An environmentally benign and efficient synthesis of substituted benzothiazole-2-thiols, benzoxazole-2-thiols, and benzimidazoline-2-thiones in water

2017 ◽  
Vol 19 (23) ◽  
pp. 5591-5598 ◽  
Author(s):  
Xing Liu ◽  
Min Liu ◽  
Wan Xu ◽  
Meng-Tian Zeng ◽  
Hui Zhu ◽  
...  
Keyword(s):  
Practical Method ◽  
Environmentally Benign ◽  
Efficient Synthesis ◽  
One Step ◽  
The One

An efficient and practical method for the one-step synthesis of benzothiazole-2-thiols, benzoxazole-2-thiols and benzimidazoline-2-thiones in water was described.

Protecting group free synthesis of urea-linked glycoconjugates: efficient synthesis of β-urea glycosides in aqueous solution

2014 ◽  
Vol 12 (23) ◽  
pp. 3924-3931 ◽  
Author(s):  
Yoshiyasu Ichikawa ◽  
Takahiro Minami ◽  
Shohei Kusaba ◽  
Nobuyoshi Saeki ◽  
Yuta Tonegawa ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Protecting Group ◽  
Efficient Synthesis ◽  
Acidic Aqueous Solution ◽  
Step Process ◽  
One Step ◽  
The One

The one step process, involving reactions between urea and protecting group free d-glucose, N-acetyl-d-glucosamine or d-xylose in acidic aqueous solution, furnishes the corresponding β-urea glycosides.

Sulfuryl Fluoride Promoted Thiocyanation of Alcohols: A Practical Method for Preparing Thiocyanates

Synlett ◽  
2020 ◽  
Vol 31 (14) ◽  
pp. 1413-1417
Author(s):  
Chengrong Ding ◽  
Guofu Zhang ◽  
Lidi Xuan ◽  
Yiyong Zhao
Keyword(s):  
Ethyl Acetate ◽  
Functional Group ◽  
High Efficiency ◽  
Bond Cleavage ◽  
Ammonium Thiocyanate ◽  
Practical Method ◽  
Sulfuryl Fluoride ◽  
Mild Conditions ◽  
One Step ◽  
The One

A novel SO2F2-promoted thiocyanation method for the one-step synthesis of thiocyanates through C–O bond cleavage of readily available alcohols with ammonium thiocyanate as the thiocyanating agent was developed. The method avoids the use of additional catalyst, and a variety of (hetero)arene, alkene and aliphatic alcohols reacted with high efficiency in ethyl acetate under mild conditions to afford the corresponding thiocyanates in excellent to quantitative yields with broad functional-group compatibility.

Direct and facile synthesis of acyl azides from carboxylic acids using the trichloroisocyanuric acid–triphenylphosphine system

2013 ◽  
Vol 91 (3) ◽  
pp. 181-185 ◽  
Author(s):  
Batool Akhlaghinia ◽  
Hamed Rouhi-Saadabad
Keyword(s):  
Carboxylic Acids ◽  
Practical Method ◽  
Facile Synthesis ◽  
One Step ◽  
Acyl Azides ◽  
The One ◽  
Trichloroisocyanuric Acid

A mild, efficient, and practical method for the one-step synthesis of acyl azides from carboxylic acids using a safe and inexpensive mixed reagent, trichloroisocyanuric acid–triphenylphosphine, is described.

One-Step CVD Synthesis of Few-Layer SnS2/MoS2 Vertical Heterostructures

NANO ◽  
2019 ◽  
Vol 14 (10) ◽  
pp. 1950129 ◽  
Author(s):  
Hongxiao Zhao ◽  
Yong Yan ◽  
Xiaohui Song ◽  
Aodi Dong ◽  
Jian Su ◽  
...  
Keyword(s):  
Vapor Deposition ◽  
2D Materials ◽  
Chemical Vapor ◽  
Practical Method ◽  
Cvd Method ◽  
Cvd Synthesis ◽  
One Step ◽  
The One ◽  
Controllable Fabrication ◽  
First Time

Constructing van der Waals (vdW) heterostructures with various-layered two-dimensional (2D) materials is attractive to design various materials and devices. For controllable fabrication of vdW heterostructures, it is very important to make the growth process clear. In this work, SnS2/MoS2 vertical heterostructures were synthesized by the one-step chemical vapor deposition (CVD) method. The bottom MoS2 triangle layers can be partially or completely covered by SnS2 layers. The interlayer charge separation was also observed in the heterostructures by photoluminescence (PL) spectroscopy. The growth mechanism of SnS2/MoS2 vertical heterostructures was also discussed for the first time. MoS2 triangle layers form on the substrates at first and then grow a top layer of SnS2. This study will provide an important and practical method, as a guidance to prepare high-quality vertical heterostructures.

A Study on the Rearrangement of Dialkyl 1-Aryl-1-hydroxymethylphosphonates to Benzyl Phosphates

2020 ◽  
Vol 24 (4) ◽  
pp. 465-471 ◽  
Author(s):  
Zita Rádai ◽  
Réka Szabó ◽  
Áron Szigetvári ◽  
Nóra Zsuzsa Kiss ◽  
Zoltán Mucsi ◽  
...  
Keyword(s):  
Quantum Chemical ◽  
Room Temperature ◽  
Phase Transfer ◽  
One Pot ◽  
Substrate Dependence ◽  
Triethylbenzylammonium Chloride ◽  
One Step ◽  
The Pudovik Reaction ◽  
The One ◽  
Solid Liquid

The phospha-Brook rearrangement of dialkyl 1-aryl-1-hydroxymethylphosphonates (HPs) to the corresponding benzyl phosphates (BPs) has been elaborated under solid-liquid phase transfer catalytic conditions. The best procedure involved the use of triethylbenzylammonium chloride as the catalyst and Cs2CO3 as the base in acetonitrile as the solvent at room temperature. The substrate dependence of the rearrangement has been studied, and the mechanism of the transformation under discussion was explored by quantum chemical calculations. The key intermediate is an oxaphosphirane. The one-pot version starting with the Pudovik reaction has also been developed. The conditions of this tandem transformation were the same, as those for the one-step HP→BP conversion.

