Se@SiO2–FA–CuS nanocomposites for targeted delivery of DOX and nano selenium in synergistic combination of chemo-photothermal therapy

Nanoscale ◽  
2018 ◽  
Vol 10 (6) ◽  
pp. 2866-2875 ◽  
Author(s):  
Yeying Wang ◽  
Xijian Liu ◽  
Guoying Deng ◽  
Jian Sun ◽  
Haikuan Yuan ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Treatment ◽  
Targeted Delivery ◽  
Photothermal Therapy ◽  
Stimuli Responsive ◽  
Delivery Vehicle ◽  
Drug Delivery Vehicle ◽  
Synergistic Combination

A tumor-targeted and multi-stimuli-responsive drug delivery vehicle (Se@SiO2–FA–CuS/DOX) was fabricated for combined PTT with chemotherapy of DOX and Se in cancer treatment.

Stimuli-responsive biodegradable polyurethane nano-constructs as a potential triggered drug delivery vehicle for cancer therapy

2020 ◽  
Vol 588 ◽  
pp. 119781
Author(s):  
Kavita R. Gajbhiye ◽  
Bhushan P. Chaudhari ◽  
Varsha B. Pokharkar ◽  
Atmaram Pawar ◽  
Virendra Gajbhiye
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Stimuli Responsive ◽  
Delivery Vehicle ◽  
Drug Delivery Vehicle ◽  
Biodegradable Polyurethane

Dendrimer-magnetic nanoparticles as multiple stimuli responsive and enzymatic drug delivery vehicle

2015 ◽  
Vol 380 ◽  
pp. 7-12 ◽  
Author(s):  
Sudeshna Chandra ◽  
Glen Noronha ◽  
Sascha Dietrich ◽  
Heinrich Lang ◽  
Dhirendra Bahadur
Keyword(s):  
Drug Delivery ◽  
Magnetic Nanoparticles ◽  
Stimuli Responsive ◽  
Delivery Vehicle ◽  
Drug Delivery Vehicle

scholarly journals An l-proline based thermoresponsive and pH-switchable nanogel as a drug delivery vehicle

2018 ◽  
Vol 9 (17) ◽  
pp. 2271-2280 ◽  
Author(s):  
Y. Salinas ◽  
A. M. Castilla ◽  
M. Resmini
Keyword(s):  
Drug Delivery ◽  
Stimuli Responsive ◽  
Delivery Vehicle ◽  
Drug Delivery Vehicle

The synthesis and characterisation of a novel dual stimuli-responsive nanogel, based on thermoresponsive N-n-propylacrylamide and an l-proline based monomer acting as a pH-switcher, is reported here.

scholarly journals Pectin Matrix as Oral Drug Delivery Vehicle for Colon Cancer Treatment

2010 ◽  
Vol 12 (1) ◽  
pp. 201-214 ◽  
Author(s):  
Tin Wui Wong ◽  
Gaia Colombo ◽  
Fabio Sonvico
Keyword(s):  
Drug Delivery ◽  
Colon Cancer ◽  
Cancer Treatment ◽  
Oral Drug Delivery ◽  
Oral Drug ◽  
Delivery Vehicle ◽  
Drug Delivery Vehicle

The Smart Dual-Stimuli Responsive Nanoparticles for Controlled AntiTumor Drug Release and Cancer Therapy

2020 ◽  
Vol 20 ◽  
Author(s):  
Feng Wu ◽  
Fei Qiu ◽  
Siew Anthony Wai-Keong ◽  
Yong Diao
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Release ◽  
Targeted Delivery ◽  
Relevant Information ◽  
Therapeutic Effects ◽  
Stimuli Responsive ◽  
Control Effect ◽  
Chemotherapy Drugs ◽  
Excellent Control

Background: In recent years, the emergence of stimuli-responsive nanoparticles makes drug delivery more efficient. As an intelligent and effective targeted delivery platform, it can reduce the side effects generated during drug transportation while enhancing the treatment efficacy. The stimuli-responsive nanoparticles can respond to different stimuli at corresponding times and locations to deliver and release their drugs and associated therapeutic effects. Objective: This review aims to inform researchers on the latest advances in the application of dual-stimuli responsive nanoparticles in precise drug delivery, with special attention to their design, drug release properties, and therapeutic effects. Syntheses of nanoparticles with simultaneous or sequential responses to two or more stimuli (pH-redox, pH-light, redoxlight, temperature-magnetic, pH-redox-temperature, redox-enzyme-light, etc.) and the applications of such responsivity properties for drugs control and release have become a hot topic of recent research. Methods: A database of relevant information for the production of this review was sourced, screened and analyzed from Pubmed, Web of Science, SciFinder by searching for the following keywords: “dual-stimuli responsive”, “controlled release”, “cancer therapy”, “synergistic treatment”. Results: Notably, the nanoparticles with dual-stimuli responsive function have an excellent control effect on drug delivery and release, playing a crucial part in the treatment of tumors. They can improve the encapsulation and delivery efficiency of hydrophobic chemotherapy drugs, combine chemo-photothermal therapies, apply imaging function in the diagnosis of tumors and even conduct multi-drugs delivery to overcome multi-drugs resistance (MDR). Conclusion: With the development of smart dual-stimuli responsive nanoparticles, cancer treatment methods will become more diverse and effective. All the stimuli-responsive nanoparticles functionalities exhibited their characteristics individually within the single nanosystem.

Sign in / Sign up

Export Citation Format

Share Document