An approach towards the synthesis of novel fused nitrogen tricyclic heterocyclic scaffolds via GBB reaction

2018 ◽  
Vol 16 (8) ◽  
pp. 1287-1296 ◽  
Author(s):  
Sandip Gangadhar Balwe ◽  
Yeon Tae Jeong

A concise and efficient one-pot synthesis of novel N-fused tricyclic derivatives has been developed by using the Groebke–Blackburn–Bienaymé (GBB) reaction, which involved the reaction of 3-amino-1H-indazoles, aldehydes and isonitriles to afford 2-aryl-5H-imidazo[1,2-b]indazol-3-amine derivatives via a formal [4 + 1] cycloaddition reaction.

2017 ◽  
Vol 19 (20) ◽  
pp. 4858-4864 ◽  
Author(s):  
F. A. Kucherov ◽  
K. I. Galkin ◽  
E. G. Gordeev ◽  
V. P. Ananikov

Efficient one-pot synthesis of tricyclic compounds from biobased 5-hydroxymethylfurfural (HMF) is described using a [4 + 2] cycloaddition reaction.


2014 ◽  
Vol 79 (16) ◽  
pp. 7772-7777 ◽  
Author(s):  
Simon Specklin ◽  
Elodie Decuypere ◽  
Lucie Plougastel ◽  
Soifia Aliani ◽  
Frédéric Taran

ChemInform ◽  
2015 ◽  
Vol 46 (7) ◽  
pp. no-no
Author(s):  
Simon Specklin ◽  
Elodie Decuypere ◽  
Lucie Plougastel ◽  
Soifia Aliani ◽  
Frederic Taran

Heterocycles ◽  
1994 ◽  
Vol 38 (3) ◽  
pp. 587 ◽  
Author(s):  
Yoshimitsu Nagao ◽  
Kweon Kim ◽  
Yoichi Komaki ◽  
Shigeki Sano ◽  
Masaru Kihara ◽  
...  

Synlett ◽  
2019 ◽  
Vol 31 (01) ◽  
pp. 73-76 ◽  
Author(s):  
Yan-Mei Yan ◽  
Hao-Yang Li ◽  
Min Zhang ◽  
Rong-Xin Wang ◽  
Chen-Guang Zhou ◽  
...  

A convenient and one-pot approach to prepare [1,2,3]triazolo[1,5-a]quinoxalin-4(5H)-ones by a metal-free sequential Ugi-4CR/alkyne–azide cycloaddition reaction has been developed. The reaction of 2-azidobenzenamines, aldehydes, propiolic acids, and isocyanides produced the Ugi adducts, which were transformed to the [1,2,3]triazolo[1,5-a]quinoxalin-4(5H)-ones in moderate to good yields via alkyne–azide cycloaddition reaction.


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