scholarly journals Nonlinear oscillatory dynamics of the hardening of calcium phosphate bone cements

RSC Advances ◽  
2017 ◽  
Vol 7 (64) ◽  
pp. 40517-40532 ◽  
Author(s):  
Vuk Uskoković ◽  
Julietta V. Rau
Keyword(s):  
Phase Composition ◽  
Calcium Phosphate ◽  
Bone Cements ◽  
Oscillatory Dynamics ◽  
Calcium Phosphate Cements

Nonlinear, oscillatory dynamics was discovered in the evolution of phase composition during the setting of different calcium phosphate cements, two of which evolved toward brushite and one toward hydroxyapatite as the final product.

Therapy and regeneration-combined bone cements for minimally invasive treatment of neoplastic bone defects

2021 ◽  
Author(s):  
Yu Qu ◽  
Hui Zhuang ◽  
Meng Zhang ◽  
Yufeng Wang ◽  
Dong Zhai ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Minimally Invasive ◽  
Tumor Cells ◽  
Bone Tumor ◽  
Tumor Resection ◽  
Bone Defects ◽  
Bone Cements ◽  
Invasive Treatment ◽  
Calcium Phosphate Cements ◽  
Bone Tumor Resection

Although calcium phosphate cements (CPC) have been clinically used to repair bone defects caused by bone tumor resection, traditional CPC cannot kill the remaining tumor cells after surgery and prevent...

Dimensional and thermal behaviour of calcium phosphate cements during setting compared to PMMA bone cements

1995 ◽  
Vol 14 (1) ◽  
pp. 4-5 ◽  
Author(s):  
E. FernÁndez ◽  
M. P. Ginebra ◽  
O. Bermúdez ◽  
M. G. Boltong ◽  
F. C. M. Driessens ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Thermal Behaviour ◽  
Bone Cements ◽  
Calcium Phosphate Cements

scholarly journals Preparation, Structural Characterization, and Biomedical Applications of Gypsum-Based Nanocomposite Bone Cements

2021 ◽  
Author(s):  
Hesham F. El-Maghraby ◽  
Yaser E. Greish
Keyword(s):  
Mechanical Properties ◽  
Calcium Phosphate ◽  
Structural Characterization ◽  
Room Temperature ◽  
Bone Cements ◽  
Calcium Phosphate Cements ◽  
Metallic Implants ◽  
Hard Tissues ◽  
Subsequent Conversion ◽  
High Degree

Hard tissues are natural nanocomposites comprising collagen nanofibers that are interlocked with hydroxyapatite (HAp) nanocrystallites. This mechanical interlocking at the nanoscale provides the unique properties of hard tissues (bone and teeth). Upon fracture, cements are usually used for treatment of simple fractures or as an adhesive for the treatment of complicated fractures that require the use of metallic implants. Most of the commercially available bone cements are polymer-based, and lack the required bioactivity for a successful cementation. Besides calcium phosphate cements, gypsum is one of the early recognized and used biomaterials as a basi for a self-setting cementation. It is based on the controlled hydration of plaster of Paris at room temperature and its subsequent conversion to a self-setting solid gypsum product. In our work, we have taken this process further towards the development of a set of nanocomposites that have enhanced bioactivity and mechanical properties. This chapter will outline the formation, characterization, and properties of gypsum-based nanocomposites for bone cement applications. These modified cements can be formulated at room temperature and have been shown to possess a high degree of bioactivity, and are considered potential candidates for bone fracture and defect treatment.

Fast Setting Pre-Mixed Calcium Phosphate Bone Cements Based on α-Tricalcium Phosphate

2014 ◽  
Vol 604 ◽  
pp. 204-207 ◽  
Author(s):  
Zilgma Irbe ◽  
Guna Krieke ◽  
Kristine Salma-Ancane ◽  
Liga Berzina-Cimdina
Keyword(s):  
Compressive Strength ◽  
Liquid Phase ◽  
Calcium Phosphate ◽  
Tricalcium Phosphate ◽  
Aqueous Fluid ◽  
Dihydrogen Phosphate ◽  
Bone Cements ◽  
Polypropylene Glycol ◽  
Setting Reaction ◽  
Calcium Phosphate Cements

Conventional calcium phosphate bone cements are self setting water based pastes. Recently pre-mixed calcium phosphate bone cements have been proposed that have non-aqueous fluid as liquid phase of the paste. Such cements thus only start setting reaction in contact with body fluids. In this work the properties (cohesion, compressive strength, phase composition) of pre-mixed calcium phosphate cements based on α-tricalcium phosphate and calcium dihydrogen phosphate monohydrate are described. Properties of several cement compositions are examined and compared to properties of β-tricalcium phosphate and calcium dihydrogen phosphate monohydrate based cements. It was found that α-tricalcium phosphate and calcium dihydrogen phosphate monohydrate based cements have higher compressive strength (10 - 15 MPa) than corresponding β-tricalcium phosphate and calcium dihydrogen phosphate monohydrate based cements (10 - 6 MPa). Out of examined cement paste liquids (glycerol, polyethylene glycol and polypropylene glycol) cements using glycerol as the liquid phase had higher compressive strength and are more cohesive.

