scholarly journals Single layer porous media with entrapped minerals for microscale studies of multiphase flow

Lab on a Chip ◽  
2018 ◽  
Vol 18 (7) ◽  
pp. 1094-1104 ◽  
Author(s):  
R. W. Liefferink ◽  
A. Naillon ◽  
D. Bonn ◽  
M. Prat ◽  
N. Shahidzadeh
Keyword(s):  
Porous Media ◽  
Multiphase Flow ◽  
Single Layer ◽  
Novel Method

We report a novel method for manufacturing single layer porous media in which minerals can be entrapped in a controlled way in order to study their dissolution and recrystallization.

scholarly journals Homogeneous 2D and 3D alignment of cardiomyocyte in dilated cardiomyopathy revealed by intravital heart imaging

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kiyoshi Masuyama ◽  
Tomoaki Higo ◽  
Jong-Kook Lee ◽  
Ryohei Matsuura ◽  
Ian Jones ◽  
...  
Keyword(s):  
Heart Failure ◽  
Dilated Cardiomyopathy ◽  
Cardiac Dysfunction ◽  
Three Dimensional ◽  
Single Layer ◽  
Specific Pattern ◽  
Two Dimensional ◽  
Heart Imaging ◽  
Novel Method ◽  
2D And 3D

AbstractIn contrast to hypertrophic cardiomyopathy, there has been reported no specific pattern of cardiomyocyte array in dilated cardiomyopathy (DCM), partially because lack of alignment assessment in a three-dimensional (3D) manner. Here we have established a novel method to evaluate cardiomyocyte alignment in 3D using intravital heart imaging and demonstrated homogeneous alignment in DCM mice. Whilst cardiomyocytes of control mice changed their alignment by every layer in 3D and position twistedly even in a single layer, termed myocyte twist, cardiomyocytes of DCM mice aligned homogeneously both in two-dimensional (2D) and in 3D and lost myocyte twist. Manipulation of cultured cardiomyocyte toward homogeneously aligned increased their contractility, suggesting that homogeneous alignment in DCM mice is due to a sort of alignment remodelling as a way to compensate cardiac dysfunction. Our findings provide the first intravital evidence of cardiomyocyte alignment and will bring new insights into understanding the mechanism of heart failure.

scholarly journals An open-source toolbox for multiphase flow in porous media

2015 ◽  
Vol 187 ◽  
pp. 217-226 ◽  
Author(s):  
P. Horgue ◽  
C. Soulaine ◽  
J. Franc ◽  
R. Guibert ◽  
G. Debenest
Keyword(s):  
Porous Media ◽  
Multiphase Flow ◽  
Open Source ◽  
Flow In Porous Media

scholarly journals A Fractal Model for Predicting the Relative Permeability of Rough-Walled Fractures

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Zuyang Ye ◽  
Wang Luo ◽  
Shibing Huang ◽  
Yuting Chen ◽  
Aiping Cheng
Keyword(s):  
Porous Media ◽  
Multiphase Flow ◽  
Relative Permeability ◽  
Fractal Model ◽  
Numerical Results ◽  
Flow Paths ◽  
Capillary Model ◽  
Lognormal Distributions ◽  
Fractal Characteristics ◽  
Aperture Distribution

The relative permeability and saturation relationships through fractures are fundamental for modeling multiphase flow in underground geological fractured formations. In contrast to the traditional straight capillary model from porous media, the realistic flow paths in rough-walled fractures are tortuous. In this study, a fractal relationship between relative permeability and saturation of rough-walled fractures is proposed associated with the fractal characteristics of tortuous parallel capillary plates, which can be generalized to several existing models. Based on the consideration that the aperture distribution of rough-walled fracture can be represented by Gaussian and lognormal distributions, aperture-based expressions between relative permeability and saturation are explicitly derived. The developed relationships are validated by the experimental observations on Gaussian distributed fractures and numerical results on lognormal distributed fractures, respectively.

Experimental observations of multiphase flow in heterogeneous porous media

1989 ◽  
Vol 5 (1) ◽  
pp. 83-95 ◽  
Author(s):  
Bernard H. Kueper ◽  
Wesley Abbott ◽  
Graham Farquhar
Keyword(s):  
Porous Media ◽  
Multiphase Flow ◽  
Heterogeneous Porous Media
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