scholarly journals Selective detection of inorganic phosphates in live cells based on a responsive fluorescence probe

2017 ◽  
Vol 41 (18) ◽  
pp. 9623-9630 ◽  
Author(s):  
Huan Feng ◽  
Yue Wang ◽  
Hongmin Jia ◽  
Run Zhang ◽  
Qian Han ◽  
...  
Keyword(s):  
Inorganic Phosphate ◽  
Fluorescence Probe ◽  
Live Cells ◽  
Selective Detection ◽  
Phosphate Detection ◽  
Inorganic Phosphates

A new activatable fluorescence probe has been designed and synthesized for inorganic phosphate detection in buffer and live cells.

A red-NIR emissive probe for the selective detection of albumin in urine samples and live cells

2017 ◽  
Vol 15 (7) ◽  
pp. 1584-1588 ◽  
Author(s):  
K. Rajasekhar ◽  
Chaithra J. Achar ◽  
Thimmaiah Govindaraju
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Gel Electrophoresis ◽  
Fluorescence Probe ◽  
Urine Samples ◽  
Live Cells ◽  
Selective Detection ◽  
Nir Fluorescence ◽  
Emissive Probe

A red-NIR fluorescence probe (TG-SA) has been designed, synthesised and its utility is demonstrated for staining human serum albumin (HSA) in gel electrophoresis, quantification of HSA in clinical urine samples and monitoring serum albumin homeostasis in live cells.

A Far-Red-Emitting Fluorescence Probe for Sensitive and Selective Detection of Peroxynitrite in Live Cells and Tissues

2017 ◽  
Vol 89 (20) ◽  
pp. 10924-10931 ◽  
Author(s):  
Di Wu ◽  
Jae-Chan Ryu ◽  
Youn Wook Chung ◽  
Dayoung Lee ◽  
Ji-Hwan Ryu ◽  
...  
Keyword(s):  
Fluorescence Probe ◽  
Live Cells ◽  
Selective Detection

A naphthalimide based PET probe with Fe3+ selective detection ability: theoretical and experimental study

The Analyst ◽  
2014 ◽  
Vol 139 (24) ◽  
pp. 6352-6356 ◽  
Author(s):  
Narendra Reddy Chereddy ◽  
M. V. Niladri Raju ◽  
Peethani Nagaraju ◽  
Venkat Raghavan Krishnaswamy ◽  
Purna Sai Korrapati ◽  
...  
Keyword(s):  
Experimental Study ◽  
Live Cells ◽  
Selective Detection ◽  
Aqueous Samples ◽  
Detection Ability ◽  
Turn On ◽  
Fluorescence Turn On

A naphthalimide based Fe3+ selective fluorescence ‘turn-on’ probe that operates based on a PET mechanism has been synthesized, and its application in the detection of Fe3+ ions in aqueous samples and in live cells is explored.

Cellular membrane-anchored fluorescent probe with aggregation-induced emission characteristics for selective detection of Cu2+ ions

2017 ◽  
Vol 196 ◽  
pp. 377-393 ◽  
Author(s):  
Danni Liu ◽  
Shenglu Ji ◽  
Heran Li ◽  
Liang Hong ◽  
Deling Kong ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Cell Membrane ◽  
Water Solubility ◽  
Live Cells ◽  
Probe Design ◽  
Specific Cell ◽  
Selective Detection ◽  
High Concentration ◽  
Aggregation Induced Emission ◽  
Emissive Probes

The exploration of advanced fluorescent probes that can detect divalent copper (Cu2+) in aqueous environments and even in live organisms is particularly valuable for understanding the occurrence and development of Cu2+-related diseases. In this work, we report the design and synthesis of an aggregation-induced emission luminogen (AIEgen)-based probe (TPE-Py-EEGTIGYG) by integrating an AIEgen, TPE-Py, with a peptide, EEGTIGYG, which can selectively detect Cu2+ in both aqueous solution and live cells. Peptide EEGTIGYG has dual functionality in the probe design, namely improving water solubility and providing specific cell membrane-binding ability. TPE-Py-EEGTIGYG can self-assemble into nanoaggregates at high concentration in aqueous solution (e.g., 25 μM), which possess large fluorescence output due to the restriction of intramolecular rotation of the phenyl rings on TPE-Py. The fluorescence of the TPE-Py-EEGTIGYG nanoaggregates can be significantly quenched by Cu2+ but not by other metal ions, achieving the selective detection of Cu2+ in aqueous media. Furthermore, TPE-Py-EEGTIGYG can exist as a molecular species and is very weakly fluorescent in dilute aqueous solution (e.g., 5 μM), but can however largely switch on its fluorescence upon specifically anchoring onto the cell membrane. The emissive probes on the cell membrane can be used for the detection of Cu2+ ions that move in and out of cells with a fluorescence “turn-off” mode.

Reversible Off–On Fluorescence Probe for Hypoxia and Imaging of Hypoxia–Normoxia Cycles in Live Cells

2012 ◽  
Vol 134 (48) ◽  
pp. 19588-19591 ◽  
Author(s):  
Shodai Takahashi ◽  
Wen Piao ◽  
Yuriko Matsumura ◽  
Toru Komatsu ◽  
Tasuku Ueno ◽  
...  
Keyword(s):  
Fluorescence Probe ◽  
Live Cells
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