CO2-Stimulated morphology transition of ABC miktoarm star terpolymer assemblies

2017 ◽  
Vol 8 (18) ◽  
pp. 2833-2840 ◽  
Author(s):  
Meng Huo ◽  
Haotian Du ◽  
Min Zeng ◽  
Long Pan ◽  
Tommy Fang ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Self Assembly ◽  
Poly Ethylene Glycol ◽  
Morphology Transition ◽  
Ethyl Methacrylate ◽  
Miktoarm Star ◽  
Poly Ethylene

CO2-Regulated self-assembly of star terpolymers star-[poly(ethylene glycol)-polystyrene-poly[2-(N,N-diethylamino)ethyl methacrylate]] (μ-PEG-PS-PDEA) was studied and an unusual vesicle/microsphere-to-lamella transition upon CO2 stimulation was observed.

Synthesis and Self-Assembly of Well-Defined pH-Responsive Block Glycopolymers

2015 ◽  
Vol 815 ◽  
pp. 359-366 ◽  
Author(s):  
Qing Yun Yu ◽  
Lu Bin Lin ◽  
Xue Yu Xing ◽  
Hai Liang Dong ◽  
Xiao Ze Jiang ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Self Assembly ◽  
Phenylboronic Acid ◽  
Proton Nuclear Magnetic Resonance ◽  
Similar Degree ◽  
Random Structure ◽  
Ph Responsive ◽  
Poly Ethylene Glycol ◽  
Ethyl Methacrylate ◽  
Poly Ethylene

Two pH-responsive block glycopolymers, poly (ethylene glycol)-b-Poly (2- (diethylamino) ethyl methacrylate-co-2-gluconamidoethyl methacrylate) (PEG113-b-P(DEA55-co-GAMA12)) and poly (ethylene glycol)-b-poly (2-(diethylamino) ethyl methacrylate)-b-poly (2-gluconamido ethyl methacrylate) (PEG113-b-PDEA55-b-PGAMA15), were synthesized via atom transfer radical polymerization (ATRP) by directly or successively polymerization of GAMA and DEA monomers using a PEG-based macroinitiator, respectively, without protecting group chemistry. Those block glycopolymers were confirmed by proton Nuclear Magnetic Resonance (1H NMR) and Gel Permeation Chromatography (GPC), and their self-assembly behaviors were characterized by Transmission Electron Microscopy (TEM), Dynamic Light Scattering (DLS) and Zeta-potential. The results show both synthetic block glycopolymers were dissolved molecularly in aqueous solution at acidic pH (such as pH 3), thus it can reversibly convert to be two-layer micelles comprising DEA and GAMA cores, PEG coronas with size of around 50 nm, or micelles comprising DEA cores, GAMA and PEG outer coronas with bigger size of 70 nm for PEG113-b- P(DEA55-co-GAMA12) and PEG113-b-PDEA55-b-PGAMA15), respectively, at basic condition. Both glycopolymers have the micellization process at middle pH (pH 6-8), but possess different isoelectric points (pIs) (at pH 8.0 and 7.8) for their pH responsive block of PEG113-b-P(DEA55-co-GAMA12) and PEG113-b-PDEA55-b-PGAMA15 with DEA-co-GAMA random structure or DEA chain only, respectively. This study not only reveals the self-assembly of pH responsive block glycopolymers with different architectures by fixing similar degree polymerization (DP) of their blocks, but also provides a tool to investigate pH induced dynamic covalent interaction between glycopolymers and phenylboronic acid derivatives or a light for designing novel drug delivery carriers.

Synthesis and thermo-responsive self-assembly behavior of amphiphilic copolymer β-CD–(PCL–P(MEO2MA-co-PEGMA))21 for the controlled intracellular delivery of doxorubicin

RSC Advances ◽  
2016 ◽  
Vol 6 (56) ◽  
pp. 50993-51004 ◽  
Author(s):  
Beibei Lu ◽  
Lei Li ◽  
Lulu Wei ◽  
Xuhong Guo ◽  
Jun Hou ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Self Assembly ◽  
Intracellular Delivery ◽  
Amphiphilic Copolymer ◽  
Poly Ethylene Glycol ◽  
Glycol Methacrylate ◽  
Ethyl Methacrylate ◽  
Assembly Behavior ◽  
Poly Ethylene

Well-defined amphiphilic β-cyclodextrin star-shaped copolymers with poly(ε-caprolactone)–poly(2-(2-methoxyethoxy)ethyl methacrylate)-co-poly(ethylene glycol)methacrylate) (β-CD–(PCL–P(MEO2MA-co-PEGMA))21 were synthesized via (ROP) and (ATRP).

Synthesis and self-assembly behaviour of poly(Nα-Boc-l-tryptophan)-block-poly(ethylene glycol)-block-poly(Nα-Boc-l-tryptophan)

RSC Advances ◽  
2016 ◽  
Vol 6 (29) ◽  
pp. 24142-24153
Author(s):  
Andreea S. Voda ◽  
Kevin Magniez ◽  
Nisa V. Salim ◽  
Cynthia Wong ◽  
Qipeng Guo
Keyword(s):  
Drug Delivery ◽  
Ethylene Glycol ◽  
Self Assembly ◽  
Triblock Copolymers ◽  
Potential Drug ◽  
Poly Ethylene Glycol ◽  
Drug Delivery Applications ◽  
Poly Ethylene ◽  
First Time

We report for the first time the use of Nα-Boc-l-tryptophan for the synthesis of amphiphilic BAB triblock copolymers for potential drug delivery applications.

AB2 Y-shaped miktoarm star conductive polyaniline-modified poly(ethylene glycol) and its electrospun nanofiber blend with poly(ε-caprolactone)

RSC Advances ◽  
2015 ◽  
Vol 5 (46) ◽  
pp. 36715-36726 ◽  
Author(s):  
Bakhshali Massoumi ◽  
Somayeh Davtalab ◽  
Mehdi Jaymand ◽  
Ali Akbar Entezami
Keyword(s):  
Ethylene Glycol ◽  
Electrospun Nanofibers ◽  
Synthesis And Characterization ◽  
Electrospun Nanofiber ◽  
Poly Ethylene Glycol ◽  
Conductive Polyaniline ◽  
Miktoarm Star ◽  
Poly Ethylene ◽  
Type Ab

The aim of this study is the synthesis, and characterization of novel type AB2 Y-shaped miktoarm star conductive polyaniline-modified poly(ethylene glycol), and preparation of its electrospun nanofibers blend with poly(ε-caprolactone).

The Influences of Monomer Structure and Solvent on the Radical Copolymerization of Tertiary Amine and PEGylated Methacrylates

2021 ◽  
Author(s):  
Priscila Quiñonez-Angulo ◽  
Robin Hutchinson ◽  
Angel Licea-Claverie ◽  
Enrique Saldivar ◽  
Ivan Zapata-Gonzalez
Keyword(s):  
Ethylene Glycol ◽  
Methyl Ether ◽  
Tertiary Amine ◽  
Radical Copolymerization ◽  
Poly Ethylene Glycol ◽  
Ethyl Methacrylate ◽  
Monomer Structure ◽  
Poly Ethylene ◽  
Glycol Methyl Ether

Tertiary Amine Methacrylates (TAMAs), such as 2-(N,N-diethylamino)ethyl methacrylate (DEAEMA) and 2-(N,N-dimethylamino)ethyl methacrylate (DMAEMA), and PEGylated (macro)monomers, such as 2-ethoxyethyl methacrylate (EEMA1) and poly(ethylene glycol) methyl ether methacrylates with 9 and...

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