Modeling electrical double-layer effects for microfluidic impedance spectroscopy from 100 kHz to 110 GHz

Lab on a Chip ◽  
2017 ◽  
Vol 17 (15) ◽  
pp. 2674-2681 ◽  
Author(s):  
Charles A. E. Little ◽  
Nathan D. Orloff ◽  
Isaac E. Hanemann ◽  
Christian J. Long ◽  
Victor M. Bright ◽  
...  
Keyword(s):  
Impedance Spectroscopy ◽  
Double Layer ◽  
Electrical Double Layer ◽  
Microfluidic Channels ◽  
Frequency Range ◽  
Broad Frequency Range ◽  
On Chip ◽  
Saline Solutions

On-chip microwave calibrations are used to characterize the electrical-double layer response for saline solutions in microfluidic channels over an extremely broad frequency range.

scholarly journals A label-free aptamer-based nanogap capacitive biosensor with greatly diminished electrode polarization effects

2019 ◽  
Vol 21 (2) ◽  
pp. 681-691 ◽  
Author(s):  
Zahra Ghobaei Namhil ◽  
Cordula Kemp ◽  
Emanuele Verrelli ◽  
Alex Iles ◽  
Nicole Pamme ◽  
...  
Keyword(s):  
Impedance Spectroscopy ◽  
Double Layer ◽  
Electrical Double Layer ◽  
Polarization Effect ◽  
Electrode Polarization ◽  
Label Free ◽  
Polarization Effects ◽  
Solution Interface ◽  
Free Ions ◽  
Capacitive Biosensor

A significant impediment to the use of impedance spectroscopy in bio-sensing is the electrode polarization effect that arises from the movement of free ions to the electrode–solution interface, forming an electrical double layer (EDL).

scholarly journals Assessing the potential of LiPON-based electrical double layer microsupercapacitors for on-chip power storage

2020 ◽  
Vol 451 ◽  
pp. 227786 ◽  
Author(s):  
Valentin Sallaz ◽  
Sami Oukassi ◽  
Frédéric Voiron ◽  
Raphaël Salot ◽  
David Berardan
Keyword(s):  
Double Layer ◽  
Electrical Double Layer ◽  
Power Storage ◽  
On Chip

Electrokinetic-Based Microfluidic Processes in Lab-on-a-Chip Devices

2004 ◽  
Author(s):  
Dongqing Li
Keyword(s):  
Process Control ◽  
Double Layer ◽  
Electrical Double Layer ◽  
Electroosmotic Flow ◽  
Lab On A Chip ◽  
Fundamental Understanding ◽  
On Chip

Most microfluidic processes in lab-on-a-chip devices are electrokinetic processes. Fundamental understanding of the electrokinetic based microfluidic processes is key to the design and process control of lab-on-a-chip devices. This paper will review basics of the electrical double layer field, and three key on-chip microfluidic processes: electroosmotic flow, sample mixing and sample dispensing.

Some aspects of charge transport in Li0.5-xNaxLa0.5TiO3 (x = 0, 0.25) ceramics

2015 ◽  
Vol 08 (06) ◽  
pp. 1550076 ◽  
Author(s):  
Edvardas Kazakevičius ◽  
Algimantas Kežionis ◽  
Tomas Šalkus ◽  
Antanas Feliksas Orliukas ◽  
Oleg Ivanovich V'yunov ◽  
...  
Keyword(s):  
Impedance Spectroscopy ◽  
Charge Transport ◽  
Equivalent Circuit ◽  
Electric Modulus ◽  
Partial Substitution ◽  
Frequency Range ◽  
Broad Frequency Range ◽  
Equivalent Circuit Method

In this work, the influence of partial substitution of Li to Na in Li 0.5 La 0.5 TiO 3 (LLTO) compound was investigated by broad frequency range impedance spectroscopy (IS). The equivalent circuit method was used to relate the electric modulus spectra with confinement of mobile Li ions by rigidly arranged Na in the lattice of LLTO.

Nanotextured Material for Applications in CSF Sample Screening and Characterization

2012 ◽  
Vol 1466 ◽  
Author(s):  
Krishna Vattipalli ◽  
Savindra Brandigampala ◽  
Claire McGraw ◽  
Gaurav Chatterjee ◽  
Srinath Kasturirangan ◽  
...  
Keyword(s):  
Impedance Spectroscopy ◽  
Neurodegenerative Disease ◽  
Double Layer ◽  
Electrical Double Layer ◽  
Protein Misfolding ◽  
Electrochemical Impedance ◽  
Great Promise ◽  
Parkinson’S Diseases ◽  
Specific Association ◽  
High Degree

ABSTRACTNeurodegenerative disease is primarily characterized by protein misfolding and the resultant protein aggregation. Presence of soluble oligomeric aggregates of proteins including various Aβ and α-syn aggregate species can be correlated to the onset and progression of many neurodegenerative diseases. The ability to detect protein misfolding requires the design of a diagnostics assay the will enable molecular level probing. The use of nanoporous ceramic templates enables size based immobilization of the target proteins and by leveraging the principle of “macromolecular crowding” protein association can be mapped with a high degree of resolution. By tailoring the surface functionalization within nanoporous ceramic templates, macromolecular immobilization can be selectively controlled, which in turn significantly enhances the perturbation to the electrical double layer/. The changes to the electrical double layer are measured with a high degree of sensitivity through impedance spectroscopy.Pre symptomatic diagnosis and distinction between Alzheimer’s and Parkinson’s diseases can be achieved by the specific detection and quantification of levels of each of these different toxic protein species in cerebrospinal fluid (CSF). Detection using highly selective morphology specific reagents in conjunction with the ultrasensitive nanoporous electronic biosensor showed the presence of different protein morphologies in human CSF samples. Detection is primarily achieved by identifying the specific association of the protein with its receptor using electrochemical impedance spectroscopy. Furthermore, we show that these morphology specific reagents can readily classify between post-mortem CSF samples from AD, PD and cognitively normal sources. These studies suggest that detection of specific oligomeric aggregate species holds great promise as sensitive biomarkers for neurodegenerative disease.

Conductivity Studies of Schiff Base Ligands Derived from O-Phenylenediamine and Their Co(II) and Zn(II) Complexes

2015 ◽  
Vol 12 (2) ◽  
pp. 13
Author(s):  
Muhamad Faridz Osman ◽  
Karimah Kassim
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Fourier Transform ◽  
Schiff Base ◽  
Nmr Spectroscopy ◽  
Magnetic Resonance ◽  
Impedance Spectroscopy ◽  
Ftir Spectroscopy ◽  
Coordination Complexes ◽  
Frequency Range ◽  
Schiff Base Ligands

The coordination complexes of Co(II) and Zn(II) with Schiff bases derived from o-phenylenediamine and substituted 2-hydroxybenzaldehyde were prepared All compounds were characterized by Fourier transform infrared (FTIR) spectroscopy and Nuclear magnetic resonance (NMR) spectroscopy elemental analyzers. They were analyzed using impedance spectroscopy in the frequency range of 100Hz-1 MHz. LI and L2 showed higher conductivity compared to their metal complexes, which had values of 1.3 7 x 10-7 and 6.13 x 10-8 S/cm respectively. 

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