scholarly journals Highly-sensitive detection of eight typical fluoroquinolone antibiotics by capillary electrophoresis-mass spectroscopy coupled with immunoaffinity extraction

RSC Advances ◽  
2018 ◽  
Vol 8 (8) ◽  
pp. 4063-4071 ◽  
Author(s):  
Xiao-Hui Zhang ◽  
Yan Deng ◽  
Ming-Zhe Zhao ◽  
Ying-Lin Zhou ◽  
Xin-Xiang Zhang
Keyword(s):  
Capillary Electrophoresis ◽  
Simultaneous Determination ◽  
Mass Spectroscopy ◽  
Water Samples ◽  
Environmental Water ◽  
Sensitive Detection ◽  
Fluoroquinolone Antibiotics ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

An off-line procedure, immunoaffinity extraction (IAE), followed by capillary electrophoresis-mass spectroscopy (CE-MS) has been developed for the simultaneous determination of eight typical FQs in environmental water samples.

Highly sensitive detection of copper(i) and copper(ii) in cell specimens by CE-UV with large-volume sample stacking

2016 ◽  
Vol 8 (21) ◽  
pp. 4272-4276 ◽  
Author(s):  
Cheng Chen ◽  
Xin Li ◽  
Xia Xie ◽  
Fengxia Chang ◽  
Meixian Li ◽  
...  
Keyword(s):  
Large Volume ◽  
Sensitive Detection ◽  
Sample Stacking ◽  
Highly Sensitive ◽  
Simultaneous Separation ◽  
Sensitive Determination ◽  
Highly Sensitive Detection ◽  
Determination Of Copper ◽  
Large Volume Sample Stacking

A CE-UV method has been developed for the simultaneous separation and sensitive determination of copper(i) and copper(ii) in cell specimens.

scholarly journals Fast UHPLC-MS/MS for the Simultaneous Determination of Azithromycin, Erythromycin, Fluoxetine and Sotalol in Surface Water Samples

2021 ◽  
Vol 11 (18) ◽  
pp. 8316
Author(s):  
Mira Azzi ◽  
Sylvain Ravier ◽  
Assem Elkak ◽  
Bruno Coulomb ◽  
Jean-Luc Boudenne
Keyword(s):  
Surface Water ◽  
Simultaneous Determination ◽  
Surface Waters ◽  
Water Samples ◽  
High Performance ◽  
Chemical Properties ◽  
Environmental Water ◽  
Butyl Ether ◽  
Flight Mass Spectrometry

Chromatographic development for the determination of pharmaceuticals in environmental water samples is particularly challenging when the analytes have significantly different physico-chemical properties (solubility, polarity, pKa) often requiring multiple chromatographic methods for each active component. This paper presents a method for the simultaneous determination of azithromycin, erythromycin (antibiotics), fluoxetine (anti-depressant) and sotalol (b-blocker) in surface waters by ultra-high-performance liquid chromatography coupled with ultra-high-resolution time-of-flight mass spectrometry. These pharmaceuticals—presenting a broad spectrum of polarity (0.24 ≤ log Kow ≤ 4.05)—were separated on a C-18 analytical column, after a simple filtration step for freshwater samples or after a liquid–liquid extraction with Methyl-tertio-butyl ether (MTBE) for seawater samples. The optimized separation method (in terms of nature of column and eluent, elution gradient, and of mass spectrometric parameters), enable one to reach limits of detection ranging between 2 and 7 ng L−1 and limits of quantification between 7 and 23 ng L−1 for the four targeted molecules, within a three minute run. This method was validated using samples collected from three different surface waters in Lebanon (freshwater and seawater) and analytical results were compared with those obtained in surface waters sampled in a French river, equivalent in terms of human activities. Using this method, we report the highest concentration of pharmaceuticals found in surface water (up to 377 ng L−1 and 268 ng L−1, respectively, for azithromycin and erythromycin, in the Litani river, Lebanon).

An evanescent wave multi-channel immunosensor system for the highly sensitive detection of small analytes in water samples

2014 ◽  
Vol 198 ◽  
pp. 150-156 ◽  
Author(s):  
Zhou Xiao-hong ◽  
Song Bao-dong ◽  
Shi Han-chang ◽  
Liu Lan-hua ◽  
Guo Hong-li ◽  
...  
Keyword(s):  
Water Samples ◽  
Evanescent Wave ◽  
Sensitive Detection ◽  
Highly Sensitive ◽  
Highly Sensitive Detection
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