Selenium enriched dietary supplement rapid screening method using XRF and DART-HRAM-MS for label verification

2017 ◽  
Vol 32 (6) ◽  
pp. 1196-1202 ◽  
Author(s):  
T. A. Hanley ◽  
K. Kubachka ◽  
A. M. Taylor ◽  
S. E. Kern
Keyword(s):  
Dietary Supplements ◽  
Dietary Supplement ◽  
Screening Method ◽  
Rapid Screening ◽  
Rapid Screening Method

Labelled selenium ingredients in dietary supplements can be assessed quickly, in under an hour, using a combination of XRF and DART-HRAM-MS.

Rapid Screening Method in the Identification of 17 Adulterants in Dietary Supplements

2021 ◽  
Vol 84 (3) ◽  
pp. 267-274
Author(s):  
Julia Rodrigues Martins Pastor dos Santos ◽  
Jorge Guerra Mendes Junior ◽  
André Luis Mazzei Albert ◽  
Katia Christina Leandro
Keyword(s):  
Dietary Supplements ◽  
Screening Method ◽  
Rapid Screening ◽  
Rapid Screening Method

scholarly journals A Rapid Screening Method for Sibutramine Hydrochloride in Natural Herbal Medicines and Dietary Supplements

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Qi Liang ◽  
Yue Zhuang ◽  
Jun Ma ◽  
Jinyan Wang ◽  
Rui Feng ◽  
...  
Keyword(s):  
Dietary Supplements ◽  
Performance Metrics ◽  
Screening Method ◽  
Herbal Medicines ◽  
Rapid Test ◽  
Rapid Screening ◽  
Precipitation Reaction ◽  
Test Kit ◽  
Sibutramine Hydrochloride ◽  
Rapid Screening Method

Herbal weight loss drugs are becoming more widely used in the fight against obesity, but ineffective regulation of these products have resulted in harmful additives. These products may contain adulterants such as sibutramine hydrochloride that may result in serious adverse health events including death. This work established a color precipitation reaction-based rapid screening method for illegal adulteration of sibutramine hydrochloride in natural herbal medicines (NHM) and dietary supplements (DS). While a variety of chromatography- and electrophoresis-based systems have been reported to measure this analyte, they generally suffer from high costs, complicated sample preparation, and a costly analytical infrastructure. In contrast, we present a simple, handheld kit to assay for sibutramine. The performance metrics of this tool include an average detection time of approximately 3 minutes, which is markedly shorter than conventional methods (HPLC or HPLC-MS, etc.), a detection limit of 0.1 mg per aliquot, and an accuracy of 99.02% (n = 820). More strikingly, the sensitivity is 100% (n = 278), and the specificity is 98.52% (n = 542). The rapid test kit developed from this screening method was evaluated by FDA. In summary, this screening method is a rapid, simple, and low-cost tool for the detection of sibutramine in NHM and DS with superior selectivity and sensitivity. For these reasons, this method is especially suitable for underdeveloped settings because it can be employed onsite without any instrumentation. In addition, this approach could rapidly exclude most of the negative samples to boost efficiency in large-scale samples assay. If necessary, positive samples can undergo further alternate testing methods to confirm the positive results of sibutramine hydrochloride content.

Development of a simple and rapid screening method for the detection of 1-(3-chlorophenyl)piperazine in forensic samples

Talanta ◽  
2021 ◽  
pp. 122597
Author(s):  
Weberson P. Silva ◽  
Raquel G. Rocha ◽  
Luciano C. Arantes ◽  
Camila D. Lima ◽  
Larissa M.A. Melo ◽  
...  
Keyword(s):  
Screening Method ◽  
Rapid Screening ◽  
Forensic Samples ◽  
Rapid Screening Method

yAn on‐line target and rapid screening method for α ‐glucosidase inhibitors based on capillary electrophoresis

2021 ◽  
Author(s):  
Ying Zhang ◽  
Hai‐Yang Zhong ◽  
Stanislas Nsanzamahoro ◽  
Xiao‐Jun Yao ◽  
Wei‐Feng Wang ◽  
...  
Keyword(s):  
Capillary Electrophoresis ◽  
Screening Method ◽  
Rapid Screening ◽  
Glucosidase Inhibitors ◽  
Line Target ◽  
On Line ◽  
Rapid Screening Method

Rapid screening method to detect mutations inCYP21, the gene for 21-hydroxylase

2000 ◽  
Vol 94 (1) ◽  
pp. 28-31 ◽  
Author(s):  
Yuji Yokoyama ◽  
Michio Teraoka ◽  
Kazushiro Tsuji ◽  
Shinsuke Ninomiya ◽  
Chiyo Inoue ◽  
...  
Keyword(s):  
Screening Method ◽  
Rapid Screening ◽  
Rapid Screening Method

A highly sensitive, rapid screening method for the detection of antibodies directed against HLA class I and II antigens

1993 ◽  
Vol 6 (5) ◽  
pp. 277-280 ◽  
Author(s):  
A. W. Harmer ◽  
M. Sutton ◽  
A. Bayne ◽  
R. W. Vaughan ◽  
K. I. Welsh
Keyword(s):  
Screening Method ◽  
Hla Class I ◽  
Class I ◽  
Rapid Screening ◽  
Highly Sensitive ◽  
Rapid Screening Method
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