Synthesis of a biotinylated penta-α-(1→6)-d-glucoside based on the rational design of an α-stereoselective glucosyl donor

2018 ◽  
Vol 5 (6) ◽  
pp. 909-928 ◽  
Author(s):  
Bozhena S. Komarova ◽  
Vera S. Dorokhova ◽  
Yury E. Tsvetkov ◽  
Nikolay E. Nifantiev
Keyword(s):  
Helicobacter Pylori ◽  
Rational Design ◽  
Selective Synthesis ◽  
Protecting Group ◽  
Group Pattern

Rational design of a protecting group pattern in a glucosyl donor allows for the α-selective synthesis of biotinylated pentasaccharides corresponding to the fragment of the α-(1→6)-glucans of Helicobacter pylori.

ChemInform Abstract: Synthesis of Helicobacter pylori Lipid A and Its Analogue Using p-(Trifluoromethyl)benzyl Protecting Group.

ChemInform ◽  
2000 ◽  
Vol 31 (44) ◽  
pp. no-no
Author(s):  
Yasuhiro Sakai ◽  
Masato Oikawa ◽  
Hiroaki Yoshizaki ◽  
Tomohiko Ogawa ◽  
Yasuo Suda ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Lipid A ◽  
Protecting Group

Chemoselective activation of ethyl vs. phenyl thioglycosides: one-pot synthesis of oligosaccharides

2020 ◽  
Vol 18 (44) ◽  
pp. 9029-9034
Author(s):  
Cian Mc Carthy ◽  
Xiangming Zhu
Keyword(s):  
Protecting Group ◽  
One Pot ◽  
One Pot Synthesis ◽  
Group Pattern

Ethyl thioglycosides could be selectively activated in the presence of phenyl thioglycosides carrying the same or even more armed protecting group pattern.

Synthesis of Helicobacter pylori lipid A and its analogue using p-(trifluoromethyl)benzyl protecting group

2000 ◽  
Vol 41 (35) ◽  
pp. 6843-6847 ◽  
Author(s):  
Yasuhiro Sakai ◽  
Masato Oikawa ◽  
Hiroaki Yoshizaki ◽  
Tomohiko Ogawa ◽  
Yasuo Suda ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Lipid A ◽  
Protecting Group

scholarly journals Analysis and prediction of T and B epitopes in Helicobacter pylori proteins: An initial approach to the rational design of alternative therapeutic strategies without the use of antibiotics

2017 ◽  
Vol 33 (3) ◽  
pp. 477-491
Author(s):  
Elkin Navarro-Quiroz ◽  
◽  
Roberto Navarro-Quiroz ◽  
Pierine España-Puccin ◽  
Mostapha Ahmad ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Rational Design ◽  
Therapeutic Strategies ◽  
Initial Approach

The rod-to-coccoid body transformation in cultures of Helicobacter pylori

1990 ◽  
Vol 48 (3) ◽  
pp. 626-627
Author(s):  
A. R. Crooker ◽  
W. G. Kraft ◽  
T. L. Beard ◽  
M. C. Myers
Keyword(s):  
Helicobacter Pylori ◽  
Growth Cycle ◽  
Negative Bacterium ◽  
Body Formation ◽  
Coccoid Form ◽  
Spiral Form ◽  
Prolonged Culture ◽  
H Pylori ◽  
Upper Gastrointestinal

Helicobacter pylori is a microaerophilic, gram-negative bacterium found in the upper gastrointestinal tract of humans. There is strong evidence that H. pylori is important in the etiology of gastritis; the bacterium may also be a major predisposing cause of peptic ulceration. On the gastric mucosa, the organism exists as a spiral form with one to seven sheathed flagella at one (usually) or both poles. Short spirals were seen in the first successful culture of the organism in 1983. In 1984, Marshall and Warren reported a coccoid form in older cultures. Since that time, other workers have observed rod and coccal forms in vitro; coccoid forms predominate in cultures 3-7 days old. We sought to examine the growth cycle of H. pylori in prolonged culture and the mode of coccoid body formation.

Molecular insights on the dynamic stability of peptide nucleic acid functionalized carbon and boron nitride nanotubes

2021 ◽  
Vol 23 (1) ◽  
pp. 219-228
Author(s):  
Nabanita Saikia ◽  
Mohamed Taha ◽  
Ravindra Pandey
Keyword(s):  
Nucleic Acid ◽  
Boron Nitride ◽  
Nucleic Acids ◽  
Dynamic Stability ◽  
Peptide Nucleic Acid ◽  
Rational Design ◽  
Peptide Nucleic Acids ◽  
Boron Nitride Nanotubes ◽  
Molecular Hybrids ◽  
Single Wall Nanotubes

The rational design of self-assembled nanobio-molecular hybrids of peptide nucleic acids with single-wall nanotubes rely on understanding how biomolecules recognize and mediate intermolecular interactions with the nanomaterial's surface.

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