Palladium(0)-catalyzed [2 + 2 + 1] cyclization of 1,6-enynes with vinyl bromides: a highly diastereoselective synthesis of tetrahydro-1H-cyclopenta[c]furans bearing two quaternary carbon centers

2017 ◽  
Vol 15 (21) ◽  
pp. 4601-4608 ◽  
Author(s):  
Yunxia Diao ◽  
Zhijun Zuo ◽  
Hui Wang ◽  
Jingjing Liu ◽  
Xinjun Luan
Keyword(s):  
Efficient Method ◽  
Diastereoselective Synthesis ◽  
Quaternary Carbon ◽  
Carbon Centers ◽  
Highly Efficient

A highly efficient method for the diastereoselective synthesis of cyclopenta[c]furans was developed by Pd(0)-catalyzed [2 + 2 + 1] cyclization of 1,6-enynes with vinyl bromides.

ChemInform Abstract: Diastereoselective Synthesis of Ring-Fused Thiocarbamates Bearing Contiguous Quaternary Carbon Centers.

ChemInform ◽  
2013 ◽  
Vol 44 (42) ◽  
pp. no-no
Author(s):  
Qi-Xiang Guo ◽  
Li-Jun Zhang ◽  
Liu Song ◽  
Biao Xu ◽  
Dong-Rong Xiao ◽  
...  
Keyword(s):  
Diastereoselective Synthesis ◽  
Quaternary Carbon ◽  
Carbon Centers

scholarly journals Highly Efficient and Diastereoselective Construction of Substituted Pyrrolidines Bearing A Quaternary Carbon Center via 1,3-Dipolar [3 + 2] Cycloaddition

2021 ◽  
Author(s):  
Kaikai wang ◽  
Yanli Li ◽  
Yingchao Zhao ◽  
Aili sun ◽  
Rongxiang Chen ◽  
...  
Keyword(s):  
Efficient Method ◽  
Azomethine Ylides ◽  
Dipolar Cycloaddition ◽  
Quaternary Carbon ◽  
Reaction Conditions ◽  
Highly Efficient ◽  
High Yields

A general approach to substituted pyrrolidines via [3 + 2] 1,3-dipolar cycloaddition between nonstabilized azomethine ylides and cyanosulfones was developed. The efficient method provides a series of substituted pyrrolidines bearing a quaternary carbon center in high yields (up to 98%) excellent diastereoselectivities (up to >25:1 dr) under ambient reaction conditions.

Diastereoselective synthesis of ring-fused thiocarbamates bearing contiguous quaternary carbon centers

2013 ◽  
Vol 54 (27) ◽  
pp. 3565-3567 ◽  
Author(s):  
Qi-Xiang Guo ◽  
Li-Jun Zhang ◽  
Liu Song ◽  
Biao Xu ◽  
Dong-Rong Xiao ◽  
...  
Keyword(s):  
Diastereoselective Synthesis ◽  
Quaternary Carbon ◽  
Carbon Centers
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