A Simple Synthesis of the Anticancer Drug Altretamine

2020 ◽  
Vol 17 (8) ◽  
pp. 628-630
Author(s):  
Vu Binh Duong ◽  
Pham Van Hien ◽  
Tran Thai Ngoc ◽  
Phan Dinh Chau ◽  
Tran Khac Vu
Keyword(s):  
Aqueous Solution ◽  
Anticancer Drug ◽  
Potassium Hydroxide ◽  
Large Scale ◽  
Synthesis Method ◽  
Practical Method ◽  
Cyanuric Chloride ◽  
Simple Synthesis ◽  
High Yield ◽  
One Step

A simple and practical method for the synthesis on a large scale of altretamine (1), a wellknown antitumor drug, has been successfully developed. The synthesis method involves the conversion of cyanuric chloride (2) into altretamine (1) by dimethylamination of 2 with an aqueous solution of 40% dimethylamine and potassium hydroxide in 1, -dioxan 4in one step to give altretamine (1) in high yield.

Metal and Non-Metal Catalysts in the Synthesis of Five-Membered S-Heterocycles

2019 ◽  
Vol 16 (2) ◽  
pp. 258-275 ◽  
Author(s):  
Navjeet Kaur
Keyword(s):  
Organic Synthesis ◽  
Biological Activities ◽  
Reaction Times ◽  
Research Field ◽  
Environmentally Benign ◽  
Metal Catalyst ◽  
Efficient Synthesis ◽  
Heterocyclic Molecules ◽  
The Past ◽  
Harsh Conditions

Background:A wide variety of biological activities are exhibited by N, O and S containing heterocycles and recently, many reports appeared for the synthesis of these heterocycles. The synthesis of heterocycles with the help of metal and non-metal catalyst has become a highly rewarding and important method in organic synthesis. This review article concentrated on the synthesis of S-heterocylces in the presence of metal and non-metal catalyst. The synthesis of five-membered S-heterocycles is described here.Objective:There is a need for the development of rapid, efficient and versatile strategy for the synthesis of heterocyclic rings. Metal, non-metal and organocatalysis involving methods have gained prominence because traditional conditions have disadvantages such as long reaction times, harsh conditions and limited substrate scope.Conclusion:The metal-, non-metal-, and organocatalyst assisted organic synthesis is a highly dynamic research field. For ßthe chemoselective and efficient synthesis of heterocyclic molecules, this protocol has emerged as a powerful route. Various methodologies in the past few years have been pointed out to pursue more sustainable, efficient and environmentally benign procedures and products. Among these processes, the development of new protocols (catalysis), which avoided the use of toxic reagents, are the focus of intense research.

scholarly journals One-Year Clinical Evaluation of the Bonding Effectiveness of a One-Step, Self-Etch Adhesive in Noncarious Cervical Lesion Therapy

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Babacar Faye ◽  
Mouhamed Sarr ◽  
Khaly Bane ◽  
Adjaratou Wakha Aidara ◽  
Seydina Ousmane Niang ◽  
...  
Keyword(s):  
Clinical Performance ◽  
Retention Rate ◽  
Recall Rate ◽  
Acid Etching ◽  
Significant Difference ◽  
Usphs Criteria ◽  
One Step ◽  
One Year ◽  
The One ◽  
Self Etch

This study evaluated the one-year clinical performance of a one-step, self-etch adhesive (Optibond All-in-One, Kerr, CA, USA) combined with a composite (Herculite XRV Ultra, Kerr Hawe, CA, USA) to restore NCCLs with or without prior acid etching. Restorations performed by the same practitioner were evaluated at baseline and after 3, 6, and 12 months using modified USPHS criteria. At 6 months, the recall rate was 100%. The retention rate was 84.2% for restorations with prior acid etching, but statistically significant differences were observed between baseline and 6 months. Without acid etching, the retention rate was 77%, and no statistically significant difference was noted between 3 and 6 months. Marginal integrity (93.7% with and 87.7% without acid etching) and discoloration (95.3% with and 92.9% without acid etching) were scored as Alpha or Bravo, with better results after acid etching. After one year, the recall rate was 58.06%. Loss of pulp vitality, postoperative sensitivity, or secondary caries were not observed. After one year retention rate was of 90.6% and 76.9% with and without acid conditioning. Optibond All-in-One performs at a satisfactory clinical performance level for restoration of NCCLs after 12 months especially after acid etching.

scholarly journals Building up cyclodextrins from scratch – templated enzymatic synthesis of cyclodextrins directly from maltose

2021 ◽  
Author(s):  
Dennis Larsen ◽  
Sophie R. Beeren
Keyword(s):  
Enzymatic Synthesis ◽  
Combinatorial Libraries ◽  
One Step ◽  
The One ◽  
Kinetic Trapping

Template-induced kinetic trapping of specific cyclodextrins in enzyme-mediated dynamic combinatorial libraries of linear and cyclic α-glucans enables the one-step synthesis of cyclodextrins from maltose in water.

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