Understanding receptor-mediated endocytosis of elastic nanoparticles through coarse grained molecular dynamic simulation

2018 ◽  
Vol 20 (24) ◽  
pp. 16372-16385 ◽  
Author(s):  
Zhiqiang Shen ◽  
Huilin Ye ◽  
Ying Li
Keyword(s):  
Molecular Dynamic Simulation ◽  
Molecular Dynamic ◽  
Dynamic Simulation ◽  
Contact Area ◽  
Late Stage ◽  
Early Stage ◽  
Coarse Grained ◽  
Large Energy ◽  
Receptor Mediated Endocytosis ◽  
Large Contact Area

The membrane wrapping of the soft nanoparticle (NP) is faster than that of the stiff one at the early stage, due to the NP deformation induced large contact area between the NP and membrane. However, because of the large energy penalties induced by the NP deformation, the membrane wrapping speed of soft NPs slows down during the late stage.

Vesicle formation of catanionic mixtures of CTAC/SDS induced by ratio: a coarse-grained molecular dynamic simulation study

RSC Advances ◽  
2016 ◽  
Vol 6 (16) ◽  
pp. 13442-13449 ◽  
Author(s):  
Pan Wang ◽  
Yunyun Ma ◽  
Zhibin Liu ◽  
Youguo Yan ◽  
Xiaoli Sun ◽  
...  
Keyword(s):  
Molecular Dynamic Simulation ◽  
Molecular Dynamic ◽  
Dynamic Simulation ◽  
Simulation Study ◽  
Coarse Grained ◽  
Vesicle Formation ◽  
Molecular Dynamic Simulation Study ◽  
Catanionic Mixtures

A vesicle was formed by disk-like bilayer curling.

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