Triamide macrocyclic chloride receptors via a one-pot tandem reduction–condensation–cyclization reaction

2017 ◽  
Vol 15 (23) ◽  
pp. 4937-4940 ◽  
Author(s):  
Harekrushna Behera ◽  
Venkatachalam Ramkumar ◽  
Nandita Madhavan

A chloride binding triamide macrocycle has been developed in one pot from the corresponding monomer via tandem reduction–condensation–cyclization reactions.

2018 ◽  
Vol 16 (21) ◽  
pp. 4013-4020 ◽  
Author(s):  
Akinari Sumita ◽  
Jinhee Lee ◽  
Yuko Otani ◽  
Tomohiko Ohwada

We present a one-pot two-step methodology, in which an unprotected amino is tolerated, for rapidly synthesizing 2,3-benzodiazepines via phosphate-assisted acylation reaction and hydrazine cyclization reaction.


2017 ◽  
Vol 19 (19) ◽  
pp. 5118-5121 ◽  
Author(s):  
Sara I. Purificação ◽  
Marina J. D. Pires ◽  
Rafael Rippel ◽  
A. Sofia Santos ◽  
M. Manuel B. Marques

2009 ◽  
Vol 351 (1-2) ◽  
pp. 141-146 ◽  
Author(s):  
Yun Shi ◽  
Jing Huang ◽  
Yan-Fang Yang ◽  
Lu-Yong Wu ◽  
Yan-Ning Niu ◽  
...  

2015 ◽  
Vol 51 (53) ◽  
pp. 10612-10615 ◽  
Author(s):  
Min Tang ◽  
Dong Xing ◽  
Haoxi Huang ◽  
Wenhao Hu

A highly efficient sequencing of enantioselective three-component reactions with a variety of one-pot subsequent cyclization reactions was developed.


ChemInform ◽  
2013 ◽  
Vol 44 (38) ◽  
pp. no-no
Author(s):  
Geert Hooyberghs ◽  
Hendrik De Coster ◽  
Dipak D. Vachhani ◽  
Denis S. Ermolat'ev ◽  
Erik V. Van der Eycken
Keyword(s):  

2016 ◽  
Vol 3 (11) ◽  
pp. 1416-1419 ◽  
Author(s):  
Wei Zhou ◽  
Zhenting Yue ◽  
Junliang Zhang

A highly efficient one-pot trifluoromethylation/cyclization reaction of conjugated enyne aldehydes and ketones was developed, which provides modular access to highly substituted trifluoromethylated furans and 2,3-dihydrofurans.


2016 ◽  
Vol 14 (43) ◽  
pp. 10175-10179 ◽  
Author(s):  
Satavisha Kayal ◽  
Santanu Mukherjee

Cascade Michael/cyclization reactions between 3-isothiocyanato oxindoles and exocyclic α,β-unsaturated ketones are shown to proceed in the presence of a tertiary amino-squaramide catalyst and furnish 3,2′-pyrrolidinyl bispirooxindoles with excellent enantioselectivities (up to 99 : 1 er).


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