The development of aPanax notoginsengmedicinal liquor processing technology using the response surface method and a study of its antioxidant activity and its effects on mouse melanoma B16 cells

2017 ◽  
Vol 8 (11) ◽  
pp. 4251-4264 ◽  
Author(s):  
Liao Peiran ◽  
Liu Ying ◽  
Zhao Mingzhuo ◽  
Yang Ye ◽  
Cui Xiuming

The optimum process forPanax notoginsengmedicinal liquor was as following: ratio of solution to solid 32 : 1, alcohol content 53% and soaking time 35 d.Panax notoginsengmedicinal liquor could play the role of functional food in anti-oxidation and anti-melanin deposition.

Materials ◽  
2020 ◽  
Vol 13 (21) ◽  
pp. 4879
Author(s):  
Mireia Vilanova ◽  
Rubén Escribano-García ◽  
Teresa Guraya ◽  
Maria San Sebastian

A method to find the optimum process parameters for manufacturing nickel-based superalloy Inconel 738LC by laser powder bed fusion (LPBF) technology is presented. This material is known to form cracks during its processing by LPBF technology; thus, process parameters have to be optimized to get a high quality product. In this work, the objective of the optimization was to obtain samples with fewer pores and cracks. A design of experiments (DoE) technique was implemented to define the reduced set of samples. Each sample was manufactured by LPBF with a specific combination of laser power, laser scan speed, hatch distance and scan strategy parameters. Using the porosity and crack density results obtained from the DoE samples, quadratic models were fitted, which allowed identifying the optimal working point by applying the response surface method (RSM). Finally, five samples with the predicted optimal processing parameters were fabricated. The examination of these samples showed that it was possible to manufacture IN738LC samples free of cracks and with a porosity percentage below 0.1%. Therefore, it was demonstrated that RSM is suitable for obtaining optimum process parameters for IN738LC alloy manufacturing by LPBF technology.


2019 ◽  
Vol 130 ◽  
pp. 467-477 ◽  
Author(s):  
Govindasamy Sharmila ◽  
Chandrasekaran Muthukumaran ◽  
Elangovan Suriya ◽  
Rajasekar Muppidathi Keerthana ◽  
Mani Kamatchi ◽  
...  

2013 ◽  
Vol 781-784 ◽  
pp. 1856-1860 ◽  
Author(s):  
Li Na Zhao ◽  
Shao Yun Wang ◽  
Shun Li Huang ◽  
Yi Fan Huang

To optimum the chelation technology of whey protein hydrolysate with calcium, the response surface method was used to investigate optimized technological conditions. The result showed that the optimum process parameters for the whey protein hydrolysate-calcium chelation were whey protein peptide and CaCl2 ratio of 24 : 1 (w/w), whey protein hydrolysate concentration 3.5 %, pH 7.5, reaction time 20 min, reaction temperature 30 °C. Finally, the optimum level was established and whey protein hydrolysate-calcium chelate was obtained, which can provide basic theories for the following function and activity evaluation of this potential calcium supplement.


2019 ◽  
Vol 78 ◽  
pp. 02015
Author(s):  
Xiaojuan Liu ◽  
Zhong Li

In this paper, the effects of extraction temperature, extraction pressure and dosage of entrainer on flavonoids yield were studied. The optimal process determined by response surface method was extraction temperature as 48.52°, extraction pressure as 40MPa, dosage of entrainer as 36.13mL, theoretical predictive yield as 0.791%, actual verified yield as 0.793%, and there was an interaction between the extraction temperature and dosage of entrainer. The optimum process determined by orthogonal design was extraction temperature as 50°, extraction pressure as 40MPa, dosage of entrainer as 37.5mL, and actual verified yield as 0.779%. Although the two methods obtained similar best processes, the response surface method could provide more accurate information, and the final flavonoids yield was also highest, which was worth promoting.


2017 ◽  
Vol 264 ◽  
pp. 182-185
Author(s):  
Mohammad Anas Zainal Abidin ◽  
Mohd Fairuz Dimin ◽  
Md Radzai Said ◽  
Sian Meng Se ◽  
Azizah Shaaban ◽  
...  

Fluidised bed technology is commonly applied in the pharmaceutical, agricultural and food production technology. The aim of this work is to identify the optimum process parameters in order to gain the best hardness and density values for the urea granules from the fluidised bed granulation. The layout of the experiments are based on Central Composite Design of Response Surface Method. The analyzed data shown that the optimize value for each of these parameter are 0.10MPa, 32.11Hz, 50% w/w, 42.250C for spray pressure, fan speed, urea solution concentration and inlet air temperature with 1.71 kgf/granule hardness and 1.85 g/cm3 density were predicted. Experimentally, using the predicted optimize input parameter, the hardness and density observed were 0.20 kgf/granule and 1.30 g/cm3 respectively.


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