scholarly journals A simple and highly sensitive spectroscopic fluorescence-detection system for multi-channel plastic-microchip electrophoresis based on side-entry laser-beam zigzag irradiation

Lab on a Chip ◽  
2017 ◽  
Vol 17 (13) ◽  
pp. 2235-2242 ◽  
Author(s):  
Takashi Anazawa ◽  
Yuichi Uchiho ◽  
Takahide Yokoi ◽  
George Chalkidis ◽  
Motohiro Yamazaki

Fluorescence from eight A channels and Raman-scattered light from seven B channels, induced by a side-entry laser beam, were simultaneously, uniformly, and spectroscopically detected.

Lab on a Chip ◽  
2011 ◽  
Vol 11 (9) ◽  
pp. 1664 ◽  
Author(s):  
Gihan Ryu ◽  
Jingsong Huang ◽  
Oliver Hofmann ◽  
Claire A. Walshe ◽  
Jasmine Y. Y. Sze ◽  
...  

Optik ◽  
2015 ◽  
Vol 126 (19) ◽  
pp. 2087-2089 ◽  
Author(s):  
Zhen Li ◽  
Jinsong Zhang ◽  
Hong Hu ◽  
Ruyi Wan ◽  
Youwei Yao

2020 ◽  
Vol 56 (16) ◽  
pp. 2423-2426 ◽  
Author(s):  
Wenmei Zhang ◽  
Lei Liu ◽  
Qi Zhang ◽  
Dongtang Zhang ◽  
Qin Hu ◽  
...  

We developed a highly sensitive laser-induced fluorescence detection system, involving visual and real-time imaging focusing instead of the use of fluorescent reagents, for the detection of analytes in nanocapillaries.


1994 ◽  
Vol 48 (12) ◽  
pp. 1483-1490 ◽  
Author(s):  
Taggart D. Downare ◽  
Oliver C. Mullins ◽  
Xu Wu

The optimization of a robust fluorescence detection system is described in which both scattered excitation light and collected fluorescence emission from rock, core, or cutting samples are guided by optical fibers. Analysis of solids poses increased difficulties compared to the extensively studied analysis of liquids; large and variable scattered light can lead to substantial reduction of the system dynamic range and to significant optical noise without proper rejection of the scattered source light. In addition, optical component fluorescence must be minimized; optimization and final optical component selections were based upon the system throughput as well as the system dynamic range. The optimized design was found by analysis of the individual system components—specifically, the source, launch objectives, fiber optics, output collimation optics, and filters. A system dynamic range of 5.1 optical density was achieved, and system performance was demonstrated with fluorescence yield measurements on a variety of solid samples.


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