Near-infrared optical and X-ray computed tomography dual-modal imaging probe based on novel lanthanide-doped K0.3Bi0.7F2.4 upconversion nanoparticles

Nanoscale ◽  
2018 ◽  
Vol 10 (3) ◽  
pp. 1394-1402 ◽  
Author(s):  
Ran An ◽  
Pengpeng Lei ◽  
Peng Zhang ◽  
Xia Xu ◽  
Jing Feng ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Near Infrared ◽  
Upconversion Nanoparticles ◽  
X Ray ◽  
Imaging Probe ◽  
X Ray Computed

Novel citrate-coated K0.3Bi0.7F2.4:20% Yb3+/0.5% Tm3+ could be employed as a bioprobe for NIR optical and CT dual-modal imaging.

scholarly journals Encapsulation of Upconversion Nanoparticles in Periodic Mesoporous Organosilicas

Molecules ◽  
2019 ◽  
Vol 24 (22) ◽  
pp. 4054 ◽  
Author(s):  
Saher Rahmani ◽  
Chiara Mauriello Jimenez ◽  
Dina Aggad ◽  
Daniel González-Mancebo ◽  
Manuel Ocaña ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Near Infrared ◽  
Sol Gel ◽  
Upconversion Nanoparticles ◽  
X Ray ◽  
Mesoporous Organosilica ◽  
The Matrix ◽  
X Ray Computed ◽  
Mesoporous Organosilicas ◽  
Cancer Theranostics

(1) Background: Nanomedicine has recently emerged as a promising field, particularly for cancer theranostics. In this context, nanoparticles designed for imaging and therapeutic applications are of interest. We, therefore, studied the encapsulation of upconverting nanoparticles in mesoporous organosilica nanoparticles. Indeed, mesoporous organosilica nanoparticles have been shown to be very efficient for drug delivery, and upconverting nanoparticles are interesting for near-infrared and X-ray computed tomography imaging, depending on the matrix used. (2) Methods: Two different upconverting-based nanoparticles were synthesized with Yb3+-Er3+ as the upconverting system and NaYF4 or BaLuF5 as the matrix. The encapsulation of these nanoparticles was studied through the sol-gel procedure with bis(triethoxysilyl)ethylene and bis(triethoxysilyl)ethane in the presence of CTAB. (3) Results: with bis(triethoxysilyl)ethylene, BaLuF5: Yb3+-Er3+, nanoparticles were not encapsulated, but anchored on the surface of the obtained mesoporous nanorods BaLuF5: Yb3+-Er3+@Ethylene. With bis(triethoxysilyl)ethane, BaLuF5: Yb3+-Er3+ and NaYF4: Yb3+-Er3+nanoparticles were encapsulated in the mesoporous cubic structure leading to BaLuF5: Yb3+-Er3+@Ethane and NaYF4: Yb3+-Er3+@Ethane, respectively. (4) Conclusions: upconversion nanoparticles were located on the surface of mesoporous nanorods obtained by hydrolysis polycondensation of bis(triethoxysilyl)ethylene, whereas encapsulation occurred with bis(triethoxysilyl)ethane. The later nanoparticles NaYF4: Yb3+-Er3+@Ethane or BaLuF5: Yb3+-Er3+@Ethane were promising for applications with cancer cell imaging or X-ray-computed tomography respectively.

scholarly journals Bimodal Nd-Doped LuVO4 Nanoprobes Functionalized with Polyacrilic Acid for X-Ray Computed Tomography and NIR Luminescent Imaging

Nanomaterials ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 149 ◽  
Author(s):  
Nuria O Nuñez ◽  
Fernando Cussó ◽  
Eugenio Cantelar ◽  
Beatriz Martin-Gracia ◽  
Jesús M de la Fuente ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Colloidal Stability ◽  
Near Infrared ◽  
High Cell ◽  
X Ray ◽  
Time In Literature ◽  
Potential Applications ◽  
Intense Luminescence ◽  
X Ray Computed ◽  
First Time

Uniform Nd3+-doped LuVO4 nanophosphors have been synthesized for the first time in literature by using a poliol-based method at 120 °C from Nd3+ and vanadate precursors. After optimizing the Nd doping level, these phosphors present intense luminescence in the near-infrared biological windows. The X-ray attenuation capacity of the optimum nanophosphor has been found to be higher than that of a commercial X-ray computed tomography contrast agent. After surface coating with polyacrylic acid, such nanoparticles present high colloidal stability in physiological pH medium and high cell viability. Because of these properties, the developed Nd3+-doped LuVO4 nanoparticles have potential applications as a bimodal probe for NIR luminescent bioimaging and X-ray computed tomography.

Photosensitizer loaded PEG-MoS2–Au hybrids for CT/NIRF imaging-guided stepwise photothermal and photodynamic therapy

2017 ◽  
Vol 5 (12) ◽  
pp. 2286-2296 ◽  
Author(s):  
Li Liu ◽  
Jinping Wang ◽  
Xiaoxiao Tan ◽  
Xiaojuan Pang ◽  
Qing You ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Photodynamic Therapy ◽  
Gold Nanoparticle ◽  
Molybdenum Disulfide ◽  
Near Infrared ◽  
X Ray ◽  
Nirf Imaging ◽  
X Ray Computed ◽  
Molybdenum Disulfide Nanosheets ◽  
Near Infrared Fluorescence Imaging

We develop X-ray computed tomography/near-infrared fluorescence imaging for visually guiding the photothermal/photodynamic therapy of antitumor nanocomposites (PEG-MoS2–Au–Ce6), by adsorbing chlorin e6 to the gold nanoparticle-decorated molybdenum disulfide nanosheets.

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