I2 catalyzed access of spiro[indoline-3,4′-pyridine] appended amine dyad: new ON–OFF chemosensors for Cu2+ and imaging in living cells

2018 ◽  
Vol 16 (2) ◽  
pp. 302-315 ◽  
Author(s):  
Animesh Mondal ◽  
Barnali Naskar ◽  
Sanchita Goswami ◽  
Chandraday Prodhan ◽  
Keya Chaudhuri ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Hepg2 Cells ◽  
Cell Imaging ◽  
Colorimetric Detection ◽  
Living Cells ◽  
Fluorescent Cell

An efficient, easily tuneable route to construct a structurally diverse organic fluorescent probe and its applications towards the colorimetric detection of Cu2+ ions and in vitro fluorescent cell imaging of Cu2+ in HepG2 cells.

The development of a hemicyanine-based ratiometric CO fluorescent probe with a long emission wavelength and its applications for imaging CO in vitro and in vivo

2020 ◽  
Vol 44 (28) ◽  
pp. 12107-12112 ◽  
Author(s):  
Yunyan Zhang ◽  
Xiuqi Kong ◽  
Yonghe Tang ◽  
Min Li ◽  
Yaguang Yin ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Living Cells ◽  
Emission Wavelength ◽  
Long Wavelength ◽  
Wavelength Emission ◽  
Ratiometric Fluorescent Probe

A novel ratiometric fluorescent probe, Hcy-CO, with long-wavelength emission was developed for visualizing CO in living cells and zebrafish.

scholarly journals A highly selective fluorescent probe for the sensing of Cu2+ based on the hydrolysis of a quinoline-2-carboxylate and its application in cell imaging

2020 ◽  
pp. 174751982097392
Author(s):  
Qihua You ◽  
Yihua Zhuo ◽  
Yadong Feng ◽  
Yujuan Xiao ◽  
Yanyu Zhang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Cell Imaging ◽  
High Selectivity ◽  
Living Cells ◽  
World Health ◽  
Strong Fluorescence ◽  
The World ◽  
Phenolic Group ◽  
Health Organization ◽  
Hydrolysis Of

A highly selective OFF–ON fluorescent probe is developed for the sensing of Cu2+ based on the hydrolysis of a quinoline-2-carboxylate moiety. The probe is weakly fluorescent due to esterification of the phenolic group. Upon treatment with 1 equiv. of Cu2+, the probe exhibits strong fluorescence at 570 nm. The probe also exhibits high selectivity for Cu2+ over other cations with a low detection limit of 0.2 μM, which is sensitive enough to meet the standard of the World Health Organization for Cu2+ in drinking water (30 μM). Moreover, the probe shows a very low cell cytotoxicity, and imaging experiments demonstrate that the probe can be used for the sensing of Cu2+ in living cells.

scholarly journals A naphthalimide-based turn-on fluorescence probe for peroxynitrite detection and imaging in living cells

RSC Advances ◽  
2020 ◽  
Vol 10 (63) ◽  
pp. 38281-38286
Author(s):  
Xiling Liu ◽  
Fangyuan Gu ◽  
Xinyi Zhou ◽  
Wei Zhou ◽  
Shuping Zhang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Hepg2 Cells ◽  
Fluorescence Probe ◽  
Living Cells ◽  
Selective Detection ◽  
C Elegans ◽  
Turn On

A novel fluorescent probe HCA-OH was designed for selective detection of peroxynitrite and imaging in HepG2 cells and C. elegans.

A novel near-infrared xanthene-based fluorescent probe for detection of thiophenol in vitro and in vivo

2020 ◽  
Vol 44 (40) ◽  
pp. 17360-17367
Author(s):  
Yongquan Wu ◽  
Aiping Shi ◽  
Huiying Liu ◽  
Yuanyan Li ◽  
Weican Lun ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Near Infrared ◽  
Living Cells

A novel near-infrared xanthene-based fluorescent probe for detection of thiophenol in living cells and mice.

A multi-functional guanine derivative for studying the DNA G-quadruplex structure

The Analyst ◽  
2017 ◽  
Vol 142 (21) ◽  
pp. 4083-4088 ◽  
Author(s):  
Takumi Ishizuka ◽  
Pei-Yan Zhao ◽  
Hong-Liang Bao ◽  
Yan Xu
Keyword(s):  
Fluorescent Probe ◽  
Living Cells ◽  
Quadruplex Structure ◽  
G Quadruplex ◽  
Quadruplex Formation

A multi-functional guanine derivative, 8FG, as a G-quadruplex stabilizer, a fluorescent probe for the detection of G-quadruplex formation, and a 19F sensor for the observation of the G-quadruplex in vitro and in living cells.

