Double-mesoporous core–shell nanosystems based on platinum nanoparticles functionalized with lanthanide complexes for in vivo magnetic resonance imaging and photothermal therapy

Nanoscale ◽  
2017 ◽  
Vol 9 (41) ◽  
pp. 16012-16023 ◽  
Author(s):  
Lei Zhao ◽  
Xiaoqian Ge ◽  
Guihua Yan ◽  
Xiao Wang ◽  
Pengfei Hu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Platinum Nanoparticles ◽  
Photothermal Therapy ◽  
Lanthanide Complexes ◽  
Core Shell ◽  
Resonance Imaging

A double-mesoporous core–shell nanosystem based on Pt NPs was firstly developed using a facile strategy and displayed excellent PTT and MRI in vivo.

scholarly journals Silica-Coated Fe3O4 Nanoparticles as a Bifunctional Agent for Magnetic Resonance Imaging and ZnII Fluorescent Sensing

2021 ◽  
Vol 20 ◽  
pp. 153303382110365
Author(s):  
Lin Qiu ◽  
Shuwen Zhou ◽  
Ying Li ◽  
Wen Rui ◽  
Pengfei Cui ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agent ◽  
Quantum Interference ◽  
Inductively Coupled Plasma ◽  
Fluorescence Emission ◽  
Mri Contrast Agent ◽  
Core Shell ◽  
Resonance Imaging

Bifunctional magnetic/fluorescent core-shell silica nanospheres (MNPs) encapsulated with the magnetic Fe3O4 core and a derivate of 8-amimoquinoline (N-(quinolin-8-yl)-2-(3-(triethoxysilyl) propylamino) acetamide) (QTEPA) into the shell were synthesized. These functional MNPs were prepared with a modified stöber method and the formed Fe3O4@SiO2-QTEPA core-shell nanocomposites are biocompatible, water-dispersible, and stable. These prepared nanoparticles were characterized by X-ray power diffraction (XRD), transmission electron microscopy (TEM), thermoelectric plasma Quad II inductively coupled plasma mass spectrometry (ICP-MS), superconducting quantum interference device (SQUID), TG/DTA thermal analyzer (TGA) and Fourier transform infrared spectroscopy (FTIR). Further application of the nanoparticles in detecting Zn2+ was confirmed by the fluorescence experiment: the nanosensor shows high selectivity and sensitivity to Zn2+ with a 22-fold fluorescence emission enhancement in the presence of 10 μM Zn2+. Moreover, the transverse relaxivity measurements show that the core-shell MNPs have T2 relaxivity (r2) of 155.05 mM−1 S−1 based on Fe concentration on the 3.0 T scanner, suggesting that the compound can be used as a negative contrast agent for MRI. Further in vivo experiments showed that these MNPs could be used as MRI contrast agent. Therefore, the new nanosensor provides the dual modality of magnetic resonance imaging and optical imaging.

scholarly journals Polydopamine coated manganese oxide nanoparticles with ultrahigh relaxivity as nanotheranostic agents for magnetic resonance imaging guided synergetic chemo-/photothermal therapy

2016 ◽  
Vol 7 (11) ◽  
pp. 6695-6700 ◽  
Author(s):  
Xing Ding ◽  
Jianhua Liu ◽  
Junqi Li ◽  
Fan Wang ◽  
Yinghui Wang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Manganese Oxide ◽  
Photothermal Therapy ◽  
Oxide Nanoparticles ◽  
Core Shell ◽  
Resonance Imaging ◽  
Manganese Oxide Nanoparticles ◽  
Mri Guided

A multifunctional core/shell nanotheranostic platform was constructed which could offer MRI guided combinational chemotherapy and photothermal therapy for cancer.

Albumin-Bioinspired Gd:CuS Nanotheranostic Agent for In Vivo Photoacoustic/Magnetic Resonance Imaging-Guided Tumor-Targeted Photothermal Therapy

ACS Nano ◽  
2016 ◽  
Vol 10 (11) ◽  
pp. 10245-10257 ◽  
Author(s):  
Weitao Yang ◽  
Weisheng Guo ◽  
Wenjun Le ◽  
Guoxian Lv ◽  
Fuhe Zhang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Photothermal Therapy ◽  
Resonance Imaging

Bioconjugates of versatile β-diketonate–lanthanide complexes as probes for time-gated luminescence and magnetic resonance imaging of cancer cells in vitro and in vivo

2021 ◽  
Vol 9 (14) ◽  
pp. 3161-3167
Author(s):  
Bo Song ◽  
Xinyi Wen ◽  
Xinyue Zhang ◽  
Qi Liu ◽  
Hua Ma ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Cancer Cells ◽  
Lanthanide Complexes ◽  
Tumor Targeting ◽  
Resonance Imaging

Multifunctional bioconjugates of lanthanide complexes for tumor-targeting time-gated luminescence and magnetic resonance imaging in vitro and in vivo.

Fe-doped copper sulfide nanoparticles for in vivo magnetic resonance imaging and simultaneous photothermal therapy

2019 ◽  
Vol 30 (41) ◽  
pp. 415101 ◽  
Author(s):  
Lei Wang ◽  
Xiaofei Xu ◽  
Xingguo Mu ◽  
Qinghe Han ◽  
Jianhua Liu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Copper Sulfide ◽  
Photothermal Therapy ◽  
Resonance Imaging
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