scholarly journals Recent progress of particle migration in viscoelastic fluids

Lab on a Chip ◽  
2018 ◽  
Vol 18 (4) ◽  
pp. 551-567 ◽  
Author(s):  
Dan Yuan ◽  
Qianbin Zhao ◽  
Sheng Yan ◽  
Shi-Yang Tang ◽  
Gursel Alici ◽  
...  
Keyword(s):  
Recent Progress ◽  
Viscoelastic Fluids ◽  
Lab On A Chip ◽  
Particle Migration

In this review, we discuss the up-to-date progress of particle migration in viscoelastic fluids mainly from the aspect of applications, laying out a comprehensive perspective on their potential in future lab-on-a-chip platforms.

Recent progress in lab-on-a-chip for pharmaceutical analysis and pharmacological/toxicological test

2019 ◽  
Vol 117 ◽  
pp. 215-230 ◽  
Author(s):  
Yongjian Ai ◽  
Feng Zhang ◽  
Chenlong Wang ◽  
Ruoxiao Xie ◽  
Qionglin Liang
Keyword(s):  
Pharmaceutical Analysis ◽  
Recent Progress ◽  
Lab On A Chip ◽  
Toxicological Test

Rheometry-on-a-chip: measuring the relaxation time of a viscoelastic liquid through particle migration in microchannel flows

Lab on a Chip ◽  
2015 ◽  
Vol 15 (3) ◽  
pp. 783-792 ◽  
Author(s):  
Francesco Del Giudice ◽  
Gaetano D'Avino ◽  
Francesco Greco ◽  
Ilaria De Santo ◽  
Paolo A. Netti ◽  
...  
Keyword(s):  
Relaxation Time ◽  
Viscoelastic Fluids ◽  
Viscoelastic Liquid ◽  
Particle Migration ◽  
Microchannel Flows ◽  
Novel Method

A novel method to estimate the relaxation time of viscoelastic fluids, down to milliseconds, is here proposed.

scholarly journals Recent Progress in Lab-On-a-Chip Systems for the Monitoring of Metabolites for Mammalian and Microbial Cell Research

Sensors ◽  
2019 ◽  
Vol 19 (22) ◽  
pp. 5027 ◽  
Author(s):  
Esma Dervisevic ◽  
Kellie L. Tuck ◽  
Nicolas H. Voelcker ◽  
Victor J. Cadarso
Keyword(s):  
Cell Biology ◽  
Recent Progress ◽  
Relevant Literature ◽  
Lab On A Chip ◽  
Microbial Cell ◽  
Future Perspectives ◽  
Specific Context ◽  
The Future ◽  
Metabolite Detection ◽  
Biology Research

Lab-on-a-chip sensing technologies have changed how cell biology research is conducted. This review summarises the progress in the lab-on-a-chip devices implemented for the detection of cellular metabolites. The review is divided into two subsections according to the methods used for the metabolite detection. Each section includes a table which summarises the relevant literature and also elaborates the advantages of, and the challenges faced with that particular method. The review continues with a section discussing the achievements attained due to using lab-on-a-chip devices within the specific context. Finally, a concluding section summarises what is to be resolved and discusses the future perspectives.

scholarly journals Effects of Ionic Strength on Lateral Particle Migration in Shear-Thinning Xanthan Gum Solutions

Micromachines ◽  
2019 ◽  
Vol 10 (8) ◽  
pp. 535 ◽  
Author(s):  
Mira Cho ◽  
Sun Ok Hong ◽  
Seung Hak Lee ◽  
Kyu Hyun ◽  
Ju Min Kim
Keyword(s):  
Ionic Strength ◽  
Rheological Properties ◽  
Viscoelastic Fluid ◽  
Xanthan Gum ◽  
Viscoelastic Fluids ◽  
Shear Thinning ◽  
Particle Migration ◽  
Cell Counting ◽  
Contour Length ◽  
Wide Range

Viscoelastic fluids, including particulate systems, are found in various biological and industrial systems including blood flow, food, cosmetics, and electronic materials. Particles suspended in viscoelastic fluids such as polymer solutions migrate laterally, forming spatially segregated streams in pressure-driven flow. Viscoelastic particle migration was recently applied to microfluidic technologies including particle counting and sorting and the micromechanical measurement of living cells. Understanding the effects on equilibrium particle positions of rheological properties of suspending viscoelastic fluid is essential for designing microfluidic applications. It has been considered that the shear-thinning behavior of viscoelastic fluid is a critical factor in determining the equilibrium particle positions. This work presents the lateral particle migration in two different xanthan gum-based viscoelastic fluids with similar shear-thinning viscosities and the linear viscoelastic properties. The flexibility and contour length of the xanthan gum molecules were tuned by varying the ionic strength of the solvent. Particles suspended in flexible and short xanthan gum solution, dissolved at high ionic strength, migrated toward the corners in a square channel, whereas particles in the rigid and long xanthan gum solutions in deionized water migrated toward the centerline. This work suggests that the structural properties of polymer molecules play significant roles in determining the equilibrium positions in shear-thinning fluids, despite similar bulk rheological properties. The current results are expected to be used in a wide range of applications such as cell counting and sorting.

scholarly journals Particle migration and single-line particle focusing in microscale pipe flow of viscoelastic fluids

RSC Advances ◽  
2014 ◽  
Vol 4 (7) ◽  
pp. 3512-3520 ◽  
Author(s):  
Kyung Won Seo ◽  
Hyeok Jun Byeon ◽  
Hyung Kyu Huh ◽  
Sang Joon Lee
Keyword(s):  
Pipe Flow ◽  
Viscoelastic Fluids ◽  
Particle Migration ◽  
Single Line ◽  
Particle Focusing
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