Integration of oxidative arylation with sulfonyl migration: one-pot tandem synthesis of densely functionalized (NH)-pyrroles

2017 ◽  
Vol 41 (17) ◽  
pp. 8791-8803 ◽  
Author(s):  
Joydev K. Laha ◽  
Shubhra Sharma ◽  
Rohan A. Bhimpuria ◽  
Neetu Dayal ◽  
Gurudutt Dubey ◽  
...  
Keyword(s):  
One Pot ◽  
Alkyl Aryl ◽  
One Pot Synthesis ◽  
Palladium Catalyzed ◽  
First Time ◽  
Tandem Synthesis

A one-pot synthesis of 2-aryl-3-alkyl/aryl-sulfonyl-(NH)-pyrroles from N-sulfonylpyrroles, developed for the first time, via palladium-catalyzed oxidative C-2 arylation followed by sulfonyl migration is described.

Palladium catalyzed decarboxylative acylation of arylboronic acid with ethyl cyanoacetate as a new acylating agent: synthesis of alkyl aryl ketones

2015 ◽  
Vol 39 (11) ◽  
pp. 8763-8770 ◽  
Author(s):  
Md Yousuf ◽  
Tuluma Das ◽  
Susanta Adhikari
Keyword(s):  
Ethyl Cyanoacetate ◽  
Acylating Agent ◽  
Arylboronic Acid ◽  
One Pot ◽  
Alkyl Aryl ◽  
One Pot Synthesis ◽  
Aryl Ketones ◽  
Palladium Catalyzed

The versatile, one-pot synthesis of a series of alkyl aryl ketones is described using ethyl cyanoacetate as a new acylating agent.

scholarly journals Palladium-catalyzed arylation of linear and cyclic polyamines

2004 ◽  
Vol 76 (9) ◽  
pp. 1605-1619 ◽  
Author(s):  
Irina P. Beletskaya ◽  
A. D. Averin
Keyword(s):  
Phosphine Ligands ◽  
One Pot ◽  
Face To Face ◽  
One Pot Synthesis ◽  
Catalytic Amination ◽  
The Face ◽  
Palladium Catalyzed ◽  
First Time

Synthetic protocols for the palladium-catalyzed arylation of various linear and cyclic polyamines and polyoxapolyamines has been worked out. Pd(0) and Pd(II)complexes with such phosphine ligands as dppf, BINAP, PPF-OMe, P(tBu)3,2-ditert-butylphosphino-1,1'-biphenyl have been explored in the catalytic amination reactions. Monoamination of chloro-, bromo-, and iodoarenes with di-, tri-, and tetraamines have been carried out, conditions for di- and polyarylation of linear polyamines have been elaborated. Successful arylation of 1,4,7,10-tetraazacyclododecane (cyclene) and 1,4,8,11-tetraazacyclotetradecane (cyclam) have been conducted. Intramolecular diamination of dihaloarenes such as 1,2-dibromobenzene, 2,6-dichlorobromobenzene, 1,3-dibromobenzene, 1,8-dichloroanthracene, 1,8-dichloroanthraquinone, 1,5-dichloroanthracene, and 1,5-dichloroanthraquinone afforded corresponding polyazamacrocycles containing arene moieties. For the first time, a convenient one-pot synthesis of the face-to-face arranged bismacrocyclic systems has been carried out.

An Expeditious One-Pot Three-Component Synthesis of 4-Aryl-3,4-dihydrobenzo[g] quinoline-2,5,10(1H)-triones under Green Conditions

2020 ◽  
Vol 23 (23) ◽  
pp. 2626-2634
Author(s):  
Saiedeh Kamalifar ◽  
Hamzeh Kiyani
Keyword(s):  
Reaction Medium ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
One Pot ◽  
One Pot Synthesis ◽  
Substituted Benzaldehydes ◽  
High Yields ◽  
First Time ◽  
Green Conditions

: An efficient and facial one-pot synthesis of 4-aryl-3,4-dihydrobenzo[g]quinoline- 2,5,10(1H)-triones was developed for the first time. The process proceeded via the three-component cyclocondensation of 2-amino-1,4-naphthoquinone with Meldrum’s acid and substituted benzaldehydes under green conditions. The fused 3,4-dihydropyridin-2(1H)- one-ring naphthoquinones have been synthesized with good to high yields in refluxing ethanol as a green reaction medium. This protocol is simple and effective as well as does not involve the assistance of the catalyst, additive, or hazardous solvents.

ChemInform Abstract: Nanodomain Cubic Cuprous Oxide as Reusable Catalyst in One-Pot Synthesis of 3-Alkyl/Aryl-3- (pyrrole-2-yl/indole-3-yl)-2-phenyl-2,3-dihydro-isoindolinones in Aqueous Medium.

ChemInform ◽  
2014 ◽  
Vol 45 (41) ◽  
pp. no-no
Author(s):  
Swarbhanu Sarkar ◽  
Nivedita Chatterjee ◽  
Manas Roy ◽  
Rammyani Pal ◽  
Sabyasachi Sarkar ◽  
...  
Keyword(s):  
Aqueous Medium ◽  
Cuprous Oxide ◽  
Reusable Catalyst ◽  
One Pot ◽  
Alkyl Aryl ◽  
One Pot Synthesis

Pt NPs@GO as a highly efficient and reusable catalyst for one-pot synthesis of acridinedione derivatives

RSC Advances ◽  
2015 ◽  
Vol 5 (61) ◽  
pp. 49295-49300 ◽  
Author(s):  
Handan Pamuk ◽  
Burak Aday ◽  
Fatih Şen ◽  
Muharrem Kaya
Keyword(s):  
Aromatic Aldehydes ◽  
Reusable Catalyst ◽  
One Pot ◽  
Highly Efficient ◽  
One Pot Synthesis ◽  
First Time

Pt NPs@GO has been used for the first time for synthesizing acridinedione from dimedone, aromatic aldehydes and various amines as a catalyst.

Catalyst-Free One-Pot Synthesis of Novel Heteroarylamine Substituted Furo[3,2-c]coumarins

Synlett ◽  
2018 ◽  
Vol 29 (12) ◽  
pp. 1589-1592 ◽  
Author(s):  
Abolfazl Olyaei ◽  
Mahnaz Saraei ◽  
Reyhaneh Khoeiniha
Keyword(s):  
Michael Addition ◽  
Aldol Condensation ◽  
Ring Closure ◽  
Dehydration Reaction ◽  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Tandem Process ◽  
First Time

A high-yielding cyclocondensation of 4-hydroxycoumarin, phenylglyoxal monohydrate, and heteroarylamines proceeds without catalysis, which gives novel functionalized furo[3,2-c]coumarins and heteroarylamino alkylation of coumarin products in acetonitrile under reflux, is reported for the first time. This tandem process involves sequentially an aldol condensation, Michael addition, a ring closure, and dehydration reaction.

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