scholarly journals 8-Oxo-7,8-dihydro-2′-deoxyguanosine and abasic site tandem lesions are oxidation prone yielding hydantoin products that strongly destabilize duplex DNA

2017 ◽  
Vol 15 (39) ◽  
pp. 8341-8353 ◽  
Author(s):  
Aaron M. Fleming ◽  
Cynthia J. Burrows
Keyword(s):  
Duplex Dna ◽  
Abasic Site ◽  
Tandem Lesions

8-Oxo-2′-deoxyguanosine in a tandem lesion context is two orders of magnitude more susceptible to oxidation than in a context of native DNA yielding hydantoin products.

Solution Structure of a Duplex DNA with an Abasic Site in a dA Tract†

Biochemistry ◽  
1997 ◽  
Vol 36 (39) ◽  
pp. 11629-11639 ◽  
Author(s):  
Ke Yu Wang ◽  
Sharon A. Parker ◽  
Igor Goljer ◽  
Philip H. Bolton
Keyword(s):  
Solution Structure ◽  
Duplex Dna ◽  
Abasic Site

Effects of the presence of an aldehydic abasic site on the thermal stability and rates of helix opening and closing of duplex DNA

Biochemistry ◽  
1992 ◽  
Vol 31 (46) ◽  
pp. 11614-11619 ◽  
Author(s):  
Igor Goljer ◽  
Jane M. Withka ◽  
Jung Yie Kao ◽  
Philip H. Bolton
Keyword(s):  
Thermal Stability ◽  
Duplex Dna ◽  
Abasic Site ◽  
Opening And Closing

scholarly journals Participation of glutamic acid 23 of T4 endonuclease V in theβ-elimination reaction of an abasic site in a synthetic duplex DNA

1992 ◽  
Vol 20 (18) ◽  
pp. 4761-4764 ◽  
Author(s):  
Naoko Hori ◽  
Tomoko Doi ◽  
Yoko Karaki ◽  
Masakazu Kituchi ◽  
Morio Ikehara ◽  
...  
Keyword(s):  
Glutamic Acid ◽  
Duplex Dna ◽  
Elimination Reaction ◽  
Abasic Site ◽  
Endonuclease V

scholarly journals On the Formation and Properties of Interstrand DNA–DNA Cross-Links Forged by Reaction of an Abasic Site with the Opposing Guanine Residue of 5′-CAp Sequences in Duplex DNA

2013 ◽  
Vol 135 (3) ◽  
pp. 1015-1025 ◽  
Author(s):  
Kevin M. Johnson ◽  
Nathan E. Price ◽  
Jin Wang ◽  
Mostafa I. Fekry ◽  
Sanjay Dutta ◽  
...  
Keyword(s):  
Duplex Dna ◽  
Abasic Site ◽  
Guanine Residue ◽  
Cross Links

2-Aminopurine-Modified Abasic-Site-Containing Duplex DNA for Highly Selective Detection of Theophylline

2009 ◽  
Vol 131 (7) ◽  
pp. 2448-2449 ◽  
Author(s):  
Minjie Li ◽  
Yusuke Sato ◽  
Seiichi Nishizawa ◽  
Takehiro Seino ◽  
Kodai Nakamura ◽  
...  
Keyword(s):  
Selective Detection ◽  
Duplex Dna ◽  
Abasic Site

scholarly journals Interstrand Cross-Link Formation Involving Reaction of a Mispaired Cytosine Residue with an Abasic Site in Duplex DNA

2021 ◽  
Author(s):  
Jacqueline Gamboa Varela ◽  
Luke E. Pierce ◽  
Xu Guo ◽  
Nathan E. Price ◽  
Kevin M. Johnson ◽  
...  
Keyword(s):  
Duplex Dna ◽  
Abasic Site ◽  
Cross Link ◽  
Cytosine Residue ◽  
Link Formation

Target-controlled formation of silver nanoclusters in abasic site-incorporated duplex DNA for label-free fluorescence detection of theophylline

Nanoscale ◽  
2014 ◽  
Vol 6 (17) ◽  
pp. 9977-9982 ◽  
Author(s):  
Ki Soo Park ◽  
Seung Soo Oh ◽  
H. Tom Soh ◽  
Hyun Gyu Park
Keyword(s):  
Fluorescence Detection ◽  
Silver Nanoclusters ◽  
Sensitive Detection ◽  
Duplex Dna ◽  
Label Free ◽  
Abasic Site

A novel, label-free, fluorescence based sensor for the selective and sensitive detection of theophylline has been developed.

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