Ligand-induced action of the W2866.48 rotamer toggle switch in the β2-adrenergic receptor

2018 ◽  
Vol 20 (1) ◽  
pp. 581-594 ◽  
Author(s):  
Anita Plazinska ◽  
Wojciech Plazinski ◽  
Rafal Luchowski ◽  
Artur Wnorowski ◽  
Wojciech Grudzinski ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Fluorescence Spectroscopy ◽  
Adrenergic Receptor ◽  
Toggle Switch ◽  
Spectroscopy Study ◽  
Time Resolved Fluorescence ◽  
Time Resolved ◽  
Β2 Adrenergic Receptor

The combined molecular dynamics and time-resolved fluorescence spectroscopy study reveals how the pharmacological character of the bound ligand is connected with its influence on the toggle switch of the β2-adrenergic receptor.

Cell-based β2-adrenergic receptor–ligand binding assay using synthesized europium-labeled ligands and time-resolved fluorescence

2009 ◽  
Vol 392 (2) ◽  
pp. 103-109 ◽  
Author(s):  
Eija Martikkala ◽  
Mirva Lehmusto ◽  
Minna Lilja ◽  
Anita Rozwandowicz-Jansen ◽  
Jenni Lunden ◽  
...  
Keyword(s):  
Ligand Binding ◽  
Adrenergic Receptor ◽  
Binding Assay ◽  
Ligand Binding Assay ◽  
Time Resolved Fluorescence ◽  
Receptor Ligand ◽  
Time Resolved ◽  
Β2 Adrenergic Receptor

Molecular Dynamics of the Anti-Fluorescein 4-4-20 Antigen-Binding Fragment. 2. Time-Resolved Fluorescence Spectroscopy

Biochemistry ◽  
1995 ◽  
Vol 34 (21) ◽  
pp. 6975-6984 ◽  
Author(s):  
Kap Lim ◽  
David M. Jameson ◽  
Christine A. Gentry ◽  
James N. Herron
Keyword(s):  
Molecular Dynamics ◽  
Fluorescence Spectroscopy ◽  
Antigen Binding ◽  
Time Resolved Fluorescence ◽  
Time Resolved

Time-resolved fluorescence spectroscopy study of excited state dynamics of alkyl- and benzo-substituted triphyrin(2.1.1)

2014 ◽  
Vol 16 (26) ◽  
pp. 13129-13135 ◽  
Author(s):  
Yusuke Iima ◽  
Daiki Kuzuhara ◽  
Zhao-Li Xue ◽  
Seiji Akimoto ◽  
Hiroko Yamada ◽  
...  
Keyword(s):  
Excited State ◽  
Fluorescence Spectroscopy ◽  
Spectroscopy Study ◽  
Time Resolved Fluorescence ◽  
Radiative Relaxation ◽  
Time Resolved ◽  
Excited State Dynamics

Non-radiative relaxation in triphyrin(2.1.1) is found to be due to non-planarity of the macrocycle.

Sign in / Sign up

Export Citation Format

Share Document