage. After 4-hour incubation with 80% human plasma, the melatonin release percentage achieved only approximately less than 20%. In contrast, the -succinyl and -glutaroylmelatonin derivatives (compounds11and12, resp.) were found to release melatonin in much higher rates. After 3-hour incubation in 80% human plasma, the melatonin release rates from11and12were found to be 67.3 and 75.6%, respectively. From these results, the -succinyl and -glutaroylmelatonin derivatives (compounds11and12) could be promising as sustained release prodrugs of melatonin.

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