A resorufin-based fluorescent probe for imaging polysulfides in living cells

The Analyst ◽  
2019 ◽  
Vol 144 (10) ◽  
pp. 3221-3225 ◽  
Author(s):  
Jingwei Liu ◽  
Zheng Yin
Keyword(s):  
Fluorescent Probe ◽  
Biomedical Research ◽  
Living Cells ◽  
Turn On

Nowadays H2Sn have attracted ever-increasing attention in the field of biomedical research. Herein, we report a resorufin-based “turn-on” probe for H2Sn sensing in vitro and in living cells.

A tumor-specific and mitochondria-targeted fluorescent probe for real-time sensing of hypochlorite in living cells

2017 ◽  
Vol 53 (40) ◽  
pp. 5539-5541 ◽  
Author(s):  
Kun Li ◽  
Ji-Ting Hou ◽  
Jin Yang ◽  
Xiao-Qi Yu
Keyword(s):  
Cancer Cells ◽  
Real Time ◽  
Fluorescent Probe ◽  
Cell Imaging ◽  
Living Cells

The first dual-targeted (both cancer cells and mitochondria) fluorescent probe for sensing mitochondrial hypochlorite was presented and applied in cell imaging.

A highly selective and sensitive fluorescent probe for Cu2+based on a novel naphthalimide–rhodamine platform and its application in live cell imaging

2017 ◽  
Vol 15 (18) ◽  
pp. 3947-3954 ◽  
Author(s):  
Chang Liu ◽  
Xiaojie Jiao ◽  
Song He ◽  
Liancheng Zhao ◽  
Xianshun Zeng
Keyword(s):  
Fluorescent Probe ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
Living Cells ◽  
Live Cell ◽  
Ratiometric Fluorescent Probe

A bifluorophore-based ratiometric fluorescent probe has been developed. The probe is cell-permeable and can be used as a FRET-based ratiometric fluorescent probe for lysosomal Cu2+imaging in living cells.

Dynamic Imaging of Moving Cells Based on DNA Nanotechnology

2020 ◽  
Vol 12 (2) ◽  
pp. 211-220
Author(s):  
Xin Zhong
Keyword(s):  
Fluorescent Probe ◽  
Self Assembly ◽  
Fluorescence Probe ◽  
Structural Characteristics ◽  
Physiological State ◽  
Dna Nanotechnology ◽  
Living Cells ◽  
Fluorescent Labeling ◽  
Dynamic Imaging

Nanostructures based on DNA self-assembly have made great progress in recent years, and have been widely used. Therefore, the research method of dynamic imaging of moving cells based on DNA nanotechnology is proposed. The dynamic imaging process of moving cells is studied from two kinds of DNA Nanotechnologies: DNA gene locus marker and DNA nano-fluorescence probe. Among them, crispr-cas9 system is used to mark DNA gene sites through in vitro fluorescent labeling of different sgRNAs, which can mark different gene sites in cells in multi-color and track gene sites in living cells dynamically; based on self-assembled CdTe quantum dot @ AnnexinV-DNA nanowire fluorescent probe, based on the DNA fitness of moving cells, the system is designed to be specific to target moving cells. The specific detection of motor cells can be realized by combining the sequences. The key point is to use the structural characteristics of the probe to realize the indication of the physiological changes of the drug receiving cells. The results show that: the polychromatic labeling of different gene sites in the same cell can be realized by using different fluorescent labeled sgRNA. By using fluorescent labeled telomere specific sgRNA to track the movement of telomeres in living cells, it can be seen from the movement track that in living cells, Ma SAT is more flexible than that in living cells. About 84.5% of Ma SAT is not mobile, but only 12.9% for telomere. Ma sat and the direction of telomere movement in the cell nucleus are random and in all directions. CdTe QD @ AnnexinV-DNA nanowire fluorescent probe can not only detect the moving cells, but also indicate the physiological state of normal and apoptotic cells at the same time. A large number of S7 ends of DNA allow the probe to firmly bind to the surface of Ramos cells in the way of "twine ball." The probe can indicate the physiological state of cells, and the corresponding characteristic emission wavelength changes with the change of target cell movement state. It shows that DNA nanotechnology can be used to analyze the dynamic imaging of moving cells in all directions and from multiple angles.

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