scholarly journals Biocompatible and blood–brain barrier permeable carbon dots for inhibition of Aβ fibrillation and toxicity, and BACE1 activity

Nanoscale ◽  
2017 ◽  
Vol 9 (35) ◽  
pp. 12862-12866 ◽  
Author(s):  
Xu Han ◽  
Zhifeng Jing ◽  
Wei Wu ◽  
Bing Zou ◽  
Zhili Peng ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Carbon Dots ◽  
Brain Barrier ◽  
Oligomer Formation ◽  
Blood Brain ◽  
Bace1 Activity ◽  
Toxic Oligomer

The blood–brain barrier permeable C-Dots can deactivate the BACE1 and further inhibit Aβ fibrillation and toxic oligomer formation.

scholarly journals Crossing the blood–brain–barrier with transferrin conjugated carbon dots: A zebrafish model study

2016 ◽  
Vol 145 ◽  
pp. 251-256 ◽  
Author(s):  
Shanghao Li ◽  
Zhili Peng ◽  
Julia Dallman ◽  
James Baker ◽  
Abdelhameed M. Othman ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Carbon Dots ◽  
Brain Barrier ◽  
Zebrafish Model ◽  
Blood Brain ◽  
Model Study

scholarly journals Carbon Dots: A Future Blood–Brain Barrier Penetrating Nanomedicine and Drug Nanocarrier

2021 ◽  
Vol Volume 16 ◽  
pp. 5003-5016
Author(s):  
Wei Zhang ◽  
Ganesh Sigdel ◽  
Keenan J Mintz ◽  
Elif S Seven ◽  
Yiqun Zhou ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Carbon Dots ◽  
Brain Barrier ◽  
Blood Brain

scholarly journals Tryptophan carbon dots and their ability to cross the blood-brain barrier

2019 ◽  
Vol 176 ◽  
pp. 488-493 ◽  
Author(s):  
Keenan J. Mintz ◽  
Guillaume Mercado ◽  
Yiqun Zhou ◽  
Yiwen Ji ◽  
Sajini D. Hettiarachchi ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Carbon Dots ◽  
Brain Barrier ◽  
Blood Brain

Nontoxic amphiphilic carbon dots as promising drug nanocarriers across the blood–brain barrier and inhibitors of β-amyloid

Nanoscale ◽  
2019 ◽  
Vol 11 (46) ◽  
pp. 22387-22397 ◽  
Author(s):  
Yiqun Zhou ◽  
Piumi Y. Liyanage ◽  
Dinesh Devadoss ◽  
Linda Rebeca Rios Guevara ◽  
Ling Cheng ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Blood Brain Barrier ◽  
Carbon Dots ◽  
Brain Barrier ◽  
Blood Brain ◽  
Β Amyloid ◽  
Amyloid P ◽  
Drug Nanocarriers

Unique nontoxic amphiphilic carbon dots have been developed as an excellent drug nanocarrier targeting the Alzheimer's disease by crossing the blood-brain barrier (BBB) while inhibiting the production of β-amyloid.

Conformationally Constrained Peptide Drugs Targeted at the Blood-Brain Barrier

1995 ◽  
Author(s):  
Thomas P. Davis ◽  
Thomas J. Abbruscato ◽  
Elizabeth Brownson ◽  
Victor J. Hruby
Keyword(s):  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Peptide Drugs ◽  
Conformationally Constrained ◽  
Blood Brain
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