Copper-catalyzed oxidative decarboxylative coupling of α-keto acids and sulfoximines

2017 ◽  
Vol 15 (20) ◽  
pp. 4320-4327 ◽  
Author(s):  
Chaleena Pimpasri ◽  
Ladawan Sumunnee ◽  
Sirilata Yotphan
Keyword(s):  
Keto Acids ◽  
Decarboxylative Coupling

The formation of N-aroylsulfoximines via a copper-catalyzed oxidative decarboxylative coupling of α-keto acids with NH-sulfoximines is reported.

scholarly journals Ultrasound-enhanced Ag-catalyzed decarboxylative coupling between α-keto acids and disulfides for the synthesis of thioesters

2018 ◽  
Vol 49 ◽  
pp. 41-46 ◽  
Author(s):  
Laura Abenante ◽  
Filipe Penteado ◽  
Marcelo M. Vieira ◽  
Gelson Perin ◽  
Diego Alves ◽  
...  
Keyword(s):  
Keto Acids ◽  
Decarboxylative Coupling

ChemInform Abstract: Catalyst-Free Direct Decarboxylative Coupling of α-Keto Acids with Thiols: A Facile Access to Thioesters.

ChemInform ◽  
2015 ◽  
Vol 46 (44) ◽  
pp. no-no
Author(s):  
Kelu Yan ◽  
Daoshan Yang ◽  
Wei Wei ◽  
Jing Zhao ◽  
Yuanyuan Shuai ◽  
...  
Keyword(s):  
Catalyst Free ◽  
Keto Acids ◽  
Decarboxylative Coupling

Metal-free electrochemical synthesis of α-ketoamides via decarboxylative coupling of α-keto acids with isocyanides and water

2021 ◽  
Author(s):  
Feng Zhao ◽  
Na Meng ◽  
Ting Sun ◽  
Jiangwei Wen ◽  
Xiaohui Zhao ◽  
...  
Keyword(s):  
Electrochemical Synthesis ◽  
Coupling Reaction ◽  
Environmentally Benign ◽  
Metal Free ◽  
Keto Acids ◽  
Decarboxylative Coupling

A mild and environmentally benign electrochemical strategy has been developed for the synthesis of α-ketoamides via a decarboxylative coupling reaction of α-keto acids with isocyanides and water. The present reaction...

Catalyst-free direct decarboxylative coupling of α-keto acids with thiols: a facile access to thioesters

2015 ◽  
Vol 13 (26) ◽  
pp. 7323-7330 ◽  
Author(s):  
Kelu Yan ◽  
Daoshan Yang ◽  
Wei Wei ◽  
Jing Zhao ◽  
Yuanyuan Shuai ◽  
...  
Keyword(s):  
Catalyst Free ◽  
Keto Acids ◽  
Decarboxylative Coupling

A catalyst-free protocol has been demonstrated for the synthesis of thioesters via the direct decarboxylation of α-keto acids with thiols.

Ketones from Nickel-Catalyzed Decarboxylative, Non-Symmetric Cross-Electrophile Coupling of Carboxylic Acid Esters

2019 ◽  
Author(s):  
Jiang Wang ◽  
Brian P. Cary ◽  
Peyton Beyer ◽  
Samuel H. Gellman ◽  
Daniel Weix
Keyword(s):  
Carboxylic Acid ◽  
Solid Support ◽  
Reaction Conditions ◽  
Decarboxylative Coupling ◽  
New Strategy ◽  
The Cross ◽  
Acyl Donors ◽  
Acid Esters

A new strategy for the synthesis of ketones is presented based upon the decarboxylative coupling of N-hydroxyphthalimide (NHP) esters with S-2-pyridyl thioesters. The reactions are selective for the cross-coupled product because NHP esters act as radical donors and the thioesters act as acyl donors. The reaction conditions are general and mild, with over 40 examples presented, including larger fragments and the 20-mer peptide Exendin(9-39) on solid support.

Connecting Remote C–H Bond Functionalization and Decarboxylative Coupling Using Simple Amines

2019 ◽  
Author(s):  
Francisco de Azambuja ◽  
Ming-Hsiu Yang ◽  
Alexander Bruecker ◽  
Paul Cheong ◽  
Ryan Altman
Keyword(s):  
Organic Molecules ◽  
Mechanistic Studies ◽  
Bond Functionalization ◽  
Bond Forming ◽  
Decarboxylative Coupling

The manuscript describes a Pd-catalyzed reaction of benzylic electrophiles that gives para-substituted arene products. Mechanistic studies suggest a mechanism involving a dearomative C–C bond-forming step, followed by base-mediated rearomatization. This mechanism is uncommon and underappreciated in Pd-catalysis and further exploitation of this mechanism should enable access to other organic molecules.

pH Dependence of the polarographic limiting currents of α-keto acids

1961 ◽  
Vol 26 (1) ◽  
pp. 141-155 ◽  
Author(s):  
S. Ono ◽  
M. Takagi ◽  
T. Wasa
Keyword(s):  
Ph Dependence ◽  
Keto Acids
Sign in / Sign up

Export Citation Format

Share Document