Brønsted acid-catalyzed metal- and solvent-free quinoline synthesis fromN-alkyl anilines and alkynes or alkenes

2018 ◽  
Vol 20 (1) ◽  
pp. 261-265 ◽  
Author(s):  
Waqar Ahmed ◽  
Sheng Zhang ◽  
Xiaoqiang Yu ◽  
Yoshinori Yamamoto ◽  
Ming Bao

A convenient and efficient method for quinoline synthesis was developed using simple and readily available starting materials under green conditions.

Synthesis ◽  
2018 ◽  
Vol 50 (12) ◽  
pp. 2416-2422 ◽  
Author(s):  
Man-Su Tu ◽  
Guang-Jian Mei ◽  
Feng Shi ◽  
Si-Jia Liu ◽  
Xiao-Li Jiang ◽  
...  

An efficient approach for the synthesis of chromene derivatives from vinyl o-quinone methides was established via a Brønsted acid catalyzed electrocyclization. By using this methodology, a series of structurally diversified chromenes was synthesized in a highly atom-economic and environmentally benign manner with generally good to excellent yields (up to 98% yield). This reaction will not only provide an efficient method for the construction of chromene scaffolds, but also enrich the research area of o-quinone methides.


2014 ◽  
Vol 55 (5) ◽  
pp. 1002-1005 ◽  
Author(s):  
Xiu-Jiang Du ◽  
Zhi-Peng Wang ◽  
Yan-Ling Hou ◽  
Cheng Zhang ◽  
Zheng-Ming Li ◽  
...  

Synthesis ◽  
2017 ◽  
Vol 49 (17) ◽  
pp. 4025-4034 ◽  
Author(s):  
Yang Shen ◽  
Zi-Qi Zhu ◽  
Jin-Xi Liu ◽  
Lei Yu ◽  
Bai-Xiang Du ◽  
...  

An efficient method for the synthesis of C3-alkylated indoles has been established via Brønsted acid catalyzed alkylation of 2-indolylmethanols with azlactones. The reaction exhibits broad substrate scope and delivers high yields (22 examples, up to 99% yield). This approach not only provides a new strategy for the direct synthesis of C3-alkylated indoles, but also represents a rarely reported alkylation between indole motifs and electron-rich synthons at the C3 position. This protocol serves as a good example of the application of the umpolung strategy in the synthesis of C3-alkylated indoles from 2-indolylmethanols.


2017 ◽  
Vol 54 (1) ◽  
pp. 54-63 ◽  
Author(s):  
Xu Li ◽  
Lan Wu ◽  
Qiong Tang ◽  
Jinxiang Dong

Author(s):  
Mizzanoor Rahaman ◽  
M. Shahnawaz Ali ◽  
Khorshada Jahan ◽  
Damon Hinz ◽  
Jawad Bin Belayet ◽  
...  

2021 ◽  
pp. 152751
Author(s):  
Wenming Chen ◽  
Guifang Chen ◽  
Biao Wang ◽  
Wei Wang ◽  
Wei Huang ◽  
...  

2021 ◽  
Author(s):  
Alesandere Ortega ◽  
Uxue Uria ◽  
Tomás Tejero ◽  
Liher Prieto ◽  
Efraim Reyes ◽  
...  

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