scholarly journals Green fluorescent organic nanoparticles based on carbon dots and self-polymerized dopamine for cell imaging

RSC Advances ◽  
2017 ◽  
Vol 7 (46) ◽  
pp. 28987-28993 ◽  
Author(s):  
Tianxiang Zhang ◽  
Hongwei Xu ◽  
He Wang ◽  
Jinyang Zhu ◽  
Yue Zhai ◽  
...  

Fluorescent organic nanoparticles (FON) based on polydopamine (PDA) have recently emerged as a novel fluorescent probe due to its facile synthesis procedure, good water solubility, and excellent biocompatibility.

2021 ◽  
Vol 6 (15) ◽  
pp. 3729-3736
Author(s):  
Xiaoyan Bi ◽  
Xiaoyu Hou ◽  
Xueyun Zhang ◽  
Wen Liu ◽  
Guodong Ren ◽  
...  

2018 ◽  
Vol 15 (1) ◽  
pp. 47-55
Author(s):  
Xuebing Li ◽  
Haifen Yang ◽  
Ning Wang ◽  
Tijian Sun ◽  
Wei Bian ◽  
...  

Background: Morin has many pharmacological functions including antioxidant, anticancer, anti-inflammatory, and antibacterial effects. It is commonly used in the treatment of antiviral infection, gastropathy, coronary heart disease and hepatitis B in clinic. However, researches have shown that morin is likely to show prooxidative effects on the cells when the amount of treatment is at high dose, leading to the decrease of intracellular ATP levels and the increase of necrosis process. Therefore, it is necessary to determine the concentration of morin in biologic samples. Method: Novel water-soluble and green nitrogen and sulfur co-doped carbon dots (NSCDs) were prepared by a microwave heating process with citric acid and L-cysteine. The fluorescence spectra were collected at an excitation wavelength of 350 nm when solutions of NSCDs were mixed with various concentrations of morin. Results: The as-prepared NSCDs were characterized by transmission electron microscopy, X-ray diffraction and X-ray photoelectron spectroscopy. The fluorescence intensity of NSCDs decreased significantly with the increase of morin concentration. The fluorescence intensity of NSCDs displayed a linear response to morin in the concentration 0.10-30 μM with a low detection limit of 56 nM. The proposed fluorescent probe was applied to analysis of morin in human body fluids with recoveries of 98.0-102%. Conclusion: NSCDs were prepared by a microwave heating process. The present analytical method is sensitive to morin. The quenching process between NSCDs and morin is attributed to the static quenching. In addition, the cellular toxicity on HeLa cells indicated that the as-prepared NSCDs fluorescent probe does not show obvious cytotoxicity in cell imaging. Our proposed method possibly opens up a rapid and nontoxic way for preparing heteroatom doped carbon dots with a broad application prospect.


2013 ◽  
Vol 19 (49) ◽  
pp. 16646-16650 ◽  
Author(s):  
Irén Fischer ◽  
Katja Petkau‐Milroy ◽  
Yvonne L. Dorland ◽  
Albertus P. H. J. Schenning ◽  
Luc Brunsveld

2018 ◽  
Vol 1 (5) ◽  
pp. 2324-2331 ◽  
Author(s):  
Dongfeng Dang ◽  
Xiaochi Wang ◽  
Daquan Wang ◽  
Zhiwei Yang ◽  
Dongxiao Hao ◽  
...  

The Analyst ◽  
2020 ◽  
Vol 145 (6) ◽  
pp. 2357-2366 ◽  
Author(s):  
Shanshan Wei ◽  
Lihong Tan ◽  
Xiangyu Yin ◽  
Ruoming Wang ◽  
Xueru Shan ◽  
...  

A sensitive fluorescent probe based on carbon dots has been synthesized by a one-pot hydrothermal method for the rapid detection of intracellular Fe2+.


The Analyst ◽  
2014 ◽  
Vol 139 (7) ◽  
pp. 1692-1696 ◽  
Author(s):  
Weiping Wang ◽  
Ya-Chun Lu ◽  
Hong Huang ◽  
Jiu-Ju Feng ◽  
Jian-Rong Chen ◽  
...  

A simple and green hydrothermal method was developed for preparation of water-soluble nitrogen-doped carbon dots (N-CDs) from streptomycin. The prepared N-CDs reveal low toxicity, high stability and good biocompatibility, which can be used as fluorescent probes for cell imaging.


2016 ◽  
Vol 68 ◽  
pp. 37-42 ◽  
Author(s):  
Chunping Ma ◽  
Xiqi Zhang ◽  
Liutao Yang ◽  
Yujiao Wu ◽  
Hongliang Liu ◽  
...  

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