scholarly journals Synthesis, characterization, and evaluation of PEGylated first-row transition metal ferrite nanoparticles as T2contrast agents for high-field MRI

RSC Advances ◽  
2017 ◽  
Vol 7 (61) ◽  
pp. 38125-38134 ◽  
Author(s):  
Abhinandan Banerjee ◽  
Barbara Blasiak ◽  
Eva Pasquier ◽  
Boguslaw Tomanek ◽  
Simon Trudel

PEGylated MFe2O4(M = Mn through Zn) spinel ferrite preparedviaa novel one-pot synthesis were evaluated for high-field (B0= 9.4 T) magnetic resonance imaging.

2016 ◽  
Vol 55 (21) ◽  
pp. 6187-6191 ◽  
Author(s):  
Joseph M. Keca ◽  
Juan Chen ◽  
Marta Overchuk ◽  
Nidal Muhanna ◽  
Christina M. MacLaughlin ◽  
...  

2016 ◽  
Vol 128 (21) ◽  
pp. 6295-6299 ◽  
Author(s):  
Joseph M. Keca ◽  
Juan Chen ◽  
Marta Overchuk ◽  
Nidal Muhanna ◽  
Christina M. MacLaughlin ◽  
...  

2005 ◽  
Vol 153 (2) ◽  
pp. 239-248 ◽  
Author(s):  
Rudolf Fahlbusch ◽  
Boris v Keller ◽  
Oliver Ganslandt ◽  
Jürgen Kreutzer ◽  
Christopher Nimsky

Objective: The aim of the study was to evaluate the effect of intraoperative high-field (1.5 Tesla) magnetic resonance imaging (MRI) on the results of transsphenoidal surgery of GH-secreting pituitary macroadenomas. Methods: Twenty-three acromegalic patients (mean tumor size, 25 ± 12 mm; untreated preoperative GH, 4.2–159 μg/l; IGF-I, 349–1111 μg/l) were investigated by intraoperative high-field MRI. If intraoperative imaging depicted an accessible tumor remnant, resection was continued. Results: In five patients intraoperative MRI led to further tumor removal, two of these met the consensus criteria for endocrine remission after 3 months. In two patients basal GH and oral glucose tolerance test (OGTT) were <2 μg/l, only IGF-I was slightly elevated, and in one patient GH was <5 μg/l and OGTT was 2 μg/l, with elevated IGF-I. Final intraoperative MRI showed no tumor remnants in 14 patients; eight of them met the consensus criteria for remission of acromegaly. In the patients with MRI showing incomplete removal (four suspect findings and five patients with intended partial removal) none was normalized. Conclusion: With regard to the patients with a tumor configuration in whom complete tumor removal was considered (n = 18), intraoperative MRI increased the rate of endocrine normalization from 33 to 44% applying the consensus criteria, and improved endocrine outcome to ‘nearly normalization’ in another 17%. With regard to preoperative GH levels and tumor size, intraoperative MRI can help to achieve endocrine remission in patients who are normally considered not to be curable. However, taking GH as the tumor marker, even intraoperative high-field MRI was not able to detect tumor remnants in every case.


2013 ◽  
Vol 1 (29) ◽  
pp. 3545 ◽  
Author(s):  
Guohai Liang ◽  
Daixin Ye ◽  
Xianxia Zhang ◽  
Fang Dong ◽  
Hui Chen ◽  
...  

2020 ◽  
Vol 8 (7) ◽  
pp. 1432-1444 ◽  
Author(s):  
Huijing Xiang ◽  
Pingli Dong ◽  
Lei Pi ◽  
Zhijie Wang ◽  
Tingting Zhang ◽  
...  

The synthesis of superparamagnetic nanoclusters is critical for ultra-sensitive magnetic resonance imaging (MRI).


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