Asymmetric Michael addition in an aqueous environment with the assistance of optically active hyperbranched polymers

2017 ◽  
Vol 8 (11) ◽  
pp. 1771-1777 ◽  
Author(s):  
Hongli Zhang ◽  
Qijin Zhang ◽  
Chunyan Hong ◽  
Gang Zou
Keyword(s):  
Michael Addition ◽  
Hyperbranched Polymer ◽  
Addition Reaction ◽  
Product Yield ◽  
Hyperbranched Polymers ◽  
Optically Active ◽  
Aqueous Environment ◽  
Michael Addition Reaction ◽  
Asymmetric Michael Addition ◽  
High Product Yield

A novel optically active hyperbranched polymer can serve as the chiral scaffolds to promote asymmetric Michael addition reaction in an aqueous environment with a high product yield and enantioselectivity.

The design of a spiro-pyrrolidine organocatalyst and its application to catalytic asymmetric Michael addition for the construction of all-carbon quaternary centers

2015 ◽  
Vol 51 (49) ◽  
pp. 9979-9982 ◽  
Author(s):  
Jin-Miao Tian ◽  
Yong-Hai Yuan ◽  
Yong-Qiang Tu ◽  
Fu-Min Zhang ◽  
Xiao-Bo Zhang ◽  
...  
Keyword(s):  
Michael Addition ◽  
Addition Reaction ◽  
Silyl Ether ◽  
Michael Addition Reaction ◽  
Quaternary Centers ◽  
Asymmetric Michael Addition ◽  
Catalytic Asymmetric

A novel chiral spiro-pyrrolidine silyl ether organocatalyst has been designed and applied to an asymmetric Michael addition reaction.

Asymmetric Michael addition of ketones to nitroolefins: pyrrolidinyl-oxazole-carboxamides as new efficient organocatalysts

2014 ◽  
Vol 12 (40) ◽  
pp. 8008-8018 ◽  
Author(s):  
Ahmed Kamal ◽  
Manda Sathish ◽  
Vunnam Srinivasulu ◽  
Jadala Chetna ◽  
Kunta Chandra Shekar ◽  
...  
Keyword(s):  
Michael Addition ◽  
Addition Reaction ◽  
Mechanistic Studies ◽  
Michael Addition Reaction ◽  
Asymmetric Michael Addition

New pyrrolidinyl-oxazole-carboxamides were synthesized and utilized as efficient organocatalysts for asymmetric Michael addition reaction. In addition, computational mechanistic studies were performed.

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