Arsenite increases Cyclin D1 expression through coordinated regulation of the Ca2+/NFAT2 and NF-κB pathwaysviaERK/MAPK in a human uroepithelial cell line

Metallomics ◽  
2018 ◽  
Vol 10 (3) ◽  
pp. 486-495 ◽  
Author(s):  
Jieyu Liu ◽  
Peiyu Jin ◽  
Xiaoli Lin ◽  
Qing Zhou ◽  
Fei Wang ◽  
...  

Understanding the effects of Ca2+/NFAT and NF-κB signals on the regulation of cyclin D1 expression in arsenite-treated bladder cells.

The Analyst ◽  
2017 ◽  
Vol 142 (8) ◽  
pp. 1244-1257 ◽  
Author(s):  
A. Mignolet ◽  
V. Mathieu ◽  
E. Goormaghtigh

FTIR-based classification of the effect of polyphenols on a breast cancer cell line.


RSC Advances ◽  
2017 ◽  
Vol 7 (9) ◽  
pp. 5282-5296 ◽  
Author(s):  
Marija S. Jeremić ◽  
Hubert Wadepohl ◽  
Vesna V. Kojić ◽  
Dimitar S. Jakimov ◽  
Ratomir Jelić ◽  
...  

Two new Rh(iii)–ed3a complexes [Rh(ed3a)(OH2)]·H2O and Na[Rh(ed3a)Cl]·H2O have shown good antitumor activity, especially against HeLa cell line.


RSC Advances ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 3162-3167
Author(s):  
Ya-jing Wang ◽  
Nan Ma ◽  
Chun-yue Liu ◽  
Yi-xuan Feng ◽  
Feng-xiang Zhang ◽  
...  

Two new xanthones, oxisterigmatocystins J and K, and two new anthraquinones, versicolorins D and E, were characterized from the fungus Penicillium sp. Compounds 4 and 5 showed significant cytotoxic activities against HL-60 cell line.


2021 ◽  
Author(s):  
Daehun Park ◽  
Pietro De Camilli

This cell line was described and characterized in the following paper: Ferguson, S.M., Raimondi, A., Paradise, S., Shen, H., Mesaki, K., Ferguson, A., Destaing, O., Ko, G., Takasaki, J., Cremona, O., O’Toole, E., De Camilli P. Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits. Developmental Cell 17, 811-822, 2009. PMID: 20059951]. This procedure describes tamoxifeninducible KO method using this cell line.


2020 ◽  
Vol 8 (18) ◽  
pp. 4016-4028 ◽  
Author(s):  
Alexander Morlando ◽  
Marcela Chaki Borrás ◽  
Yaser Rehman ◽  
Shahnaz Bakand ◽  
Philip Barker ◽  
...  

Low photocatalytic CeO2/TiO2 nanocomposite particles with high UV attenuation and reduced ROS generation for application in sunscreen products.


RSC Advances ◽  
2019 ◽  
Vol 9 (50) ◽  
pp. 29273-29292 ◽  
Author(s):  
Singireddi Srinivasarao ◽  
Adinarayana Nandikolla ◽  
Shashidhar Nizalapur ◽  
Tsz Tin Yu ◽  
Sravani Pulya ◽  
...  

Out of 40 benzimdazoles, 12 exhibited potent QSI activity against P. aeruginosa6p, most active QSI is docked to LasR and is less toxic against HEK 293 cell line.


Blood ◽  
1999 ◽  
Vol 93 (4) ◽  
pp. 1330-1337 ◽  
Author(s):  
Domenica Ronchetti ◽  
Palma Finelli ◽  
Raffaella Richelda ◽  
Luca Baldini ◽  
Mariano Rocchi ◽  
...  

Abstract The t(11;14)(q13;q32) chromosomal translocation, which is the hallmark of mantle cell lymphoma (MCL), is found in approximately 30% of multiple myeloma (MM) tumors with a 14q32 translocation. Although the overexpression of cyclin D1 has been found to be correlated with MM cell lines carrying the t(11;14), rearrangements of theBCL-1/cyclin D1 regions frequently involved in MCL rarely occur in MM cell lines or primary tumors. To test whether specific 11q13 breakpoint clusters may occur in MM, we investigated a representative panel of primary tumors by means of Southern blot analysis using probes derived from MM-associated 11q13 breakpoints. To this end, we first cloned the breakpoints and respective germ-line regions from a primary tumor and the U266 cell line, as well as the germ-line region from the KMS-12 cell line. DNA from 50 primary tumors was tested using a large panel of probes, but a rearrangement was detected in only one case using the KMS-12 breakpoint probe. Our results confirm previous findings that the 11q13 breakpoints in MM are scattered throughout the 11q13 region encompassing the cyclinD1 gene, thus suggesting the absence of 11q13 breakpoint clusters in MM.


2020 ◽  
Vol 44 (5) ◽  
pp. 2166-2179 ◽  
Author(s):  
Elavarasan Nagaraj ◽  
Prakash Shanmugam ◽  
Kokila Karuppannan ◽  
Thirunavukkarasu Chinnasamy ◽  
Sujatha Venugopal

ZnO/GO nanocomposites were synthesized and their antibacterial activities assessed against various pathogens. They are potential antibacterial materials and significant anticancer activity against the MCF-7 breast cancer cell line compared to the A549 lung cancer cell line.


Sign in / Sign up

Export Citation Format

Share Document