scholarly journals A review of calcium phosphate cements and acrylic bone cements as injectable materials for bone repair and implant fixation

2019 ◽  
Vol 17 (4) ◽  
pp. 228080001987259 ◽  
Author(s):  
Azizeh-Mitra Yousefi
Keyword(s):  
Calcium Phosphate ◽  
Minimally Invasive ◽  
Bone Repair ◽  
Unmet Need ◽  
Balloon Kyphoplasty ◽  
Healthcare Systems ◽  
Bone Cements ◽  
Implant Fixation ◽  
Calcium Phosphate Cements ◽  
Autologous Bone Grafts

Treatment of bone defects caused by trauma or disease is a major burden on human healthcare systems. Although autologous bone grafts are considered as the gold standard, they are limited in availability and are associated with post-operative complications. Minimally invasive alternatives using injectable bone cements are currently used in certain clinical procedures, such as vertebroplasty and balloon kyphoplasty. Nevertheless, given the high incidence of fractures and pathologies that result in bone voids, there is an unmet need for injectable materials with desired properties for minimally invasive procedures. This paper provides an overview of the most common injectable bone cement materials for clinical use. The emphasis has been placed on calcium phosphate cements and acrylic bone cements, while enabling the readers to compare the opportunities and challenges for these two classes of bone cements. This paper also briefly reviews antibiotic-loaded bone cements used in bone repair and implant fixation, including their efficacy and cost for healthcare systems. A summary of the current challenges and recommendations for future directions has been brought in the concluding section of this paper.

Calcium Phosphate Bone Cements Reinforced with Biodegradable Polymer Fibres for Drug Delivery

2014 ◽  
Vol 604 ◽  
pp. 184-187 ◽  
Author(s):  
Zilgma Irbe ◽  
Dagnija Loca ◽  
Ivita Bistrova ◽  
Liga Berzina-Cimdina
Keyword(s):  
Compressive Strength ◽  
Liquid Phase ◽  
Calcium Phosphate ◽  
Tricalcium Phosphate ◽  
Aqueous Fluid ◽  
Dihydrogen Phosphate ◽  
Bone Cements ◽  
Polypropylene Glycol ◽  
Setting Reaction ◽  
Calcium Phosphate Cements

Conventional calcium phosphate bone cements are self setting water based pastes. Recently pre-mixed calcium phosphate bone cements have been proposed that have non-aqueous fluid as liquid phase of the paste. Such cements thus only start setting reaction in contact with body fluids. In this work the properties (cohesion, compressive strength, phase composition) of pre-mixed calcium phosphate cements based on α-tricalcium phosphate and calcium dihydrogen phosphate monohydrate are described. Properties of several cement compositions are examined and compared to properties of β-tricalcium phosphate and calcium dihydrogen phosphate monohydrate based cements. It was found that α-tricalcium phosphate and calcium dihydrogen phosphate monohydrate based cements have higher compressive strength (10 - 15 MPa) than corresponding β-tricalcium phosphate and calcium dihydrogen phosphate monohydrate based cements (10 - 6 MPa). Out of examined cement paste liquids (glycerol, polyethylene glycol and polypropylene glycol) cements using glycerol as the liquid phase had higher compressive strength and are more cohesive.

Calcium Phosphate Bone Cements: A Comprehensive Review

2003 ◽  
Vol 13 (1) ◽  
pp. 8 ◽  
Author(s):  
Denton D. Weiss ◽  
Matthew A. Sachs ◽  
Charles R. Woodard
Keyword(s):  
Calcium Phosphate ◽  
Bone Cements ◽  
Comprehensive Review

scholarly journals Early-stage macroporosity enhancement in calcium phosphate cements by inclusion of poly(N-vinylpyrrolidone) particles as a porogen

2020 ◽  
Vol 23 ◽  
pp. 100901 ◽  
Author(s):  
Irene Lodoso-Torrecilla ◽  
Floris Stumpel ◽  
John A. Jansen ◽  
Jeroen J.J.P. van den Beucken
Keyword(s):  
Calcium Phosphate ◽  
Early Stage ◽  
Calcium Phosphate Cements

Intrinsic porosity of calcium phosphate cements and its significance for drug delivery and tissue engineering applications

2009 ◽  
Vol 5 (7) ◽  
pp. 2752-2762 ◽  
Author(s):  
M. Espanol ◽  
R.A. Perez ◽  
E.B. Montufar ◽  
C. Marichal ◽  
A. Sacco ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Calcium Phosphate ◽  
Engineering Applications ◽  
Calcium Phosphate Cements
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