Exploring the effect of substituent in the hydrazone ligand of a family of μ-oxidodivanadium(v) hydrazone complexes on structure, DNA binding and anticancer activity

2017 ◽  
Vol 46 (46) ◽  
pp. 16276-16293 ◽  
Author(s):  
Debashis Patra ◽  
Subhabrata Paul ◽  
Indira Majumder ◽  
Nayim Sepay ◽  
Sachinath Bera ◽  
...  
Keyword(s):  
Dna Binding ◽  
Anticancer Activity ◽  
Hydrazone Ligand ◽  
Hydrazone Complexes

The effect of substituent in the hydrazone ligand of each of two μ-oxidodivanadium(v) hydrazones on structure and anticancer activity has been explored.

scholarly journals Anticancer activity of pyrimidodiazepines based on 2-chloro-4-anilinoquinazoline: synthesis, DNA binding and molecular docking

RSC Advances ◽  
2021 ◽  
Vol 11 (38) ◽  
pp. 23310-23329
Author(s):  
Viviana Cuartas ◽  
Alberto Aragón-Muriel ◽  
Yamil Liscano ◽  
Dorian Polo-Cerón ◽  
Maria del Pilar Crespo-Ortiz ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Dna Binding ◽  
Tumor Cell ◽  
Anticancer Activity ◽  
Cell Lines ◽  
Human Tumor ◽  
Tumor Cell Lines ◽  
Human Tumor Cell ◽  
Human Tumor Cell Lines

A new series of quinazoline-based chalcones and pyrimidodiazepines were tested against 60 human tumor cell lines.

Anticancer Activity, DNA Binding, and Photodynamic Properties of a N∧C∧N-Coordinated Pt(II) Complex

2021 ◽  
Author(s):  
Stefano Scoditti ◽  
Eslam Dabbish ◽  
Nino Russo ◽  
Gloria Mazzone ◽  
Emilia Sicilia
Keyword(s):  
Dna Binding ◽  
Anticancer Activity

Cadmium(II) complexes of a hydrazone ligand: Synthesis, characterization, DNA binding, cyto- and genotoxicity studies

Polyhedron ◽  
2019 ◽  
Vol 171 ◽  
pp. 237-248 ◽  
Author(s):  
Ali Akbar Khandar ◽  
Zahra Mahmoudi Azar ◽  
Morteza Eskandani ◽  
Christian B. Hubschle ◽  
Sander van Smaalen ◽  
...  
Keyword(s):  
Dna Binding ◽  
Hydrazone Ligand ◽  
Ligand Synthesis

scholarly journals Copper(ii) complexes based on quinoline-derived Schiff-base ligands: synthesis, characterization, HSA/DNA binding ability, and anticancer activity

MedChemComm ◽  
2018 ◽  
Vol 9 (10) ◽  
pp. 1663-1672 ◽  
Author(s):  
Kun Hu ◽  
Chensi Liu ◽  
Jingui Li ◽  
Fupei Liang
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Tumor Cell ◽  
Anticancer Activity ◽  
Hela Cells ◽  
Cell Apoptosis ◽  
Schiff Base Ligands ◽  
Binding Ability ◽  
Tumor Cell Apoptosis ◽  
Cell Cycles

Three Cu(ii) complexes (C1–C3) were designed and synthesized.C3, in particular, having a ligand derived from benzocaine, exhibited greater selectivity toward HeLa cells, arrested cell cycles, and promoted tumor cell apoptosis.

Anticancer activity and DNA binding property of the dimers of triphenylethylene–coumarin hybrid with two amino side chains

2014 ◽  
Vol 24 (6) ◽  
pp. 2314-2324 ◽  
Author(s):  
Mo Zhu ◽  
Likai Zhou ◽  
Yuchao Yao ◽  
Shuai Li ◽  
Mengjiao Lv ◽  
...  
Keyword(s):  
Dna Binding ◽  
Anticancer Activity ◽  
Binding Property ◽  
Side Chains ◽  
Dna Binding Property

Synthesis, spectroscopic investigation, and DFT study of N,N′-disubstituted ferrocene-based thiourea complexes as potent anticancer agents

2018 ◽  
Vol 47 (6) ◽  
pp. 1868-1878 ◽  
Author(s):  
Faiza Asghar ◽  
Saira Fatima ◽  
Sadaf Rana ◽  
Amin Badshah ◽  
Ian S. Butler ◽  
...  
Keyword(s):  
Dna Binding ◽  
Anticancer Activity ◽  
Binding Affinity ◽  
Anticancer Agents ◽  
Spectroscopic Investigation ◽  
Dft Study ◽  
Redox Potentials ◽  
Dna Binding Affinity ◽  
Dna Binders ◽  
Homo Lumo

The DNA binding affinity of ferrocenyl thioureas (A1–A9) explored by CV and UV ascertain them as noble DNA binders. The complexes also publicized decent antioxidant and anticancer activity. DFT-based HOMO/LUMO energies are comparable with experimentally calculated redox potentials.

Synthesis, DNA binding affinity and anticancer activity of novel 4H-benzo[g][1,2,3]triazolo[5,1-c][1,4]oxazocines

2016 ◽  
Vol 14 (39) ◽  
pp. 9294-9305 ◽  
Author(s):  
K. N. Visweswara Sastry ◽  
Sunitha Rani Routhu ◽  
Soma Gupta Datta ◽  
Narayana Nagesh ◽  
Bathini Nagendra Babu ◽  
...  
Keyword(s):  
Dna Binding ◽  
Anticancer Activity ◽  
Binding Affinity ◽  
Cancer Therapeutics ◽  
New Class ◽  
Dna Binding Affinity

Cancer therapeutics: a new class of anticancer heterocycles was synthesized.

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